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The map label for this gene is rnhB2

Identifier: 51893167

GI number: 51893167

Start: 2171084

End: 2171719

Strand: Reverse

Name: rnhB2

Synonym: STH2029

Alternate gene names: 51893167

Gene position: 2171719-2171084 (Counterclockwise)

Preceding gene: 51893168

Following gene: 51893166

Centisome position: 60.9

GC content: 72.33

Gene sequence:

>636_bases
ATGGCGGACCTGCGTCTGGAACGGGTGCTCTGGCGACATGGCTGCCAGGTGATCGGCGTGGATGAGGCCGGGCGCGGCCC
GCTGGCCGGGCCCGTGGTCGCCGCGGCCTGCATCCTGCCCCCGGACGCGGCGCTGCCCGGGGTGGACGACTCCAAGCGGA
TGACCGAGAAACGGCGGGAGGCGGCCTTCGCCGCGATCCAGGCGGTTGCGGTGGGCTGGGGGATCGGTATCGTGGACGCG
GCCCGCATCGATGAGATCAACATCCTCCAGGCGACCTTCGAGGCGATGGCCCAGGCGGTGGAAGGGGCCCGGGCCATGGC
GGCGGCGCGGCCGGGGCGCACGGCGGAGGCCGCACTCCTGGTGGACGGCAACCGGCCCCTGCCCCTGTGGCCCGGCTGGC
AGCGGACGGTGGTGGGCGGGGATCACAAGTCGCTTTCCATCGCCGCCGCGTCGATCCTGGCCAAGGTGACCCGTGACCGC
ATGATGATCGAGTACGACGCGCACTACCCGGAGTACGGCTTTGCCCGCAACAAGGGCTACGGCTCCCGGGAGCACTGGGA
CGCCCTGGAGCGGTACGGGCCGTGCCCGCTGCACCGGCGGACCTTCATCGGCCCGCGGCAGATCCGGTTCTTCTGA

Upstream 100 bases:

>100_bases
TTCCTCGGCCCCGTGATTCCCATCACCGGGGACGGCCGGGCCACCCACGACGAGCCGTGACGGGGCGGCGTAAGGACGCG
CACGGAGGAGGCAGGGCGAA

Downstream 100 bases:

>100_bases
TTCGGAGGGGTGGCCATGCCGTACGAGCTGCGCGACCTGGCGCCGGCTCTGGAGTACGCCGGACGCCATCCGGAGGCGGG
TTTTGCTCTGCTCCGGTCGC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII 2

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MADLRLERVLWRHGCQVIGVDEAGRGPLAGPVVAAACILPPDAALPGVDDSKRMTEKRREAAFAAIQAVAVGWGIGIVDA
ARIDEINILQATFEAMAQAVEGARAMAAARPGRTAEAALLVDGNRPLPLWPGWQRTVVGGDHKSLSIAAASILAKVTRDR
MMIEYDAHYPEYGFARNKGYGSREHWDALERYGPCPLHRRTFIGPRQIRFF

Sequences:

>Translated_211_residues
MADLRLERVLWRHGCQVIGVDEAGRGPLAGPVVAAACILPPDAALPGVDDSKRMTEKRREAAFAAIQAVAVGWGIGIVDA
ARIDEINILQATFEAMAQAVEGARAMAAARPGRTAEAALLVDGNRPLPLWPGWQRTVVGGDHKSLSIAAASILAKVTRDR
MMIEYDAHYPEYGFARNKGYGSREHWDALERYGPCPLHRRTFIGPRQIRFF
>Mature_210_residues
ADLRLERVLWRHGCQVIGVDEAGRGPLAGPVVAAACILPPDAALPGVDDSKRMTEKRREAAFAAIQAVAVGWGIGIVDAA
RIDEINILQATFEAMAQAVEGARAMAAARPGRTAEAALLVDGNRPLPLWPGWQRTVVGGDHKSLSIAAASILAKVTRDRM
MIEYDAHYPEYGFARNKGYGSREHWDALERYGPCPLHRRTFIGPRQIRFF

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=196, Percent_Identity=44.8979591836735, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH22_SYMTH (Q67MS9)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_075858.1
- ProteinModelPortal:   Q67MS9
- SMR:   Q67MS9
- GeneID:   2980709
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH2029
- NMPDR:   fig|292459.1.peg.1958
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- BioCyc:   STHE292459:STH2029-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 23039; Mature: 22908

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLRLERVLWRHGCQVIGVDEAGRGPLAGPVVAAACILPPDAALPGVDDSKRMTEKRRE
CCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AAFAAIQAVAVGWGIGIVDAARIDEINILQATFEAMAQAVEGARAMAAARPGRTAEAALL
HHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VDGNRPLPLWPGWQRTVVGGDHKSLSIAAASILAKVTRDRMMIEYDAHYPEYGFARNKGY
EECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCC
GSREHWDALERYGPCPLHRRTFIGPRQIRFF
CCHHHHHHHHHCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
ADLRLERVLWRHGCQVIGVDEAGRGPLAGPVVAAACILPPDAALPGVDDSKRMTEKRRE
CCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AAFAAIQAVAVGWGIGIVDAARIDEINILQATFEAMAQAVEGARAMAAARPGRTAEAALL
HHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VDGNRPLPLWPGWQRTVVGGDHKSLSIAAASILAKVTRDRMMIEYDAHYPEYGFARNKGY
EECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCC
GSREHWDALERYGPCPLHRRTFIGPRQIRFF
CCHHHHHHHHHCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA