| Definition | Symbiobacterium thermophilum IAM 14863 chromosome, complete genome. |
|---|---|
| Accession | NC_006177 |
| Length | 3,566,135 |
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The map label for this gene is pcrA [H]
Identifier: 51892441
GI number: 51892441
Start: 1438983
End: 1441064
Strand: Reverse
Name: pcrA [H]
Synonym: STH1303
Alternate gene names: 51892441
Gene position: 1441064-1438983 (Counterclockwise)
Preceding gene: 51892442
Following gene: 51892440
Centisome position: 40.41
GC content: 68.54
Gene sequence:
>2082_bases ATGGCGCTTGCCAGGGACATGAACATCAAGCCCTCGTGCTTGGCCGAGCTACGCGCGCTGCCCGCGCACATGGCCAGCCA GGTATGGGAGAAGATCGACTTCCTGTGCCAGGATCCGCTGCCGGACGGCCACAGCAAGAAGAAGCTCGGAAAGTGGCCCG ACGTGTATCGGCTCCGCATCGGCGACTACCGGCTGTTCTATAGCTTCGGCACCACCTGGATTCGGCTGCTCGGCATCCGG CACCGCCGTGAGGCCTACAGGCGGGATGTGGCGTACGAGGAGCCGACGTTCATGCCGGAGACGATCGAAGATCCTGACCT GGACGAGCTGTTGTTCCAGGGTGCGGGGAGCCGCCCCGCCTGGACGCCTGGGCAGGAGGCCACTCCACGGGAGTTGCCGC GGCCCATCACCGCCGAGTGGCTGGACTCCCTGGGCGTGCCGCCGGAGGCCCAGCCGGCGCTCCTGGCCTGCCGGACAGAG GACGACCTGCTAAACGCGGAGGTGGACCCACGTTACATCGAGCGGGTGGTCGAGAACCTGTTCCCGCGCCCCATCGACGA GGTCATGCAGCAGCCCGACCTGGCCGTCTTCAGCACGAAGGACCTGGACCGGTACCACAAGGACGACCTCATCGGGTTCC TGCTCCGGCTCGACCCCTCGCAGGAGCGTCTGGTGGACTGGGCCCTGGAGGGCCCGGTGCTCATCAAGGGGGGGCCGGGC ACGGGCAAGTCAACGGTGGCACTTTACCGGGTGCAGCGGCTCATCGAGCACAGACTGAAAACCGGCCGACAGACGCCCCG AATCCTCTTCACCACCTACACCCCTGCCCTGGCGCGGTTCTCGGAGCAGCTACTGGAGAGCCTGCTGGGCGAGAACCGCA ACCTAGTGACAGTGCGGACGTCCGACGGCGTGGCCGAGGACATCGTATCCCGGCTGGAGCCGGTGCGGGTGGTAACCGAC CGCCAGGACCTGGAGGCCCGGATCGCGCGCCTCATGGATCGGCATCAGGACCACCTGCCCGAGTCGGTCCGCCGGCTGCG GCCGGACTATGTGCTGGATGAGATAGAGTGGATCATCGACGGACGCAACCTCAAGAGTCTGGACGAGTACCTGGCCGCCA GCCGGACGGGCCGAGGCATCGCCCTGGGCGAGGCAGCCCGTCGAGCCGTGTGGGAGCTCTACACCGCTTTCTGCACGGAA CTGGAGCGGGACGGACTGTGTTCCCCGTCCCGGCTGAGGGTCCGGGCCCTGGAGCATGTGCGGGCCGGCCGCGGCGGCCA GCGCTATGACGCGGTGGTCATCGACGAGGCGCAGGACCTCACCCCCGCCATGCTCTCCCTGCTGGTGGAACTGGCGGAGT CCGAGCGAGGGATCTACGTTACCGCCGACCCGTCCCAGTCCATCTACTTCCGCGGGTTCAGCTGGCAGCTGGTCCACCAG CGGCTACGTTTCCGCGGCCGGGCCAAGCTGCTCCGGCGCAACTACCGCTCTACACGGGAGATCGCCGAGGTCGCCCGCGC CTTCCTGGAGAAGAGCGGGGCGGGTGACCCGGAGTCGCTGCAGACCGACTCGCCCGTGACGGGGCCGGCGCCCGTACTGG CCACGTACGAGAGCGAAGCCGAGCAGTGGGAGCAGGCGGCCGACTTCATTCGGCAGATGACCCGGTACGTGCGCATGAAC CATGGGGCCGCCGCGGTGCTGGTCCCCTCCTCCTCCGTGGGTCAGCAGGCCGAGGAAGGGCTCACCCGGGCCGGGCTGAA GGCCCGGTTCATGCGCGGCTCCCAGCTCGACCTGAAGACAGACGCGGTGAAGGTGCTGACGCTGCAGGCGGCCAAAGGAC TGGAGTTCCCCGTGGTGGTGATCGCCGGGCTGTCGGCCCGGTACTTCCCCCGCCTGCCCGCCGACATGGACCCGGAGGAG CGGGACGAGGAGATGCAGACCGCCCGCCGCACGCTGTACGTGGGGATGACCCGGGCCATGCGTTGCCTGGTGATCCTGCA CCCGCGTCGGGCTCCTTCCCCCCTCATCGCCGAGCTGGAGGGACCCCACTGGACACTGGCGGGGCAGCAGGCGGAGGGAT GA
Upstream 100 bases:
>100_bases CATTCAGGGGCAGGTCGCCCATGAGATCGACCGCCACTTCGCCGCGCTAGTCCGTGACGCTGTGCTTGTGGAATACGATC GCAGCCAGGAGGAGTAAGGC
Downstream 100 bases:
>100_bases TCCGTGGACTGGGAAGGGCTAAGCCGAGCGCTGGCGGCGCGGTATGGCAGTCCCCGGCACGGCAACCCCACCGACCCGAC CGACTGCCTGTTCTACCTGA
Product: putative DNA helicase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 693; Mature: 692
Protein sequence:
>693_residues MALARDMNIKPSCLAELRALPAHMASQVWEKIDFLCQDPLPDGHSKKKLGKWPDVYRLRIGDYRLFYSFGTTWIRLLGIR HRREAYRRDVAYEEPTFMPETIEDPDLDELLFQGAGSRPAWTPGQEATPRELPRPITAEWLDSLGVPPEAQPALLACRTE DDLLNAEVDPRYIERVVENLFPRPIDEVMQQPDLAVFSTKDLDRYHKDDLIGFLLRLDPSQERLVDWALEGPVLIKGGPG TGKSTVALYRVQRLIEHRLKTGRQTPRILFTTYTPALARFSEQLLESLLGENRNLVTVRTSDGVAEDIVSRLEPVRVVTD RQDLEARIARLMDRHQDHLPESVRRLRPDYVLDEIEWIIDGRNLKSLDEYLAASRTGRGIALGEAARRAVWELYTAFCTE LERDGLCSPSRLRVRALEHVRAGRGGQRYDAVVIDEAQDLTPAMLSLLVELAESERGIYVTADPSQSIYFRGFSWQLVHQ RLRFRGRAKLLRRNYRSTREIAEVARAFLEKSGAGDPESLQTDSPVTGPAPVLATYESEAEQWEQAADFIRQMTRYVRMN HGAAAVLVPSSSVGQQAEEGLTRAGLKARFMRGSQLDLKTDAVKVLTLQAAKGLEFPVVVIAGLSARYFPRLPADMDPEE RDEEMQTARRTLYVGMTRAMRCLVILHPRRAPSPLIAELEGPHWTLAGQQAEG
Sequences:
>Translated_693_residues MALARDMNIKPSCLAELRALPAHMASQVWEKIDFLCQDPLPDGHSKKKLGKWPDVYRLRIGDYRLFYSFGTTWIRLLGIR HRREAYRRDVAYEEPTFMPETIEDPDLDELLFQGAGSRPAWTPGQEATPRELPRPITAEWLDSLGVPPEAQPALLACRTE DDLLNAEVDPRYIERVVENLFPRPIDEVMQQPDLAVFSTKDLDRYHKDDLIGFLLRLDPSQERLVDWALEGPVLIKGGPG TGKSTVALYRVQRLIEHRLKTGRQTPRILFTTYTPALARFSEQLLESLLGENRNLVTVRTSDGVAEDIVSRLEPVRVVTD RQDLEARIARLMDRHQDHLPESVRRLRPDYVLDEIEWIIDGRNLKSLDEYLAASRTGRGIALGEAARRAVWELYTAFCTE LERDGLCSPSRLRVRALEHVRAGRGGQRYDAVVIDEAQDLTPAMLSLLVELAESERGIYVTADPSQSIYFRGFSWQLVHQ RLRFRGRAKLLRRNYRSTREIAEVARAFLEKSGAGDPESLQTDSPVTGPAPVLATYESEAEQWEQAADFIRQMTRYVRMN HGAAAVLVPSSSVGQQAEEGLTRAGLKARFMRGSQLDLKTDAVKVLTLQAAKGLEFPVVVIAGLSARYFPRLPADMDPEE RDEEMQTARRTLYVGMTRAMRCLVILHPRRAPSPLIAELEGPHWTLAGQQAEG >Mature_692_residues ALARDMNIKPSCLAELRALPAHMASQVWEKIDFLCQDPLPDGHSKKKLGKWPDVYRLRIGDYRLFYSFGTTWIRLLGIRH RREAYRRDVAYEEPTFMPETIEDPDLDELLFQGAGSRPAWTPGQEATPRELPRPITAEWLDSLGVPPEAQPALLACRTED DLLNAEVDPRYIERVVENLFPRPIDEVMQQPDLAVFSTKDLDRYHKDDLIGFLLRLDPSQERLVDWALEGPVLIKGGPGT GKSTVALYRVQRLIEHRLKTGRQTPRILFTTYTPALARFSEQLLESLLGENRNLVTVRTSDGVAEDIVSRLEPVRVVTDR QDLEARIARLMDRHQDHLPESVRRLRPDYVLDEIEWIIDGRNLKSLDEYLAASRTGRGIALGEAARRAVWELYTAFCTEL ERDGLCSPSRLRVRALEHVRAGRGGQRYDAVVIDEAQDLTPAMLSLLVELAESERGIYVTADPSQSIYFRGFSWQLVHQR LRFRGRAKLLRRNYRSTREIAEVARAFLEKSGAGDPESLQTDSPVTGPAPVLATYESEAEQWEQAADFIRQMTRYVRMNH GAAAVLVPSSSVGQQAEEGLTRAGLKARFMRGSQLDLKTDAVKVLTLQAAKGLEFPVVVIAGLSARYFPRLPADMDPEER DEEMQTARRTLYVGMTRAMRCLVILHPRRAPSPLIAELEGPHWTLAGQQAEG
Specific function: Essential helicase [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
None
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005751 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 78514; Mature: 78382
Theoretical pI: Translated: 6.28; Mature: 6.28
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALARDMNIKPSCLAELRALPAHMASQVWEKIDFLCQDPLPDGHSKKKLGKWPDVYRLRI CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEEE GDYRLFYSFGTTWIRLLGIRHRREAYRRDVAYEEPTFMPETIEDPDLDELLFQGAGSRPA CCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC WTPGQEATPRELPRPITAEWLDSLGVPPEAQPALLACRTEDDLLNAEVDPRYIERVVENL CCCCCCCCHHHCCCCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHH FPRPIDEVMQQPDLAVFSTKDLDRYHKDDLIGFLLRLDPSQERLVDWALEGPVLIKGGPG CCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCC TGKSTVALYRVQRLIEHRLKTGRQTPRILFTTYTPALARFSEQLLESLLGENRNLVTVRT CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEC SDGVAEDIVSRLEPVRVVTDRQDLEARIARLMDRHQDHLPESVRRLRPDYVLDEIEWIID CCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCC GRNLKSLDEYLAASRTGRGIALGEAARRAVWELYTAFCTELERDGLCSPSRLRVRALEHV CCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH RAGRGGQRYDAVVIDEAQDLTPAMLSLLVELAESERGIYVTADPSQSIYFRGFSWQLVHQ HCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCHHHHHHH RLRFRGRAKLLRRNYRSTREIAEVARAFLEKSGAGDPESLQTDSPVTGPAPVLATYESEA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHH EQWEQAADFIRQMTRYVRMNHGAAAVLVPSSSVGQQAEEGLTRAGLKARFMRGSQLDLKT HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCHHHHHHCCCCCCCCH DAVKVLTLQAAKGLEFPVVVIAGLSARYFPRLPADMDPEERDEEMQTARRTLYVGMTRAM HHHHEEEEHHHCCCCCCCCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH RCLVILHPRRAPSPLIAELEGPHWTLAGQQAEG HEHHEECCCCCCCCHHEECCCCEEEECCCCCCC >Mature Secondary Structure ALARDMNIKPSCLAELRALPAHMASQVWEKIDFLCQDPLPDGHSKKKLGKWPDVYRLRI CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEEE GDYRLFYSFGTTWIRLLGIRHRREAYRRDVAYEEPTFMPETIEDPDLDELLFQGAGSRPA CCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC WTPGQEATPRELPRPITAEWLDSLGVPPEAQPALLACRTEDDLLNAEVDPRYIERVVENL CCCCCCCCHHHCCCCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHH FPRPIDEVMQQPDLAVFSTKDLDRYHKDDLIGFLLRLDPSQERLVDWALEGPVLIKGGPG CCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCC TGKSTVALYRVQRLIEHRLKTGRQTPRILFTTYTPALARFSEQLLESLLGENRNLVTVRT CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEC SDGVAEDIVSRLEPVRVVTDRQDLEARIARLMDRHQDHLPESVRRLRPDYVLDEIEWIID CCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCC GRNLKSLDEYLAASRTGRGIALGEAARRAVWELYTAFCTELERDGLCSPSRLRVRALEHV CCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH RAGRGGQRYDAVVIDEAQDLTPAMLSLLVELAESERGIYVTADPSQSIYFRGFSWQLVHQ HCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCHHHHHHH RLRFRGRAKLLRRNYRSTREIAEVARAFLEKSGAGDPESLQTDSPVTGPAPVLATYESEA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHH EQWEQAADFIRQMTRYVRMNHGAAAVLVPSSSVGQQAEEGLTRAGLKARFMRGSQLDLKT HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCHHHHHHCCCCCCCCH DAVKVLTLQAAKGLEFPVVVIAGLSARYFPRLPADMDPEERDEEMQTARRTLYVGMTRAM HHHHEEEEHHHCCCCCCCCEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH RCLVILHPRRAPSPLIAELEGPHWTLAGQQAEG HEHHEECCCCCCCCHHEECCCCEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA