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The map label for this gene is gamP [H]

Identifier: 51893586

GI number: 51893586

Start: 2634792

End: 2636270

Strand: Reverse

Name: gamP [H]

Synonym: STH2448

Alternate gene names: 51893586

Gene position: 2636270-2634792 (Counterclockwise)

Preceding gene: 51893587

Following gene: 51893585

Centisome position: 73.93

GC content: 73.7

Gene sequence:

>1479_bases
GTGCGAGAGAAGGCGGCGTTCTTCCAGCGGGCCTCGGCCAGCCTGATGGTTCCCCTGACCTTCGTGCCGCTCCCGGCGGT
GCTGGTGGCCCTGGGAACCGTCCTGGGGATCGGCCCGCTGGAGTCGGCGGGGCTGGAGCTGCTGCGGGTGTGGCTGCCGC
TGTTCTTCGCGATGGGCATCGCCGTGGGCTTCGCCCAGGCCGAGGGTATGGCGGTGCTCTCCGCCGCCGCCGGGTACCTG
ACGATGATGGCCGTGGCGGAGGGCGTGGCCGGCGATCCGGCGGTGAACTTCGGGGCCCTGGGCGGGGTGGCGGTCGGCGC
CGCCGCCGTCTGGCTGTACCGGTACGCGGCGAAGGTCAGGTTGCCCGAGTTCCTCGCGCTCTTTTCGGGCCGGCGGCTGG
GGCCGATCCTGGCGGCCCTGGCCGGGGTGGTCCTGGGCTGGGGGTTCGGCCTCGTGTGGCCGGGCTTCCACCGGGCCGTC
GTCCTGCTGGGCGAGTGGATCTACGCCGCCGGCGGCGCCGGGGCGTTCGTCTACGGCGGCATCATCCGGATGCTCATCCC
CACCGGCCTGCACCACCTCCTGATGCAGCTCATGGACTACCAGATGGGCGCGTGGACCGACCCGGCCACAGGCCAGGTGG
TGATGGGCGAGTACATCCGTTTCCTGCACGGCGATCCCAGCGCGGGGCGGCTGCTCTCCGGGTTCTTCCTCACCCTGGCC
TTCGGGCCGCTGGGCGCCGCCCTGGCGATGGTGCACGAGGCCCGGCCCGAGCAGCGCCGCCGGGTGAGCGGGATGATGCT
CACCGGCGTGCTCACGGCCATGGTGCTGGGCATCACGGAGCCGATCGAGTTCGCCTTCATCTTCGCCTCCCCGCTCCTGT
TCGGGATCCACGTGCTCTTTTCGGCCGCGGCCTCTCTGCTGGGGTACGTGCTGGACATCCACCTGGGGGGGTACGCCCTG
CCCCTGGCGGTCGTCAACTGGCACCGGCAGCAGAACGGCTGGCTGCTCCTGCCCCTGGGGGCGGCCTGGACGGCGCTCTA
CTACGTCACCTTCCGTCTGATCATCCGGTGGCGGCGGCCGCCGGTGCTGGGACAGACCGACGCCGTCCCCGTGGCGGGCG
CCGGGGGTTCGGACGCCCGGGCGGCCGCAGGGGAGCCGTCAGAGGCGGCGCGTCCGGCCGGGGCCGCTGGGCCTTCGGCG
GCCGCCATTCTGGATGCCCTGGGCGGGCCGGCCAACGTGCGCAGCCTCACCGCCTGCATGACCCGGCTGCGGCTGGAGGT
CAACGATCCCGCAGCGGTGGATGACGCCGCGCTGCGCGCCTTCGGCGCGGCCGGGGTGGTGCGGTCCGGGTCCTCCGTCC
AGGTGGTGATGGGCGCCCGGGCCGGCGACATCGAGCAGGCCCTGCAGGCCGAACTGGCGGAGGCGGCGGGGCAGGGCGGA
GCCGGGCAGACCGCGGGGAGGCAGGAGCCGTGCAGGTGA

Upstream 100 bases:

>100_bases
CCGCGCTGACCTCCCCCGCCGCCCGGGAGCGGGTGCAGGCGCGTGGGATCCGGCTGATGCACTTCGGCGACCTGACCGAC
GCAGCGAGGGGGTAAGTGTC

Downstream 100 bases:

>100_bases
CGATGGCGGTCGCCAAGGTGCCGAAGTTTGGATTGGTGGAAAGTGGGGATTCTGTAGAACTGTTGGAGCGTCCCCGCGGC
GGCCTCACCGCCATTCTGGC

Product: PTS system N-acetylglucosamine-specific enzyme IIABC component

Products: NA

Alternate protein names: Glucosamine permease IIC component; PTS system glucosamine-specific EIIC component; Glucosamine-specific phosphotransferase enzyme IIB component; PTS system glucosamine-specific EIIB component; Glucosamine-specific phosphotransferase enzyme IIA component; PTS system glucosamine-specific EIIA component [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MREKAAFFQRASASLMVPLTFVPLPAVLVALGTVLGIGPLESAGLELLRVWLPLFFAMGIAVGFAQAEGMAVLSAAAGYL
TMMAVAEGVAGDPAVNFGALGGVAVGAAAVWLYRYAAKVRLPEFLALFSGRRLGPILAALAGVVLGWGFGLVWPGFHRAV
VLLGEWIYAAGGAGAFVYGGIIRMLIPTGLHHLLMQLMDYQMGAWTDPATGQVVMGEYIRFLHGDPSAGRLLSGFFLTLA
FGPLGAALAMVHEARPEQRRRVSGMMLTGVLTAMVLGITEPIEFAFIFASPLLFGIHVLFSAAASLLGYVLDIHLGGYAL
PLAVVNWHRQQNGWLLLPLGAAWTALYYVTFRLIIRWRRPPVLGQTDAVPVAGAGGSDARAAAGEPSEAARPAGAAGPSA
AAILDALGGPANVRSLTACMTRLRLEVNDPAAVDDAALRAFGAAGVVRSGSSVQVVMGARAGDIEQALQAELAEAAGQGG
AGQTAGRQEPCR

Sequences:

>Translated_492_residues
MREKAAFFQRASASLMVPLTFVPLPAVLVALGTVLGIGPLESAGLELLRVWLPLFFAMGIAVGFAQAEGMAVLSAAAGYL
TMMAVAEGVAGDPAVNFGALGGVAVGAAAVWLYRYAAKVRLPEFLALFSGRRLGPILAALAGVVLGWGFGLVWPGFHRAV
VLLGEWIYAAGGAGAFVYGGIIRMLIPTGLHHLLMQLMDYQMGAWTDPATGQVVMGEYIRFLHGDPSAGRLLSGFFLTLA
FGPLGAALAMVHEARPEQRRRVSGMMLTGVLTAMVLGITEPIEFAFIFASPLLFGIHVLFSAAASLLGYVLDIHLGGYAL
PLAVVNWHRQQNGWLLLPLGAAWTALYYVTFRLIIRWRRPPVLGQTDAVPVAGAGGSDARAAAGEPSEAARPAGAAGPSA
AAILDALGGPANVRSLTACMTRLRLEVNDPAAVDDAALRAFGAAGVVRSGSSVQVVMGARAGDIEQALQAELAEAAGQGG
AGQTAGRQEPCR
>Mature_492_residues
MREKAAFFQRASASLMVPLTFVPLPAVLVALGTVLGIGPLESAGLELLRVWLPLFFAMGIAVGFAQAEGMAVLSAAAGYL
TMMAVAEGVAGDPAVNFGALGGVAVGAAAVWLYRYAAKVRLPEFLALFSGRRLGPILAALAGVVLGWGFGLVWPGFHRAV
VLLGEWIYAAGGAGAFVYGGIIRMLIPTGLHHLLMQLMDYQMGAWTDPATGQVVMGEYIRFLHGDPSAGRLLSGFFLTLA
FGPLGAALAMVHEARPEQRRRVSGMMLTGVLTAMVLGITEPIEFAFIFASPLLFGIHVLFSAAASLLGYVLDIHLGGYAL
PLAVVNWHRQQNGWLLLPLGAAWTALYYVTFRLIIRWRRPPVLGQTDAVPVAGAGGSDARAAAGEPSEAARPAGAAGPSA
AAILDALGGPANVRSLTACMTRLRLEVNDPAAVDDAALRAFGAAGVVRSGSSVQVVMGARAGDIEQALQAELAEAAGQGG
AGQTAGRQEPCR

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=493, Percent_Identity=32.2515212981744, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1786894, Length=487, Percent_Identity=34.2915811088296, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1787908, Length=525, Percent_Identity=31.4285714285714, Blast_Score=199, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51118; Mature: 51118

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 7751298 [H]