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The map label for this gene is secDF [H]

Identifier: 51893580

GI number: 51893580

Start: 2630036

End: 2630962

Strand: Reverse

Name: secDF [H]

Synonym: STH2442

Alternate gene names: 51893580

Gene position: 2630962-2630036 (Counterclockwise)

Preceding gene: 51893581

Following gene: 51893579

Centisome position: 73.78

GC content: 67.64

Gene sequence:

>927_bases
ATGGGCCTTACCCGCATCCGCTACATGCGCTATGCCCGCCACTACCTCATCTTCACCCTGGTGACCGTGCTGCTGGCCGC
CGGCGCGCTGCTCTTCCGGGGGCTGAACCTGGGCATCGACTTCACGGGCGGCCTGCTGCTGGACCTGCAGTTTGAGCGCA
CGGTCACGATCGAGCAGGTGCGCACCGTGATCGACAGCGCGCTCGGCATCGACGCGCAGATCCAGCAGGTGGAGCCCAAG
GGGGCGGCGAGCCCCGAGGCCACCGAGTTCCTCGTGCGCACGCCCGAACTGAGCGCCGAGGACAAGGACAGGCTCTACGG
CAGCCTCCTGCACCTGGGGGCGTACACCGTCATCGGCGAGGACGCGGTCTCGGGGACGGTCTCCTCCGAGCTGACGAACA
AGGCCCTGCTGGCCGTGGGCATCGCCGCGGTGCTGCAGGTGATCTACATCTCCATCCGGTTCCAGTTCCGCATGGGGGTC
GCAGCGGTCGTCGCCCTGCTGCACGACGTGCTCCTCACCATGGGCGTGCTGGCGCTGTTCCAGGTGGAGATCAGCTCCAA
CTTCGTGGCGGCCATCCTCACGGTGCTGGGCTATTCGATGAACGACACCGTGGTGGTCCTGGACCGGCTGCGGGAGAACC
TGCACAGCCGGCAGAAGGGCGAGTCGCTGGAGGAGATGGCGACCCGGTCGATTCAGGAGGTCATCACCCGGTCCATCTAC
ACCGGCGTATCGGTGCAGCTCATGCTGCTGGCGATGATCTTCCTGGGCGGGTCGACGGTTCTGGACCTGGCCTCCACGCT
GTTCGTCGGCATCCTCGCCGGCACATACTCCTCCATCACCGTCGCGGCCGCGCTCTGGTTCGTGTGGGAGCAAAGCCGGG
AAGGCGGCCACCCCGGGCCTGCCGGCGCCAGGCCGGCCAGGGCGTAG

Upstream 100 bases:

>100_bases
CACGGCCATCACCTTCACCCGCTGGCTGGTCAAGCTCGCGGTGGACACCGGCTGGTTCAACAAGCGGACGCTGTTCGGCG
TGAAGGAGGTGGCCAACTAG

Downstream 100 bases:

>100_bases
CCGGGGGGCCGGAGCCCGGTGGTCGGCGGAGGCGCAGGATTCGACATACAGAGCAACACGGGGCGCCCTTTCGGGGGCGC
CCTTTCGACATTGTCGGCGC

Product: protein translocase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MGLTRIRYMRYARHYLIFTLVTVLLAAGALLFRGLNLGIDFTGGLLLDLQFERTVTIEQVRTVIDSALGIDAQIQQVEPK
GAASPEATEFLVRTPELSAEDKDRLYGSLLHLGAYTVIGEDAVSGTVSSELTNKALLAVGIAAVLQVIYISIRFQFRMGV
AAVVALLHDVLLTMGVLALFQVEISSNFVAAILTVLGYSMNDTVVVLDRLRENLHSRQKGESLEEMATRSIQEVITRSIY
TGVSVQLMLLAMIFLGGSTVLDLASTLFVGILAGTYSSITVAAALWFVWEQSREGGHPGPAGARPARA

Sequences:

>Translated_308_residues
MGLTRIRYMRYARHYLIFTLVTVLLAAGALLFRGLNLGIDFTGGLLLDLQFERTVTIEQVRTVIDSALGIDAQIQQVEPK
GAASPEATEFLVRTPELSAEDKDRLYGSLLHLGAYTVIGEDAVSGTVSSELTNKALLAVGIAAVLQVIYISIRFQFRMGV
AAVVALLHDVLLTMGVLALFQVEISSNFVAAILTVLGYSMNDTVVVLDRLRENLHSRQKGESLEEMATRSIQEVITRSIY
TGVSVQLMLLAMIFLGGSTVLDLASTLFVGILAGTYSSITVAAALWFVWEQSREGGHPGPAGARPARA
>Mature_307_residues
GLTRIRYMRYARHYLIFTLVTVLLAAGALLFRGLNLGIDFTGGLLLDLQFERTVTIEQVRTVIDSALGIDAQIQQVEPKG
AASPEATEFLVRTPELSAEDKDRLYGSLLHLGAYTVIGEDAVSGTVSSELTNKALLAVGIAAVLQVIYISIRFQFRMGVA
AVVALLHDVLLTMGVLALFQVEISSNFVAAILTVLGYSMNDTVVVLDRLRENLHSRQKGESLEEMATRSIQEVITRSIYT
GVSVQLMLLAMIFLGGSTVLDLASTLFVGILAGTYSSITVAAALWFVWEQSREGGHPGPAGARPARA

Specific function: Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane [H]

COG id: COG0341

COG function: function code U; Preprotein translocase subunit SecF

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786610, Length=301, Percent_Identity=30.5647840531561, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 33303; Mature: 33172

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTRIRYMRYARHYLIFTLVTVLLAAGALLFRGLNLGIDFTGGLLLDLQFERTVTIEQV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCHHHHHHH
RTVIDSALGIDAQIQQVEPKGAASPEATEFLVRTPELSAEDKDRLYGSLLHLGAYTVIGE
HHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHEECC
DAVSGTVSSELTNKALLAVGIAAVLQVIYISIRFQFRMGVAAVVALLHDVLLTMGVLALF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVEISSNFVAAILTVLGYSMNDTVVVLDRLRENLHSRQKGESLEEMATRSIQEVITRSIY
HHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TGVSVQLMLLAMIFLGGSTVLDLASTLFVGILAGTYSSITVAAALWFVWEQSREGGHPGP
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGARPARA
CCCCCCCC
>Mature Secondary Structure 
GLTRIRYMRYARHYLIFTLVTVLLAAGALLFRGLNLGIDFTGGLLLDLQFERTVTIEQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCHHHHHHH
RTVIDSALGIDAQIQQVEPKGAASPEATEFLVRTPELSAEDKDRLYGSLLHLGAYTVIGE
HHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHEECC
DAVSGTVSSELTNKALLAVGIAAVLQVIYISIRFQFRMGVAAVVALLHDVLLTMGVLALF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVEISSNFVAAILTVLGYSMNDTVVVLDRLRENLHSRQKGESLEEMATRSIQEVITRSIY
HHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TGVSVQLMLLAMIFLGGSTVLDLASTLFVGILAGTYSSITVAAALWFVWEQSREGGHPGP
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGARPARA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9694879; 9384377 [H]