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The map label for this gene is xseA [H]

Identifier: 51892984

GI number: 51892984

Start: 1991135

End: 1992382

Strand: Reverse

Name: xseA [H]

Synonym: STH1846

Alternate gene names: 51892984

Gene position: 1992382-1991135 (Counterclockwise)

Preceding gene: 51892985

Following gene: 51892983

Centisome position: 55.87

GC content: 72.12

Gene sequence:

>1248_bases
TTGGAGTCCTTCGCTCTGGCGGAGAGCGGGCGTCAACTCCTGACGGTGAGGGAGCTGACCCGCTACGTGAAGGACCTTCT
GGACGAGGACCCGCTGCTCCGGTCGGTCTGGGTTCAGGGAGAGATCTCCAACTTCAAGTGGCACCACTCGGGCCACATCT
ACTTCACCCTGAAGGACGAGGTCGCCCAGGTGAAGGTCGTCATGTTCCGCTCGTACGCCAACCGGCTGCGTTTCCGGCCC
GAGAACGGCATGCAGGTGATCGTGCAGGGGAACGTGACGGTGTTCGAACGGGACGGCGTGTATCAGCTCTACGCCGCCGC
GATGGAGCCCTACGGCCTCGGCGCGCTGCACCTGGAGTTCGAGCAGCTGAAGCGCCGGCTCGCCGCGGAGGGGCTGTTCG
ACGAGGCGCTGAAGCGGCCGATTCCGAGCCTGCCCCGGGCGGTGGGGCTGGTGACCGCCCCCACCGGGGCGGCCATCCGG
GACATGATCACCGTCGCCCGCCGCCGGTTCCCCGGCATGCGGCTGGTGCTGGCCCCCGCCCTGGTACAGGGGCCGGATGC
GCCGGAGAGCCTGATCCGGGCGCTGGGCCTGGTTGCCCGGGTGCCCGAGGTGGACGTGGTGATCATCGGCCGGGGCGGCG
GGTCGTTGGAGGACCTGTGGGCGTTCAACGACGAGCGGCTGGCCCGGGCGATCCGGGCGTGCCCGGTGCCCGTGGTTTCG
GCGGTGGGCCACGAGACCGACTACACCATCGCCGACTTCGCCGCGGACCTGCGGGCTCCCACGCCGTCCGCCGCGGCTGA
GCTGGTGGTGCCCTCCCGTTCCGAGCTGCTGGGCGTGGTGGACGGGCTGCGGATCCGTCTGTCCACCGCCGCCCGCCGGT
CGGTGGAGCGGCGGCGCATCCGGCTCCGGGCCCTCACCGAGCGGCCGGTGCTGCAGCGGCCGCAGGGCCGGGTCCTGCAG
GACCGGCAGCGGCTGGATGGCCTGGTCCGGCGGCTGGAGTACCTGGGCGGCAGCCTGCTGGCCGCCCGGCGGCGGGAGCT
GGGCGGTCTGGCCGGCCGCCTGGAGGCGCTGTCGCCGCTGGCGGTGCTGGCGCGCGGCTACGCGATCGCCCGCACCGAGG
AGGGGCGCGTGGTGAAGGACGCGGCTCAGCTTCAGGTGGGCGACCGGCTGGACGTGCTCCTCCATAGAGGATCTGTGCGC
TGTCAGGTGGAAGAGATACGCGGCGACGCGGGGGAGGGGACGAGATGA

Upstream 100 bases:

>100_bases
AAGGCGGCCAGAATGCAGACCGGCCGGTAGGCTGCGCCCCGCCGGACGGCCTCACGGGTGCGCGAGGCAGCCCCTTCCGG
GCGCATGAGGAGGCGATGCT

Downstream 100 bases:

>100_bases
CGCAGGAGCTCAGCTTCGAGGAGGCCATTCAGCGGCTGGAGCAGGTGGTCAGGGAGCTGGAGAGCGGCGATCTGCCGCTG
GAGCGTGGCCTGGAGCTCTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MESFALAESGRQLLTVRELTRYVKDLLDEDPLLRSVWVQGEISNFKWHHSGHIYFTLKDEVAQVKVVMFRSYANRLRFRP
ENGMQVIVQGNVTVFERDGVYQLYAAAMEPYGLGALHLEFEQLKRRLAAEGLFDEALKRPIPSLPRAVGLVTAPTGAAIR
DMITVARRRFPGMRLVLAPALVQGPDAPESLIRALGLVARVPEVDVVIIGRGGGSLEDLWAFNDERLARAIRACPVPVVS
AVGHETDYTIADFAADLRAPTPSAAAELVVPSRSELLGVVDGLRIRLSTAARRSVERRRIRLRALTERPVLQRPQGRVLQ
DRQRLDGLVRRLEYLGGSLLAARRRELGGLAGRLEALSPLAVLARGYAIARTEEGRVVKDAAQLQVGDRLDVLLHRGSVR
CQVEEIRGDAGEGTR

Sequences:

>Translated_415_residues
MESFALAESGRQLLTVRELTRYVKDLLDEDPLLRSVWVQGEISNFKWHHSGHIYFTLKDEVAQVKVVMFRSYANRLRFRP
ENGMQVIVQGNVTVFERDGVYQLYAAAMEPYGLGALHLEFEQLKRRLAAEGLFDEALKRPIPSLPRAVGLVTAPTGAAIR
DMITVARRRFPGMRLVLAPALVQGPDAPESLIRALGLVARVPEVDVVIIGRGGGSLEDLWAFNDERLARAIRACPVPVVS
AVGHETDYTIADFAADLRAPTPSAAAELVVPSRSELLGVVDGLRIRLSTAARRSVERRRIRLRALTERPVLQRPQGRVLQ
DRQRLDGLVRRLEYLGGSLLAARRRELGGLAGRLEALSPLAVLARGYAIARTEEGRVVKDAAQLQVGDRLDVLLHRGSVR
CQVEEIRGDAGEGTR
>Mature_415_residues
MESFALAESGRQLLTVRELTRYVKDLLDEDPLLRSVWVQGEISNFKWHHSGHIYFTLKDEVAQVKVVMFRSYANRLRFRP
ENGMQVIVQGNVTVFERDGVYQLYAAAMEPYGLGALHLEFEQLKRRLAAEGLFDEALKRPIPSLPRAVGLVTAPTGAAIR
DMITVARRRFPGMRLVLAPALVQGPDAPESLIRALGLVARVPEVDVVIIGRGGGSLEDLWAFNDERLARAIRACPVPVVS
AVGHETDYTIADFAADLRAPTPSAAAELVVPSRSELLGVVDGLRIRLSTAARRSVERRRIRLRALTERPVLQRPQGRVLQ
DRQRLDGLVRRLEYLGGSLLAARRRELGGLAGRLEALSPLAVLARGYAIARTEEGRVVKDAAQLQVGDRLDVLLHRGSVR
CQVEEIRGDAGEGTR

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=440, Percent_Identity=42.7272727272727, Blast_Score=337, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45943; Mature: 45943

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESFALAESGRQLLTVRELTRYVKDLLDEDPLLRSVWVQGEISNFKWHHSGHIYFTLKDE
CCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCEEEEECCEEEEEECCC
VAQVKVVMFRSYANRLRFRPENGMQVIVQGNVTVFERDGVYQLYAAAMEPYGLGALHLEF
HHHHHHHHHHHHHHHHEECCCCCCEEEEECCEEEEECCCHHHHHHHHHCCCCCCEEEEEH
EQLKRRLAAEGLFDEALKRPIPSLPRAVGLVTAPTGAAIRDMITVARRRFPGMRLVLAPA
HHHHHHHHHCCHHHHHHHCCCCCCCHHHCEEECCCCHHHHHHHHHHHHHCCCCEEEECHH
LVQGPDAPESLIRALGLVARVPEVDVVIIGRGGGSLEDLWAFNDERLARAIRACPVPVVS
HHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHH
AVGHETDYTIADFAADLRAPTPSAAAELVVPSRSELLGVVDGLRIRLSTAARRSVERRRI
HCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHCCCEEEEHHHHHHHHHHHHH
RLRALTERPVLQRPQGRVLQDRQRLDGLVRRLEYLGGSLLAARRRELGGLAGRLEALSPL
HHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHH
AVLARGYAIARTEEGRVVKDAAQLQVGDRLDVLLHRGSVRCQVEEIRGDAGEGTR
HHHHCCCEEEECCCCCEEHHHHHHCCCCCHHHHEECCCCEEEHHHHCCCCCCCCC
>Mature Secondary Structure
MESFALAESGRQLLTVRELTRYVKDLLDEDPLLRSVWVQGEISNFKWHHSGHIYFTLKDE
CCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCEEEEECCEEEEEECCC
VAQVKVVMFRSYANRLRFRPENGMQVIVQGNVTVFERDGVYQLYAAAMEPYGLGALHLEF
HHHHHHHHHHHHHHHHEECCCCCCEEEEECCEEEEECCCHHHHHHHHHCCCCCCEEEEEH
EQLKRRLAAEGLFDEALKRPIPSLPRAVGLVTAPTGAAIRDMITVARRRFPGMRLVLAPA
HHHHHHHHHCCHHHHHHHCCCCCCCHHHCEEECCCCHHHHHHHHHHHHHCCCCEEEECHH
LVQGPDAPESLIRALGLVARVPEVDVVIIGRGGGSLEDLWAFNDERLARAIRACPVPVVS
HHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHH
AVGHETDYTIADFAADLRAPTPSAAAELVVPSRSELLGVVDGLRIRLSTAARRSVERRRI
HCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHCCCEEEEHHHHHHHHHHHHH
RLRALTERPVLQRPQGRVLQDRQRLDGLVRRLEYLGGSLLAARRRELGGLAGRLEALSPL
HHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHH
AVLARGYAIARTEEGRVVKDAAQLQVGDRLDVLLHRGSVRCQVEEIRGDAGEGTR
HHHHCCCEEEECCCCCEEHHHHHHCCCCCHHHHEECCCCEEEHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA