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The map label for this gene is kaiC [H]

Identifier: 51893493

GI number: 51893493

Start: 2544085

End: 2545485

Strand: Reverse

Name: kaiC [H]

Synonym: STH2355

Alternate gene names: 51893493

Gene position: 2545485-2544085 (Counterclockwise)

Preceding gene: 51893494

Following gene: 51893492

Centisome position: 71.38

GC content: 69.88

Gene sequence:

>1401_bases
GTGCACGCCAGACTGTCCACCGGAGTTGAGGGGCTCGACAGCGTGCTCGGCGGCGGCCTGTTTCCGGCGAGCGCCACGCT
GGTGCGGGGCGCGCCGGGGACCGGCAAGACGACCCTGGGGATCCAGTTCCTTTGCGAGGGTGCCCGCCGGGGCGAGGGGG
GTGCGTACTTCACCTTCGAGGAGTTCCCGGAGCAGATCTACCGGGACGCCCGCGAGCTGGGGTTTGATCTGCAGGCCCTG
GAGCAGGCGGGGAAGCTGCAGGTCATCACCCTGGATCCCGGTGCCTTCCTGGATGAGGCGATCCGGCCGGGTGGCCTCCT
GGAGGAGCTGAAGCGGGAGATCGGCCTCCGCCGGGTGGTCGTGGACAGCGTTACCCTGTTGGAACTGGCCCTGGCGGAAA
AGGGCGGTCGGCGAACGCTCTACCTGCTCCGCAACGCCCTGCACCGGATGGGGGCCACCAGCCTTCTCGTGGAAGAAGGG
GCGCCGGCGGAGGGCCCGTCTGCGGCCGAGTACATGGTGGACACCGTTCTTCACCTGACGTACGACGACTTCGAGGTGAA
CCGGCTCCGCCACCTGGAGGTGCGCAAGCACAGGGGCTCCCCGTTCCGCACCGGAAAGCACGTCTTCGTCATCTCCCGGC
GGGGGATCCGGGTGCTGCCCGCCCTGGACCGGGTGCCGGACCTGACCGTGGGCGAGGTGGTGCCCACTGGCCTGGACCGG
CTGGACGAGTGCCTGGGCGGCGGCATCCCCCGGGGGAGCACGTTGGTCCTCAACGTCAACAGCAAGTGCAACTACCGCTA
CCTGCTCGGGGCGATCGCCGCTGCGCACCTCCGGCAGGGCGACGGTTACGTCGCCGTGTGCTCGGCCGTGCGGCCGCCGG
CAGTGGTCGCGATGGTGCTGAGCCTCTACGGCTTCGACGCCGCCCGGCTGGGGGCCGAGGGCCGGTGGCGGTACATCGAG
CAGGAGGGGCGGCCGGTTCCGCCGGAGCTGGAACCCTACATTATCCGGGTGTCCAACGAGTTCGACCTGTTCGTGTCGCC
GGGGAGCGCCACCGCCATCGCCCACGGCATCGGCAGCCCCGACGGCCCGCGCCACTGGCTCTGGTCCCTCGACCTGAACG
CCGCCCTGCACACCCTGAAGCAGGACGCGGTGGTGAAAGGCTGGGCGGAGGCCATCTCCCACGCCCGGCACCGGGGCGAC
ACCATCGTCGGCATCTGCAACTTCGAGGAGATGGGGCCGGCGATGTCCGCCTTCGTCCAGCGCAATGCGGAGGGCATCCT
GCGGACCTGGTTCGACGGGCGGTACCAGTACCTGCAGGTACAGAAAGCGCCCAACGGCCGCGTGTCGGAGCTGATGGTCA
TCGAGTACACCGACGCGCCCCCGTACCTGGCGCTGTGGTAG

Upstream 100 bases:

>100_bases
CCCAAAGGTGCCTGCGGCGGCCCGATGCGTCCGGCATCCGTGCAGCGCGACCGGGTACGGCGAAACCGGCACATGAATGG
TGGGGAGAGCCGTGAGCGAA

Downstream 100 bases:

>100_bases
GGGAGGTGCGGCAGATGACTGCAGACCTGAACGCCGTTCGACTGGAGGCCGCCCTCTACTTCCAGCGCAACCCCTTCGCG
CGGGAGACGCCCGAGAGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MHARLSTGVEGLDSVLGGGLFPASATLVRGAPGTGKTTLGIQFLCEGARRGEGGAYFTFEEFPEQIYRDARELGFDLQAL
EQAGKLQVITLDPGAFLDEAIRPGGLLEELKREIGLRRVVVDSVTLLELALAEKGGRRTLYLLRNALHRMGATSLLVEEG
APAEGPSAAEYMVDTVLHLTYDDFEVNRLRHLEVRKHRGSPFRTGKHVFVISRRGIRVLPALDRVPDLTVGEVVPTGLDR
LDECLGGGIPRGSTLVLNVNSKCNYRYLLGAIAAAHLRQGDGYVAVCSAVRPPAVVAMVLSLYGFDAARLGAEGRWRYIE
QEGRPVPPELEPYIIRVSNEFDLFVSPGSATAIAHGIGSPDGPRHWLWSLDLNAALHTLKQDAVVKGWAEAISHARHRGD
TIVGICNFEEMGPAMSAFVQRNAEGILRTWFDGRYQYLQVQKAPNGRVSELMVIEYTDAPPYLALW

Sequences:

>Translated_466_residues
MHARLSTGVEGLDSVLGGGLFPASATLVRGAPGTGKTTLGIQFLCEGARRGEGGAYFTFEEFPEQIYRDARELGFDLQAL
EQAGKLQVITLDPGAFLDEAIRPGGLLEELKREIGLRRVVVDSVTLLELALAEKGGRRTLYLLRNALHRMGATSLLVEEG
APAEGPSAAEYMVDTVLHLTYDDFEVNRLRHLEVRKHRGSPFRTGKHVFVISRRGIRVLPALDRVPDLTVGEVVPTGLDR
LDECLGGGIPRGSTLVLNVNSKCNYRYLLGAIAAAHLRQGDGYVAVCSAVRPPAVVAMVLSLYGFDAARLGAEGRWRYIE
QEGRPVPPELEPYIIRVSNEFDLFVSPGSATAIAHGIGSPDGPRHWLWSLDLNAALHTLKQDAVVKGWAEAISHARHRGD
TIVGICNFEEMGPAMSAFVQRNAEGILRTWFDGRYQYLQVQKAPNGRVSELMVIEYTDAPPYLALW
>Mature_466_residues
MHARLSTGVEGLDSVLGGGLFPASATLVRGAPGTGKTTLGIQFLCEGARRGEGGAYFTFEEFPEQIYRDARELGFDLQAL
EQAGKLQVITLDPGAFLDEAIRPGGLLEELKREIGLRRVVVDSVTLLELALAEKGGRRTLYLLRNALHRMGATSLLVEEG
APAEGPSAAEYMVDTVLHLTYDDFEVNRLRHLEVRKHRGSPFRTGKHVFVISRRGIRVLPALDRVPDLTVGEVVPTGLDR
LDECLGGGIPRGSTLVLNVNSKCNYRYLLGAIAAAHLRQGDGYVAVCSAVRPPAVVAMVLSLYGFDAARLGAEGRWRYIE
QEGRPVPPELEPYIIRVSNEFDLFVSPGSATAIAHGIGSPDGPRHWLWSLDLNAALHTLKQDAVVKGWAEAISHARHRGD
TIVGICNFEEMGPAMSAFVQRNAEGILRTWFDGRYQYLQVQKAPNGRVSELMVIEYTDAPPYLALW

Specific function: Core component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by actin

COG id: COG0467

COG function: function code T; RecA-superfamily ATPases implicated in signal transduction

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 kaiC domains [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=224, Percent_Identity=29.9107142857143, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014774
- InterPro:   IPR013503
- InterPro:   IPR010624 [H]

Pfam domain/function: PF06745 KaiC [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 50987; Mature: 50987

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51146 KAIC ; PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHARLSTGVEGLDSVLGGGLFPASATLVRGAPGTGKTTLGIQFLCEGARRGEGGAYFTFE
CCCCHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEHHHHHCCCCCCCCCCEEEEHH
EFPEQIYRDARELGFDLQALEQAGKLQVITLDPGAFLDEAIRPGGLLEELKREIGLRRVV
HHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHHCCHHHH
VDSVTLLELALAEKGGRRTLYLLRNALHRMGATSLLVEEGAPAEGPSAAEYMVDTVLHLT
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHEE
YDDFEVNRLRHLEVRKHRGSPFRTGKHVFVISRRGIRVLPALDRVPDLTVGEVVPTGLDR
ECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCHHCCCCCCHHHHCCCHHHH
LDECLGGGIPRGSTLVLNVNSKCNYRYLLGAIAAAHLRQGDGYVAVCSAVRPPAVVAMVL
HHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
SLYGFDAARLGAEGRWRYIEQEGRPVPPELEPYIIRVSNEFDLFVSPGSATAIAHGIGSP
HHHCCCHHHCCCCCCEEEECCCCCCCCCCCCCEEEEECCCEEEEECCCCCCEEEECCCCC
DGPRHWLWSLDLNAALHTLKQDAVVKGWAEAISHARHRGDTIVGICNFEEMGPAMSAFVQ
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHCHHHHHHHH
RNAEGILRTWFDGRYQYLQVQKAPNGRVSELMVIEYTDAPPYLALW
HCCCHHHHHHHCCCEEEEEEEECCCCCCEEEEEEEECCCCCCEEEC
>Mature Secondary Structure
MHARLSTGVEGLDSVLGGGLFPASATLVRGAPGTGKTTLGIQFLCEGARRGEGGAYFTFE
CCCCHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEHHHHHCCCCCCCCCCEEEEHH
EFPEQIYRDARELGFDLQALEQAGKLQVITLDPGAFLDEAIRPGGLLEELKREIGLRRVV
HHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHHCCHHHH
VDSVTLLELALAEKGGRRTLYLLRNALHRMGATSLLVEEGAPAEGPSAAEYMVDTVLHLT
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHEE
YDDFEVNRLRHLEVRKHRGSPFRTGKHVFVISRRGIRVLPALDRVPDLTVGEVVPTGLDR
ECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCHHCCCCCCHHHHCCCHHHH
LDECLGGGIPRGSTLVLNVNSKCNYRYLLGAIAAAHLRQGDGYVAVCSAVRPPAVVAMVL
HHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
SLYGFDAARLGAEGRWRYIEQEGRPVPPELEPYIIRVSNEFDLFVSPGSATAIAHGIGSP
HHHCCCHHHCCCCCCEEEECCCCCCCCCCCCCEEEEECCCEEEEECCCCCCEEEECCCCC
DGPRHWLWSLDLNAALHTLKQDAVVKGWAEAISHARHRGDTIVGICNFEEMGPAMSAFVQ
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHCHHHHHHHH
RNAEGILRTWFDGRYQYLQVQKAPNGRVSELMVIEYTDAPPYLALW
HCCCHHHHHHHCCCEEEEEEEECCCCCCEEEEEEEECCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9727980; 12477935 [H]