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The map label for this gene is gerKB2 [H]

Identifier: 51893243

GI number: 51893243

Start: 2245872

End: 2246888

Strand: Reverse

Name: gerKB2 [H]

Synonym: STH2105

Alternate gene names: 51893243

Gene position: 2246888-2245872 (Counterclockwise)

Preceding gene: 51893244

Following gene: 51893242

Centisome position: 63.01

GC content: 66.76

Gene sequence:

>1017_bases
TTGCTGCTGGAAAGCGCCGGTCAGGAAGCCTGGATCACCGTGCTCATCCTGGGCGTGTACGCGCTGGTCGTTGCCCTGGC
GGTGGTCTGGATCGCCTGCCGCTTCCCTGACCGGGATCCCCTGAAGGCGATCCGGTGCACCCTGGGGTCCTGGGCAACCT
ACCCCATCGTCCTGCTGTACTGCGCGTTCAACGTGCTGATCTACGCCATGTCGCTCAGTGACGTGCAGACCTTCACCAAG
ATCCTCCTGCTGCCGGACACCCCGGCCTGGGTGTTGGCGGTCATGATTGCCCTGTTCACGATCTACACCGTGCTCCAGGG
GGTGGAGCCTATCGCCCGCACCGCCTACGGCGTGCTGGTGCCGCTCGTCCTGGTGATCCTCGTCCTGCCCTTCGGCGTGG
GGAAGGAGATCCGGCTGCTTCAGATCGATCCGTTCCTGTGGAAGGGGTTCTCCGGCGTCCTGCGCGGCGCGTGGCTCGCC
CTGCCCTGGGCGGGCCAGTCCCTCATCGTGCTCAGCCTCATGCGCCACCTGAGCCTCCGGGTGAACCCGTACAAGTGGAC
GCTGATCGGGGTGGGCAGCGCGCACCTCGCGCTGGCGATCATGGTCCTCCTGATCAGCCTGGTGTTCGGTTCGATCCTGC
CGTCTCGCCTTCTGTATCCGGGACACGAGCTGTTCGCGATCGTCGCGCTGACGGAGTCCATCGAGCGCATTCAGGCGGGA
ATCATGGTGCTCTGGCTCTGCGGCAGCTTGATCAACATCACGCTGCACCTGTACGTGGCGGTGGAGGAGGGCAGCCTGGC
GCTGGGGATTCAGCGGCGGGGATGGATCACGCTGATCCTGGGCGCGGCGGGGGTGTTCCTGGCGCAGTGGGCAGGCGGGG
CCCTGTACCGCCGGTCCATCGCCAGGGAGGCGTGGTGGATCGGGATGCACATCGCGGGGCAACTGGCCGTGCTGGCTCTG
CTGGGCCTGGCCACGCTCCTGATCCGCATGCGACAGGGGGCGGGGACGAGTGCGTAG

Upstream 100 bases:

>100_bases
AGGGAGGCCAAGCCCGGTGAAGATCTGGATCAGCGGCGGACTCTACGCTTCGGTGTTGGTTGTGACGCAGTTCATCATGC
AGTACGTGATGCTTCCCCGG

Downstream 100 bases:

>100_bases
GCGGATGCGGCTGCTGGCGCTGTCCGTGCTCCTGGCGCTCGGGTCGGCCCTGCTCTCGGGCTGCTGGAGCCGCGTCGAGC
TCAACGACATCGGCCTGGTG

Product: spore germination protein KB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLLESAGQEAWITVLILGVYALVVALAVVWIACRFPDRDPLKAIRCTLGSWATYPIVLLYCAFNVLIYAMSLSDVQTFTK
ILLLPDTPAWVLAVMIALFTIYTVLQGVEPIARTAYGVLVPLVLVILVLPFGVGKEIRLLQIDPFLWKGFSGVLRGAWLA
LPWAGQSLIVLSLMRHLSLRVNPYKWTLIGVGSAHLALAIMVLLISLVFGSILPSRLLYPGHELFAIVALTESIERIQAG
IMVLWLCGSLINITLHLYVAVEEGSLALGIQRRGWITLILGAAGVFLAQWAGGALYRRSIAREAWWIGMHIAGQLAVLAL
LGLATLLIRMRQGAGTSA

Sequences:

>Translated_338_residues
MLLESAGQEAWITVLILGVYALVVALAVVWIACRFPDRDPLKAIRCTLGSWATYPIVLLYCAFNVLIYAMSLSDVQTFTK
ILLLPDTPAWVLAVMIALFTIYTVLQGVEPIARTAYGVLVPLVLVILVLPFGVGKEIRLLQIDPFLWKGFSGVLRGAWLA
LPWAGQSLIVLSLMRHLSLRVNPYKWTLIGVGSAHLALAIMVLLISLVFGSILPSRLLYPGHELFAIVALTESIERIQAG
IMVLWLCGSLINITLHLYVAVEEGSLALGIQRRGWITLILGAAGVFLAQWAGGALYRRSIAREAWWIGMHIAGQLAVLAL
LGLATLLIRMRQGAGTSA
>Mature_338_residues
MLLESAGQEAWITVLILGVYALVVALAVVWIACRFPDRDPLKAIRCTLGSWATYPIVLLYCAFNVLIYAMSLSDVQTFTK
ILLLPDTPAWVLAVMIALFTIYTVLQGVEPIARTAYGVLVPLVLVILVLPFGVGKEIRLLQIDPFLWKGFSGVLRGAWLA
LPWAGQSLIVLSLMRHLSLRVNPYKWTLIGVGSAHLALAIMVLLISLVFGSILPSRLLYPGHELFAIVALTESIERIQAG
IMVLWLCGSLINITLHLYVAVEEGSLALGIQRRGWITLILGAAGVFLAQWAGGALYRRSIAREAWWIGMHIAGQLAVLAL
LGLATLLIRMRQGAGTSA

Specific function: May allow B.anthracis to germinate within phagocytic cells and therefore involved in virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004761 [H]

Pfam domain/function: PF03845 Spore_permease [H]

EC number: NA

Molecular weight: Translated: 36873; Mature: 36873

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLESAGQEAWITVLILGVYALVVALAVVWIACRFPDRDPLKAIRCTLGSWATYPIVLLY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
CAFNVLIYAMSLSDVQTFTKILLLPDTPAWVLAVMIALFTIYTVLQGVEPIARTAYGVLV
HHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
PLVLVILVLPFGVGKEIRLLQIDPFLWKGFSGVLRGAWLALPWAGQSLIVLSLMRHLSLR
HHHHHHHHHCCCCCCCEEEEEECHHHHHCHHHHHHHHHEEECCCCCHHHHHHHHHHHHEE
VNPYKWTLIGVGSAHLALAIMVLLISLVFGSILPSRLLYPGHELFAIVALTESIERIQAG
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IMVLWLCGSLINITLHLYVAVEEGSLALGIQRRGWITLILGAAGVFLAQWAGGALYRRSI
HHHHHHHHHHHEEEEEEEEEEECCCEEEEEECCCCEEEHHHHHHHHHHHHCCCHHHHHHH
AREAWWIGMHIAGQLAVLALLGLATLLIRMRQGAGTSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLLESAGQEAWITVLILGVYALVVALAVVWIACRFPDRDPLKAIRCTLGSWATYPIVLLY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
CAFNVLIYAMSLSDVQTFTKILLLPDTPAWVLAVMIALFTIYTVLQGVEPIARTAYGVLV
HHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
PLVLVILVLPFGVGKEIRLLQIDPFLWKGFSGVLRGAWLALPWAGQSLIVLSLMRHLSLR
HHHHHHHHHCCCCCCCEEEEEECHHHHHCHHHHHHHHHEEECCCCCHHHHHHHHHHHHEE
VNPYKWTLIGVGSAHLALAIMVLLISLVFGSILPSRLLYPGHELFAIVALTESIERIQAG
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IMVLWLCGSLINITLHLYVAVEEGSLALGIQRRGWITLILGAAGVFLAQWAGGALYRRSI
HHHHHHHHHHHEEEEEEEEEEECCCEEEEEECCCCEEEHHHHHHHHHHHHCCCHHHHHHH
AREAWWIGMHIAGQLAVLALLGLATLLIRMRQGAGTSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10411756; 10515943; 12004073; 12067380 [H]