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The map label for this gene is mpg1 [H]

Identifier: 51892258

GI number: 51892258

Start: 1247181

End: 1248212

Strand: Reverse

Name: mpg1 [H]

Synonym: STH1120

Alternate gene names: 51892258

Gene position: 1248212-1247181 (Counterclockwise)

Preceding gene: 51892259

Following gene: 51892257

Centisome position: 35.0

GC content: 68.7

Gene sequence:

>1032_bases
ATGGCTGTTCGCGCAATCCTGTTGGCCGGAGGGCTGGGTACGCGGCTGCACCCCCTGACGGTTGAGCTGCCGAAGCCAAT
GGTGCCTGTACTCGGCAAACCCTGGCTGAGTCGGCTCATCGACCAGCTGGCCGCCTTCGGGGTCACCGACATCACCCTGA
GCCTCCGCCACGGCGGGCAGGTCGTCACGGACTACTTCAGGGAATCGCCCCCGGGCGTACGGCTGCGGTTCGCGGTTGAG
CCCCAGCCCCTTGGAACCGGTGGTGCCATCCGGTTCGCCGCCGGACCGGACCCCACGGACACCCTACTCATCCTGAACGC
GGATATTGTACAGACATTTGATCTGAATGCCCTGTTAGAGTTCCATCGCCAGCACCGTGCCCAGGTGACCATCGGGTTGG
TCGAGGTGGCCGATCCGTCCGCCTACGGCGCTGTAGAACTGGATAAGAACAGTCGTGTTACGCGATTTGTGGAAAAGCCA
CGCCCGGGTGAGACGGACAGCCGGATGGTCAACGCCGGTGTGTACGTGTTCGACCCGGGCGTTCTGTCTTGGATCCCGCC
GGAGCGACCCGTCTCGGTGGAGCGGGAGACCTTCCCGGCCCTGCTCCGGGACGGCGTGCGAGTCTACGGCTGCCTCTGCA
CCGGGTACTGGAAGGACATCGGCACCGGCGACCGCTACCTCCAACTGCACCGGGACATCCTGGAGGGGCGTTGCCCCATC
CCGGTCTCCGGCCCCGTGCGCGGCCCGGCCCACTGGCAGGCGGACGACGCGGACGTCTCCCCGGACGCCCGGATCATGCC
GCCGGTCTACATCGGGTCCGGCGCGGTGATCGAGGCCGGCGCGCAGGTCGGCCCCCGGGCGGTGATCGGCGCGGGCTGCC
TGGTGGCCAAGGGCGCCCGCATCAGCGACTCGGTGCTGTGGGACGGGGCGCGGGTTGGCGCCGGCGCCACCGTGCGCCAC
TCTGTCATCGGCTTCGCGACGGGGATCGGCGGCGGCACCGTCGAGAACGTGCTGCTGGCCGGCTGGAGGTGA

Upstream 100 bases:

>100_bases
CGGGAGGTTGCTGCCCGCACCGAAATGCGGTACAATATGGAACCGTTAGCACTCACCTATGACGAGTGCTAGTAGTATCT
CGGGCCGAGGAGGGATCTTC

Downstream 100 bases:

>100_bases
GGGGCGGTGAGTGCGAGGCTTGCGATCGTCAGCACGTACCCGCCCCGGCAGTGCGGCCTGGCGACGTTCTCTGCGCACCT
GCGCGGGGGCCTTCTGGCCG

Product: putative mannose-1-phosphate guanyltransferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MAVRAILLAGGLGTRLHPLTVELPKPMVPVLGKPWLSRLIDQLAAFGVTDITLSLRHGGQVVTDYFRESPPGVRLRFAVE
PQPLGTGGAIRFAAGPDPTDTLLILNADIVQTFDLNALLEFHRQHRAQVTIGLVEVADPSAYGAVELDKNSRVTRFVEKP
RPGETDSRMVNAGVYVFDPGVLSWIPPERPVSVERETFPALLRDGVRVYGCLCTGYWKDIGTGDRYLQLHRDILEGRCPI
PVSGPVRGPAHWQADDADVSPDARIMPPVYIGSGAVIEAGAQVGPRAVIGAGCLVAKGARISDSVLWDGARVGAGATVRH
SVIGFATGIGGGTVENVLLAGWR

Sequences:

>Translated_343_residues
MAVRAILLAGGLGTRLHPLTVELPKPMVPVLGKPWLSRLIDQLAAFGVTDITLSLRHGGQVVTDYFRESPPGVRLRFAVE
PQPLGTGGAIRFAAGPDPTDTLLILNADIVQTFDLNALLEFHRQHRAQVTIGLVEVADPSAYGAVELDKNSRVTRFVEKP
RPGETDSRMVNAGVYVFDPGVLSWIPPERPVSVERETFPALLRDGVRVYGCLCTGYWKDIGTGDRYLQLHRDILEGRCPI
PVSGPVRGPAHWQADDADVSPDARIMPPVYIGSGAVIEAGAQVGPRAVIGAGCLVAKGARISDSVLWDGARVGAGATVRH
SVIGFATGIGGGTVENVLLAGWR
>Mature_342_residues
AVRAILLAGGLGTRLHPLTVELPKPMVPVLGKPWLSRLIDQLAAFGVTDITLSLRHGGQVVTDYFRESPPGVRLRFAVEP
QPLGTGGAIRFAAGPDPTDTLLILNADIVQTFDLNALLEFHRQHRAQVTIGLVEVADPSAYGAVELDKNSRVTRFVEKPR
PGETDSRMVNAGVYVFDPGVLSWIPPERPVSVERETFPALLRDGVRVYGCLCTGYWKDIGTGDRYLQLHRDILEGRCPIP
VSGPVRGPAHWQADDADVSPDARIMPPVYIGSGAVIEAGAQVGPRAVIGAGCLVAKGARISDSVLWDGARVGAGATVRHS
VIGFATGIGGGTVENVLLAGWR

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=345, Percent_Identity=30.7246376811594, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI11761619, Length=333, Percent_Identity=30.6306306306306, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI31881779, Length=376, Percent_Identity=27.6595744680851, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI45447090, Length=376, Percent_Identity=27.6595744680851, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1788351, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790224, Length=239, Percent_Identity=26.7782426778243, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788355, Length=272, Percent_Identity=25.3676470588235, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=344, Percent_Identity=29.9418604651163, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17509979, Length=348, Percent_Identity=27.2988505747126, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17509981, Length=333, Percent_Identity=26.7267267267267, Blast_Score=97, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320148, Length=334, Percent_Identity=31.7365269461078, Blast_Score=168, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21355443, Length=331, Percent_Identity=30.2114803625378, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24644084, Length=331, Percent_Identity=30.2114803625378, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24653912, Length=379, Percent_Identity=25.8575197889182, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 36622; Mature: 36490

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRAILLAGGLGTRLHPLTVELPKPMVPVLGKPWLSRLIDQLAAFGVTDITLSLRHGGQ
CCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCH
VVTDYFRESPPGVRLRFAVEPQPLGTGGAIRFAAGPDPTDTLLILNADIVQTFDLNALLE
HHHHHHHCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECCHHHHCCHHHHHH
FHRQHRAQVTIGLVEVADPSAYGAVELDKNSRVTRFVEKPRPGETDSRMVNAGVYVFDPG
HHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCHHHHHCCCCCCCCCEEEECCEEEECCC
VLSWIPPERPVSVERETFPALLRDGVRVYGCLCTGYWKDIGTGDRYLQLHRDILEGRCPI
CEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHCCCCCC
PVSGPVRGPAHWQADDADVSPDARIMPPVYIGSGAVIEAGAQVGPRAVIGAGCLVAKGAR
CCCCCCCCCCCCCCCCCCCCCCCEECCCEEECCCCEEECCCCCCCCCEEECCHHEECCCC
ISDSVLWDGARVGAGATVRHSVIGFATGIGGGTVENVLLAGWR
CCCCEEECCCCCCCCCHHHHHHHHHEECCCCCCHHHHEEECCC
>Mature Secondary Structure 
AVRAILLAGGLGTRLHPLTVELPKPMVPVLGKPWLSRLIDQLAAFGVTDITLSLRHGGQ
CEEEEEEECCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCH
VVTDYFRESPPGVRLRFAVEPQPLGTGGAIRFAAGPDPTDTLLILNADIVQTFDLNALLE
HHHHHHHCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECCHHHHCCHHHHHH
FHRQHRAQVTIGLVEVADPSAYGAVELDKNSRVTRFVEKPRPGETDSRMVNAGVYVFDPG
HHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCHHHHHCCCCCCCCCEEEECCEEEECCC
VLSWIPPERPVSVERETFPALLRDGVRVYGCLCTGYWKDIGTGDRYLQLHRDILEGRCPI
CEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHCCCCCC
PVSGPVRGPAHWQADDADVSPDARIMPPVYIGSGAVIEAGAQVGPRAVIGAGCLVAKGAR
CCCCCCCCCCCCCCCCCCCCCCCEECCCEEECCCCEEECCCCCCCCCEEECCHHEECCCC
ISDSVLWDGARVGAGATVRHSVIGFATGIGGGTVENVLLAGWR
CCCCEEECCCCCCCCCHHHHHHHHHEECCCCCCHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]