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The map label for this gene is hybB [C]

Identifier: 51893737

GI number: 51893737

Start: 2788295

End: 2789365

Strand: Reverse

Name: hybB [C]

Synonym: STH2599

Alternate gene names: 51893737

Gene position: 2789365-2788295 (Counterclockwise)

Preceding gene: 51893738

Following gene: 51893736

Centisome position: 78.22

GC content: 66.39

Gene sequence:

>1071_bases
ATGGGCCTGGGCGCCGCCACGGGGCTCAACGACTCGATGCCCTGGGGCCTGTGGAAGATCTACGACGTCGTGGTGGTGGT
GCCGCTGGGCGCCACGGGGTTCGTGATGGCCTTCATCCGCTACTTCACGCCGGGCGGCGAGCGGTACGAGTACCTGAACC
GCCGGGCGGTGATCTGGGCGGCCATCATGTACCTCTCCATGGGCGTCCGGCTGGCGTTCGACATCGGGATCCCCTGGCGC
ATCATCTACCCGATCGTGCGGGGCGGCAACCTGCACTCGCCGCTGTTTGAGATCGCCTGGTGCGTGTTCCTCTACCTGAT
CGTGCTCTTCTTCGAGAACATCAGCCGGGTGGCGGAGGAGCAGAAGCGGCCCTGGGTCAAGAAGGCCGACCACCTGCTCC
ACAAGATCCTGCCGGGGTTCGTGCTGGTGGGCGTGATGCTTTCGACGATGCACCACTCGTCCCTGGGCACCCTGTTCATG
ATCACCGGCAAGCGGATGGATCCGCTCTGGTACCACCCCTGGCTGAACTACGTCTTCCTGCTGACCTCCATCGCCACCGG
CATGGGCATGATGATGGTCATCGAACACCTGACCAGCCGGTACTACAAGATCAAGTTCGAGACCGACCTGCTGGCTCGCC
TGGCGCCGTGGGTCGCCGGCATCCTCAGCTTCGTGCTGGCCTGGCGTCTCGGCGCCATGGCCGCCGAGGGGCAGATCGGG
CAGATCTTCGTGCCCCGGGTAGAGACCGCGCTCTGGTGGGCGGAGATCCTGCTGGGCTACGTGGCCCCGATCGCCATCCT
CTTCTCCCGGGCCCGGTTCACCCAGAAGGGGCTGTTCGCCGGCGGCCTGCTCACCGTGCTGGGTATGATCGCCCTGCGGC
TGAACGTGGGCTTCACGGCCCTGATGGATGCGCTGGGCGCCCAGTACACGCCGTCGGTCCCGGAGATCCTGTTCAGCGTC
GGCGCCACCGCCGGCACCGTGGTCATCTACACCTGGTTCGTGGAAACCTTGCCCTCCATCCTCGGCCCGCGGGAGCGGGA
GACCGAGGGGCTGGAGGCAGTGGGGGACTAG

Upstream 100 bases:

>100_bases
TCTGCGGATGGAGTGGTGGCGCTGGCGGATGTCGCCGGGCAAGGGGCTGTTGCTCGCCCTCTTCGGTGCGGCGGCGGTGG
TGGCGGTCTGGCGCCTCTTC

Downstream 100 bases:

>100_bases
CTGCTGCGGCAGCGGAGGAGGGAACTTCCGTGACGACGTGGGCCTATGCCGAGCAGATCCTTTACGTGGACCTCGGGCGC
CGCACCGCGCGCGTCGAGCC

Product: putative cytochrome Ni/Fe component of hydrogenase

Products: NA

Alternate protein names: HMC operon ORF 3 [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MGLGAATGLNDSMPWGLWKIYDVVVVVPLGATGFVMAFIRYFTPGGERYEYLNRRAVIWAAIMYLSMGVRLAFDIGIPWR
IIYPIVRGGNLHSPLFEIAWCVFLYLIVLFFENISRVAEEQKRPWVKKADHLLHKILPGFVLVGVMLSTMHHSSLGTLFM
ITGKRMDPLWYHPWLNYVFLLTSIATGMGMMMVIEHLTSRYYKIKFETDLLARLAPWVAGILSFVLAWRLGAMAAEGQIG
QIFVPRVETALWWAEILLGYVAPIAILFSRARFTQKGLFAGGLLTVLGMIALRLNVGFTALMDALGAQYTPSVPEILFSV
GATAGTVVIYTWFVETLPSILGPRERETEGLEAVGD

Sequences:

>Translated_356_residues
MGLGAATGLNDSMPWGLWKIYDVVVVVPLGATGFVMAFIRYFTPGGERYEYLNRRAVIWAAIMYLSMGVRLAFDIGIPWR
IIYPIVRGGNLHSPLFEIAWCVFLYLIVLFFENISRVAEEQKRPWVKKADHLLHKILPGFVLVGVMLSTMHHSSLGTLFM
ITGKRMDPLWYHPWLNYVFLLTSIATGMGMMMVIEHLTSRYYKIKFETDLLARLAPWVAGILSFVLAWRLGAMAAEGQIG
QIFVPRVETALWWAEILLGYVAPIAILFSRARFTQKGLFAGGLLTVLGMIALRLNVGFTALMDALGAQYTPSVPEILFSV
GATAGTVVIYTWFVETLPSILGPRERETEGLEAVGD
>Mature_355_residues
GLGAATGLNDSMPWGLWKIYDVVVVVPLGATGFVMAFIRYFTPGGERYEYLNRRAVIWAAIMYLSMGVRLAFDIGIPWRI
IYPIVRGGNLHSPLFEIAWCVFLYLIVLFFENISRVAEEQKRPWVKKADHLLHKILPGFVLVGVMLSTMHHSSLGTLFMI
TGKRMDPLWYHPWLNYVFLLTSIATGMGMMMVIEHLTSRYYKIKFETDLLARLAPWVAGILSFVLAWRLGAMAAEGQIGQ
IFVPRVETALWWAEILLGYVAPIAILFSRARFTQKGLFAGGLLTVLGMIALRLNVGFTALMDALGAQYTPSVPEILFSVG
ATAGTVVIYTWFVETLPSILGPRERETEGLEAVGD

Specific function: HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates [H]

COG id: COG5557

COG function: function code C; Polysulphide reductase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

Organism=Escherichia coli, GI2367183, Length=353, Percent_Identity=26.3456090651558, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 39832; Mature: 39701

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLGAATGLNDSMPWGLWKIYDVVVVVPLGATGFVMAFIRYFTPGGERYEYLNRRAVIWA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AIMYLSMGVRLAFDIGIPWRIIYPIVRGGNLHSPLFEIAWCVFLYLIVLFFENISRVAEE
HHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKRPWVKKADHLLHKILPGFVLVGVMLSTMHHSSLGTLFMITGKRMDPLWYHPWLNYVFL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHH
LTSIATGMGMMMVIEHLTSRYYKIKFETDLLARLAPWVAGILSFVLAWRLGAMAAEGQIG
HHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QIFVPRVETALWWAEILLGYVAPIAILFSRARFTQKGLFAGGLLTVLGMIALRLNVGFTA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LMDALGAQYTPSVPEILFSVGATAGTVVIYTWFVETLPSILGPRERETEGLEAVGD
HHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure 
GLGAATGLNDSMPWGLWKIYDVVVVVPLGATGFVMAFIRYFTPGGERYEYLNRRAVIWA
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AIMYLSMGVRLAFDIGIPWRIIYPIVRGGNLHSPLFEIAWCVFLYLIVLFFENISRVAEE
HHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKRPWVKKADHLLHKILPGFVLVGVMLSTMHHSSLGTLFMITGKRMDPLWYHPWLNYVFL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHH
LTSIATGMGMMMVIEHLTSRYYKIKFETDLLARLAPWVAGILSFVLAWRLGAMAAEGQIG
HHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QIFVPRVETALWWAEILLGYVAPIAILFSRARFTQKGLFAGGLLTVLGMIALRLNVGFTA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LMDALGAQYTPSVPEILFSVGATAGTVVIYTWFVETLPSILGPRERETEGLEAVGD
HHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8335628 [H]