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The map label for this gene is ydbM [H]

Identifier: 51893495

GI number: 51893495

Start: 2546560

End: 2547765

Strand: Reverse

Name: ydbM [H]

Synonym: STH2357

Alternate gene names: 51893495

Gene position: 2547765-2546560 (Counterclockwise)

Preceding gene: 51893496

Following gene: 51893494

Centisome position: 71.44

GC content: 73.88

Gene sequence:

>1206_bases
ATGGCCGTCCCGGAACCAGACCTCTTCGTGCGGACCGAGCGGCAGAGGCGGTTCGTCGCCCTGGCTGGCGAGCTGGCCGA
CCGGTTCGCCGGGCGGGCGGCGCTGCACGACCGGGAGAACTCGTTCCCGTTCGAGAACTTCGCAGAACTGCGGGCCTCGG
GGTACGTCCGCCTCACGGTGCCGGTCGAGTGGGGCGGCGAGGGGGCGAACCTGACCGAGACCCTGCTCGCGCAGGAGCGG
CTGGCCCAGGGCGACGGCGCCACGGCCCTGGGCATCGGGTGGCATCTGGCCGTGGTCGGCAAGCTGGCGGAGACCCGGGC
CTGGCCGCCGGCGGCGACCGCGCGGATCTTCCGTGAAGTGGCCGGGCGGGGGGCGCTGATCAACTCTGCCGCCAGCGAGG
TGGAGACCGGAAGCCCCTCCCGGGGAGGCCGGCCCACCACGACGGCCCGGCGCGCGCCGGGGGGCTGGCTGCTGACGGGG
CGCAAATCGTTCACCTCCCTGGCGCCGGTCCTCGACTACGCCGTGGTCTCGGCCAGCTTCGAAGGGTCCGACGGGGGCGG
CTGGTTCCTGGTGCAGACGGGCAGCCCGGGCGTGACCGTCGTCGAGACCTGGGATGCGTTGGGCATGCGGGCCACCGGCA
GCCACGACCTGGTCCTGGAGGACGTGTTCGTGGAGGACGGCGACCTCCTGGAGACCTTCGGCCGGGGCAACACCTGCCAG
GTGGGCACGGGGGACGGCGCCGGGTGGGCCCTGCACATCCCCGCCGTGTATCTGGGCATCGCCCGGGCCGCCCACGGGTT
CGCCGTGGAGTACGCCCGGACCCGCCGCCCCAACTCGCTGCCCGGCCCGATCGCCGACCAGCCCCACATCCAGGCGCTGC
TCGGCCAGAACGAGATCGACCTTCTGGCGGCCCGCTCCGCCCTCTACACGGTAGCGGACCGCTGGGACGCCGAGCCGGAG
CGGCGCGGCGAGCTGGTCCCCCTGCTGGGCGCCGCCAAGGTGCTGGCCGTGAACCTCGCCCTGCAGATCGTCGACCGGGC
GATGCGGGTGGCGGGCATCGCCGGTCTCTTCCGGCAACTGCCCTTGGAGCGGCTCTACCGTGACGTGCGGGCGGGCCTGC
ACAACCCGCCGATGGAGGATGCCGTGCTCCGGAACCTCGCACGGGCGGCGCTCGCCCGGCAGGCTTCCGCTGCAGCCATC
TCATAG

Upstream 100 bases:

>100_bases
CGGGGCCGGCGGGCCTGAGAGGGGATCGGTGTGACGTTGCTGACCGATCTGGGGGGCGGTGAGGATGACGGACAAGGTGA
GTTCCGGAGGAGGGGCCGGC

Downstream 100 bases:

>100_bases
GAAAGGGGTCGGGTTATGGCGATCACGCATATTGACCATGTGCTGATCGCGGTGAACGGTCTGGAGGAGGCGGCCGAGCG
GTACCGCCGGCTCGGGTTCT

Product: acyl-CoA dehydrogenase, short-chain specific

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MAVPEPDLFVRTERQRRFVALAGELADRFAGRAALHDRENSFPFENFAELRASGYVRLTVPVEWGGEGANLTETLLAQER
LAQGDGATALGIGWHLAVVGKLAETRAWPPAATARIFREVAGRGALINSAASEVETGSPSRGGRPTTTARRAPGGWLLTG
RKSFTSLAPVLDYAVVSASFEGSDGGGWFLVQTGSPGVTVVETWDALGMRATGSHDLVLEDVFVEDGDLLETFGRGNTCQ
VGTGDGAGWALHIPAVYLGIARAAHGFAVEYARTRRPNSLPGPIADQPHIQALLGQNEIDLLAARSALYTVADRWDAEPE
RRGELVPLLGAAKVLAVNLALQIVDRAMRVAGIAGLFRQLPLERLYRDVRAGLHNPPMEDAVLRNLARAALARQASAAAI
S

Sequences:

>Translated_401_residues
MAVPEPDLFVRTERQRRFVALAGELADRFAGRAALHDRENSFPFENFAELRASGYVRLTVPVEWGGEGANLTETLLAQER
LAQGDGATALGIGWHLAVVGKLAETRAWPPAATARIFREVAGRGALINSAASEVETGSPSRGGRPTTTARRAPGGWLLTG
RKSFTSLAPVLDYAVVSASFEGSDGGGWFLVQTGSPGVTVVETWDALGMRATGSHDLVLEDVFVEDGDLLETFGRGNTCQ
VGTGDGAGWALHIPAVYLGIARAAHGFAVEYARTRRPNSLPGPIADQPHIQALLGQNEIDLLAARSALYTVADRWDAEPE
RRGELVPLLGAAKVLAVNLALQIVDRAMRVAGIAGLFRQLPLERLYRDVRAGLHNPPMEDAVLRNLARAALARQASAAAI
S
>Mature_400_residues
AVPEPDLFVRTERQRRFVALAGELADRFAGRAALHDRENSFPFENFAELRASGYVRLTVPVEWGGEGANLTETLLAQERL
AQGDGATALGIGWHLAVVGKLAETRAWPPAATARIFREVAGRGALINSAASEVETGSPSRGGRPTTTARRAPGGWLLTGR
KSFTSLAPVLDYAVVSASFEGSDGGGWFLVQTGSPGVTVVETWDALGMRATGSHDLVLEDVFVEDGDLLETFGRGNTCQV
GTGDGAGWALHIPAVYLGIARAAHGFAVEYARTRRPNSLPGPIADQPHIQALLGQNEIDLLAARSALYTVADRWDAEPER
RGELVPLLGAAKVLAVNLALQIVDRAMRVAGIAGLFRQLPLERLYRDVRAGLHNPPMEDAVLRNLARAALARQASAAAIS

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=348, Percent_Identity=27.5862068965517, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=24.6684350132626, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI7656849, Length=369, Percent_Identity=23.5772357723577, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4501859, Length=330, Percent_Identity=24.8484848484848, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=381, Percent_Identity=23.8845144356955, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=344, Percent_Identity=26.1627906976744, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=26.7195767195767, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24666513, Length=346, Percent_Identity=24.8554913294798, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356377, Length=355, Percent_Identity=24.7887323943662, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355753, Length=343, Percent_Identity=25.6559766763848, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24660351, Length=384, Percent_Identity=23.9583333333333, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42748; Mature: 42617

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPEPDLFVRTERQRRFVALAGELADRFAGRAALHDRENSFPFENFAELRASGYVRLTV
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHCCEEEEEE
PVEWGGEGANLTETLLAQERLAQGDGATALGIGWHLAVVGKLAETRAWPPAATARIFREV
EEEECCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AGRGALINSAASEVETGSPSRGGRPTTTARRAPGGWLLTGRKSFTSLAPVLDYAVVSASF
HCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCC
EGSDGGGWFLVQTGSPGVTVVETWDALGMRATGSHDLVLEDVFVEDGDLLETFGRGNTCQ
CCCCCCCEEEEEECCCCEEEEEEHHHCCCCCCCCCCEEEEEEECCCCHHHHHCCCCCEEE
VGTGDGAGWALHIPAVYLGIARAAHGFAVEYARTRRPNSLPGPIADQPHIQALLGQNEID
ECCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCHH
LLAARSALYTVADRWDAEPERRGELVPLLGAAKVLAVNLALQIVDRAMRVAGIAGLFRQL
HHHHHHHHHHHHHHCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLERLYRDVRAGLHNPPMEDAVLRNLARAALARQASAAAIS
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVPEPDLFVRTERQRRFVALAGELADRFAGRAALHDRENSFPFENFAELRASGYVRLTV
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHCCEEEEEE
PVEWGGEGANLTETLLAQERLAQGDGATALGIGWHLAVVGKLAETRAWPPAATARIFREV
EEEECCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AGRGALINSAASEVETGSPSRGGRPTTTARRAPGGWLLTGRKSFTSLAPVLDYAVVSASF
HCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCC
EGSDGGGWFLVQTGSPGVTVVETWDALGMRATGSHDLVLEDVFVEDGDLLETFGRGNTCQ
CCCCCCCEEEEEECCCCEEEEEEHHHCCCCCCCCCCEEEEEEECCCCHHHHHCCCCCEEE
VGTGDGAGWALHIPAVYLGIARAAHGFAVEYARTRRPNSLPGPIADQPHIQALLGQNEID
ECCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCHH
LLAARSALYTVADRWDAEPERRGELVPLLGAAKVLAVNLALQIVDRAMRVAGIAGLFRQL
HHHHHHHHHHHHHHCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLERLYRDVRAGLHNPPMEDAVLRNLARAALARQASAAAIS
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]