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The map label for this gene is hfq

Identifier: 51892884

GI number: 51892884

Start: 1892190

End: 1892462

Strand: Reverse

Name: hfq

Synonym: STH1746

Alternate gene names: 51892884

Gene position: 1892462-1892190 (Counterclockwise)

Preceding gene: 51892885

Following gene: 51892882

Centisome position: 53.07

GC content: 63.74

Gene sequence:

>273_bases
GTGACCAAGGCGTCAGCCAGCCTGCAGGACGGGTTCCTCAACCTGCTGCGCAGGGAGAACATCCCGGCCACCATCTATCT
GGTGAACGGATACCAGCTGAAAGGGTACATTCGGGGATTCGACAACTTCACCGTGGCGGTGGAGGTCGACGGGAGGGTGC
AGCTCGTCTACAAGCACGCCCTGTCGACGATCACGCCAGCCCGGCCGCTGCCGGTCTCCGTTTCGCAGATCATGCGGGCC
GGGGAGGGGCAGGAAGTGGAAGGCGAGGAGTAG

Upstream 100 bases:

>100_bases
TGGATCTCACCGGGCCGGAGGCCCGCAACCGGGCGACGGAGGAGATCGTCAGACTGATCAGGGAGAAATGGCCCTGTAGA
GAGAGGAAGGGGCGGATCGA

Downstream 100 bases:

>100_bases
CAAACGGGGACCGCTGGGCGGGCGGTCCCCTCTGCTTTTCGGTTCGCTCCGGTGCGGCCGGGTGCATCAGGGGCCCCCTT
ACGGCCCGACCCCGGCCATG

Product: host factor-1 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 89

Protein sequence:

>90_residues
MTKASASLQDGFLNLLRRENIPATIYLVNGYQLKGYIRGFDNFTVAVEVDGRVQLVYKHALSTITPARPLPVSVSQIMRA
GEGQEVEGEE

Sequences:

>Translated_90_residues
MTKASASLQDGFLNLLRRENIPATIYLVNGYQLKGYIRGFDNFTVAVEVDGRVQLVYKHALSTITPARPLPVSVSQIMRA
GEGQEVEGEE
>Mature_89_residues
TKASASLQDGFLNLLRRENIPATIYLVNGYQLKGYIRGFDNFTVAVEVDGRVQLVYKHALSTITPARPLPVSVSQIMRAG
EGQEVEGEE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=64, Percent_Identity=54.6875, Blast_Score=78, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_SYMTH (Q67NL2)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_075575.1
- ProteinModelPortal:   Q67NL2
- SMR:   Q67NL2
- GeneID:   2979707
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH1746
- NMPDR:   fig|292459.1.peg.1684
- HOGENOM:   HBG645207
- OMA:   KNTINIQ
- BioCyc:   STHE292459:STH1746-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9939; Mature: 9808

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKASASLQDGFLNLLRRENIPATIYLVNGYQLKGYIRGFDNFTVAVEVDGRVQLVYKHA
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCEEEEEEECCEEEEEEEHH
LSTITPARPLPVSVSQIMRAGEGQEVEGEE
HHHCCCCCCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TKASASLQDGFLNLLRRENIPATIYLVNGYQLKGYIRGFDNFTVAVEVDGRVQLVYKHA
CCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCEEEEEEECCEEEEEEEHH
LSTITPARPLPVSVSQIMRAGEGQEVEGEE
HHHCCCCCCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA