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The map label for this gene is aseR [H]

Identifier: 51893508

GI number: 51893508

Start: 2559799

End: 2560116

Strand: Reverse

Name: aseR [H]

Synonym: STH2370

Alternate gene names: 51893508

Gene position: 2560116-2559799 (Counterclockwise)

Preceding gene: 51893509

Following gene: 51893507

Centisome position: 71.79

GC content: 64.47

Gene sequence:

>318_bases
ATGGAGCGGCACGTGATCCTGATGAAGGCGCTGGGAGACTTGACGCGCCTGAAAATCCTGAAGTTGATCTGGGACCGGGA
GCGGTGCGTGTGCGAGCTCTATCCGGTCCTCGGCATCAGCCAGCCCGCGGTTTCCCAGCACATCGCCAAGCTGAAGGCGG
CCGGCCTGGTCCGTGAACGCAGAGCGGGGATGTGGGTGTACTACCAGGCCGACCGCGAGCGGCTCCTGGAAGGGTTGAAG
GCGTTTCGGGCTTTCCTGGACGCGGACCTCACGACCATCCCGGAACTGTGCGGGGTTGATGGCCGGGGGTGTTGCTGA

Upstream 100 bases:

>100_bases
CGATGGCCCACGCACGCCCGCTGCTGCCAGCCGGATGAGAAAACGCGGTTGGTATCAAGAAGGACATAACCATATACTTA
TATAGCAGGGAGGGCGTCGG

Downstream 100 bases:

>100_bases
AGGCGTCCAAGCCGGACGTCGGTTGTCGTCGTTGGAGCCGCTGACCCGGGGGCGCTGCCGGCCGGGAGGCGGCTTCGGGC
ATGGGGGCTGCAGGAAATCA

Product: transcription regulator ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MERHVILMKALGDLTRLKILKLIWDRERCVCELYPVLGISQPAVSQHIAKLKAAGLVRERRAGMWVYYQADRERLLEGLK
AFRAFLDADLTTIPELCGVDGRGCC

Sequences:

>Translated_105_residues
MERHVILMKALGDLTRLKILKLIWDRERCVCELYPVLGISQPAVSQHIAKLKAAGLVRERRAGMWVYYQADRERLLEGLK
AFRAFLDADLTTIPELCGVDGRGCC
>Mature_105_residues
MERHVILMKALGDLTRLKILKLIWDRERCVCELYPVLGISQPAVSQHIAKLKAAGLVRERRAGMWVYYQADRERLLEGLK
AFRAFLDADLTTIPELCGVDGRGCC

Specific function: Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11943; Mature: 11943

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERHVILMKALGDLTRLKILKLIWDRERCVCELYPVLGISQPAVSQHIAKLKAAGLVRER
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RAGMWVYYQADRERLLEGLKAFRAFLDADLTTIPELCGVDGRGCC
HCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MERHVILMKALGDLTRLKILKLIWDRERCVCELYPVLGISQPAVSQHIAKLKAAGLVRER
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RAGMWVYYQADRERLLEGLKAFRAFLDADLTTIPELCGVDGRGCC
HCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]