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The map label for this gene is uppP

Identifier: 51893633

GI number: 51893633

Start: 2677381

End: 2678211

Strand: Reverse

Name: uppP

Synonym: STH2495

Alternate gene names: 51893633

Gene position: 2678211-2677381 (Counterclockwise)

Preceding gene: 51893634

Following gene: 51893632

Centisome position: 75.1

GC content: 69.43

Gene sequence:

>831_bases
TTGCTGTTTATTGGCAAGACAACGGAGGGATTCCCCGTGACCGTCCTTCAGGCCGTCATCCTCGGCATCGTGCAGGGGCT
GGCCGAGTTCCTGCCCATCTCCAGCTCCGCCCACCTGATCCTGGTCCCGTGGTTCCTGGGCTGGTCGCCCTCGGGCCTGG
CTTTCGATCTGGCCCTGCACGTGGGCACCCTCATCGCCGTCACCATCTACTTCTGGCGGGACCTGCTGAATCTGGCGGTG
GAGGGGCTGACGAAGGGGATGAAGACCCCCACCGGCAGGCTGGCCTGGGGGATCGTGCTGGGGACGGTGCCCGGGGCGAT
CTTCGGCCTCCTGATGGAGGACGTGGTGGAGGCGGTCTTCCGCCAGTCCATCCTCACCATCGCCCTCCTGCTGGCGGTGG
TGGGCGTCATCCTGTACCTGGCCGACCGGTTCGGCCCCAAGCGGCGGTCGCTGGAGGAGATCCGGGTGTCGGACGTGATC
TGGATCGGGCTGGCGCAGGCGCTGGCCGTGATCCCCGGCGTCTCCCGGTCGGGCGCGACCATCACCGCCGGCCTGGCCCT
GGGGCTGAAGCGGGAGACCGCGGCGAAGGTCTCGTTCCTGCTGGGCTGGCCGATCATCCTGGGCGGGGCGGTGCTGGTAA
TCCCCGACGCGGATCCCGCCATGTTCACGCCGTCTTTCTTCGCCGGCGTGGCGGCCGCGGCGGTGAGCGGATACGCGGTC
ATCGCCGCGCTGCTCCGGTACCTGCAGCGGGGGTCCTACCTGGTCTTTGCCTGGTACCGGGGGCTCGTGGCCGCGGTCAC
CGTGGCGCTGCTGCTGGCGCGGGGGATGTGA

Upstream 100 bases:

>100_bases
TGGGTGCCCGCTTCCGCGGACTAGCGGCTCCTCCGGGCCGACCGGAGGGCCGACGGAGGGCAGACAGAGGTGGCCCTGCG
CCCGCCCGTATGGTACACTG

Downstream 100 bases:

>100_bases
TCTGCGCAGACCAGGACGCGGCTTTTCTGTGTCCTGGTCCCTTTTCTTTCTGAGGCCGCTGCGGCGGTGCTGTCCACGGG
GGCGGCCAGGACGTGTCGAC

Product: putative undecaprenol kinase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MLFIGKTTEGFPVTVLQAVILGIVQGLAEFLPISSSAHLILVPWFLGWSPSGLAFDLALHVGTLIAVTIYFWRDLLNLAV
EGLTKGMKTPTGRLAWGIVLGTVPGAIFGLLMEDVVEAVFRQSILTIALLLAVVGVILYLADRFGPKRRSLEEIRVSDVI
WIGLAQALAVIPGVSRSGATITAGLALGLKRETAAKVSFLLGWPIILGGAVLVIPDADPAMFTPSFFAGVAAAAVSGYAV
IAALLRYLQRGSYLVFAWYRGLVAAVTVALLLARGM

Sequences:

>Translated_276_residues
MLFIGKTTEGFPVTVLQAVILGIVQGLAEFLPISSSAHLILVPWFLGWSPSGLAFDLALHVGTLIAVTIYFWRDLLNLAV
EGLTKGMKTPTGRLAWGIVLGTVPGAIFGLLMEDVVEAVFRQSILTIALLLAVVGVILYLADRFGPKRRSLEEIRVSDVI
WIGLAQALAVIPGVSRSGATITAGLALGLKRETAAKVSFLLGWPIILGGAVLVIPDADPAMFTPSFFAGVAAAAVSGYAV
IAALLRYLQRGSYLVFAWYRGLVAAVTVALLLARGM
>Mature_276_residues
MLFIGKTTEGFPVTVLQAVILGIVQGLAEFLPISSSAHLILVPWFLGWSPSGLAFDLALHVGTLIAVTIYFWRDLLNLAV
EGLTKGMKTPTGRLAWGIVLGTVPGAIFGLLMEDVVEAVFRQSILTIALLLAVVGVILYLADRFGPKRRSLEEIRVSDVI
WIGLAQALAVIPGVSRSGATITAGLALGLKRETAAKVSFLLGWPIILGGAVLVIPDADPAMFTPSFFAGVAAAAVSGYAV
IAALLRYLQRGSYLVFAWYRGLVAAVTVALLLARGM

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=272, Percent_Identity=33.4558823529412, Blast_Score=131, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_SYMTH (Q67LG6)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076324.1
- GeneID:   2982447
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH2495
- NMPDR:   fig|292459.1.peg.2387
- HOGENOM:   HBG391969
- OMA:   MFAVIVY
- BioCyc:   STHE292459:STH2495-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29199; Mature: 29199

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x143423fc)-; HASH(0x14edc05c)-; HASH(0x144dd4ac)-; HASH(0x13ee3fb0)-; HASH(0x1419c7c8)-; HASH(0x148708a8)-; HASH(0x1488e3c8)-; HASH(0x1440fef4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFIGKTTEGFPVTVLQAVILGIVQGLAEFLPISSSAHLILVPWFLGWSPSGLAFDLALH
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHH
VGTLIAVTIYFWRDLLNLAVEGLTKGMKTPTGRLAWGIVLGTVPGAIFGLLMEDVVEAVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQSILTIALLLAVVGVILYLADRFGPKRRSLEEIRVSDVIWIGLAQALAVIPGVSRSGAT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
ITAGLALGLKRETAAKVSFLLGWPIILGGAVLVIPDADPAMFTPSFFAGVAAAAVSGYAV
EEHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
IAALLRYLQRGSYLVFAWYRGLVAAVTVALLLARGM
HHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLFIGKTTEGFPVTVLQAVILGIVQGLAEFLPISSSAHLILVPWFLGWSPSGLAFDLALH
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHH
VGTLIAVTIYFWRDLLNLAVEGLTKGMKTPTGRLAWGIVLGTVPGAIFGLLMEDVVEAVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQSILTIALLLAVVGVILYLADRFGPKRRSLEEIRVSDVIWIGLAQALAVIPGVSRSGAT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
ITAGLALGLKRETAAKVSFLLGWPIILGGAVLVIPDADPAMFTPSFFAGVAAAAVSGYAV
EEHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
IAALLRYLQRGSYLVFAWYRGLVAAVTVALLLARGM
HHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA