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The map label for this gene is truD1 [H]

Identifier: 51892102

GI number: 51892102

Start: 1081321

End: 1082475

Strand: Reverse

Name: truD1 [H]

Synonym: STH964

Alternate gene names: 51892102

Gene position: 1082475-1081321 (Counterclockwise)

Preceding gene: 51892103

Following gene: 51892100

Centisome position: 30.35

GC content: 72.47

Gene sequence:

>1155_bases
GTGCGACTGAAGACGACGCCCGAGGACTTTGTGGTGCGGGAGGCCGTGGACCTGCACATCCGCCAGAAGCCGGCCCGGTA
CCGGGTCTACCTGCTGGAGAAGAAAGGCTGGAACACCGCCGACGCGGTCGCCGCCATCGCGCGGGCCCGGCGGCTGCCGC
CCGGCCGCATCCAGTACGGCGGGAAGAAGGACCGGCACGCCCACACGTTCCAGTACGTGACCATCGACCACCCGGCTGAT
CACTCGCTGTCCACGCCCTACTACCGGCTGAAGGCGGTGGGCTACGCCACCGAACCCATGGCGCCCGGCCGGGTGCTGGC
CAATCACTTTGAAGTGACCGTGCGCGAGCTCCGCCCCGAGGAGGCCGCGCGCCTCGTGGACGGCGTCCGGCGCGTGGCCG
CCGCGGGTTTCCCCAATTACTTCGACGACCAGCGGTTCGGCAGCTTCGACCCCCGGCGCGGGTTCATCGCCGAGCAGATG
GCGCAGGGCCGGTGGGAGCAGGCCCTCCAGATCGCACTGACCCACGTCTACCCCGGGGAGAAGAGCAGGGCGAAAGCCCG
CAAGCGCCGGCTGCTGGAGGCCTGGGGCGACTGGGCGACCTGCCTGGACCTGGCGGAGACCGCCTTCGAGCGGCGCTGCT
TCGCCTTGCTGGCGGAGCAGCCGGGCGGGTTCCGGGCGGCCCTGGCCACGGCCCGGCGGGAGGAGCAGGAGATGTGGCTC
TCGGCCTGGCAGGCCTTCCTGTGGAACGAGGTGCTGCGCCGCCTGGTCGCCGCGGCGGCCGGAGGCGACGAACCGCCGGC
GGAGGCGGCGGGGGTCGCGGGGCCGTACCGTTTCGCCCGATCGACGCCGGAGCTGCAGCAGATGGTGATCCCTCTGCCGG
GGCGGGGCATGCGCTTTTCGGACCCCAGGGCCGGCCTGATCCTGGAGGACGTGCTCCGGGAGCGCAGGCTGCGCCCGGCG
CAGCTGGAGGCCGAGCTGCTGCCCGGCCTCTGGCTCAGGAGTTCGCCCCGGGAGGCCTGGGTGATGCCACGGTCGGTGCG
CGTGGACCCGCCGCAGCCGGATGAGCGCTACCCCGGCTTTGAGCGGGTCAGCCTCCGCTTCACGCTGCCCCGGGGCGCCT
ACGCCACCATGTTGATCAAGGCGGCTGCTCACTGA

Upstream 100 bases:

>100_bases
GCGCCTGTGCCTGGGGCGGAACGCGCGTCACCGCTTGCTTCCGTTCCCCGCGGAGGGTACCCTAACGGCGGAACCGCCAG
GAAAGGATGTTGGACACGAC

Downstream 100 bases:

>100_bases
CCGGCCGGGGCTGCCGTGTGAAGGTGCGCAGCCGCCGCCCCCGCAGGTAGCCCACCGGTGCGGCCACGAGCCGCCGCACC
AGGGGCATCACGCCGCCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D 1; tRNA-uridine isomerase D 1 [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRLKTTPEDFVVREAVDLHIRQKPARYRVYLLEKKGWNTADAVAAIARARRLPPGRIQYGGKKDRHAHTFQYVTIDHPAD
HSLSTPYYRLKAVGYATEPMAPGRVLANHFEVTVRELRPEEAARLVDGVRRVAAAGFPNYFDDQRFGSFDPRRGFIAEQM
AQGRWEQALQIALTHVYPGEKSRAKARKRRLLEAWGDWATCLDLAETAFERRCFALLAEQPGGFRAALATARREEQEMWL
SAWQAFLWNEVLRRLVAAAAGGDEPPAEAAGVAGPYRFARSTPELQQMVIPLPGRGMRFSDPRAGLILEDVLRERRLRPA
QLEAELLPGLWLRSSPREAWVMPRSVRVDPPQPDERYPGFERVSLRFTLPRGAYATMLIKAAAH

Sequences:

>Translated_384_residues
MRLKTTPEDFVVREAVDLHIRQKPARYRVYLLEKKGWNTADAVAAIARARRLPPGRIQYGGKKDRHAHTFQYVTIDHPAD
HSLSTPYYRLKAVGYATEPMAPGRVLANHFEVTVRELRPEEAARLVDGVRRVAAAGFPNYFDDQRFGSFDPRRGFIAEQM
AQGRWEQALQIALTHVYPGEKSRAKARKRRLLEAWGDWATCLDLAETAFERRCFALLAEQPGGFRAALATARREEQEMWL
SAWQAFLWNEVLRRLVAAAAGGDEPPAEAAGVAGPYRFARSTPELQQMVIPLPGRGMRFSDPRAGLILEDVLRERRLRPA
QLEAELLPGLWLRSSPREAWVMPRSVRVDPPQPDERYPGFERVSLRFTLPRGAYATMLIKAAAH
>Mature_384_residues
MRLKTTPEDFVVREAVDLHIRQKPARYRVYLLEKKGWNTADAVAAIARARRLPPGRIQYGGKKDRHAHTFQYVTIDHPAD
HSLSTPYYRLKAVGYATEPMAPGRVLANHFEVTVRELRPEEAARLVDGVRRVAAAGFPNYFDDQRFGSFDPRRGFIAEQM
AQGRWEQALQIALTHVYPGEKSRAKARKRRLLEAWGDWATCLDLAETAFERRCFALLAEQPGGFRAALATARREEQEMWL
SAWQAFLWNEVLRRLVAAAAGGDEPPAEAAGVAGPYRFARSTPELQQMVIPLPGRGMRFSDPRAGLILEDVLRERRLRPA
QLEAELLPGLWLRSSPREAWVMPRSVRVDPPQPDERYPGFERVSLRFTLPRGAYATMLIKAAAH

Specific function: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Homo sapiens, GI50727002, Length=286, Percent_Identity=22.027972027972, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324817, Length=254, Percent_Identity=26.7716535433071, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 43614; Mature: 43614

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50984 TRUD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKTTPEDFVVREAVDLHIRQKPARYRVYLLEKKGWNTADAVAAIARARRLPPGRIQYG
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC
GKKDRHAHTFQYVTIDHPADHSLSTPYYRLKAVGYATEPMAPGRVLANHFEVTVRELRPE
CCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCHH
EAARLVDGVRRVAAAGFPNYFDDQRFGSFDPRRGFIAEQMAQGRWEQALQIALTHVYPGE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KSRAKARKRRLLEAWGDWATCLDLAETAFERRCFALLAEQPGGFRAALATARREEQEMWL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SAWQAFLWNEVLRRLVAAAAGGDEPPAEAAGVAGPYRFARSTPELQQMVIPLPGRGMRFS
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHCCCHHHHHEEECCCCCCCCCC
DPRAGLILEDVLRERRLRPAQLEAELLPGLWLRSSPREAWVMPRSVRVDPPQPDERYPGF
CCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHEECCCCEECCCCCCCCCCCCC
ERVSLRFTLPRGAYATMLIKAAAH
EEEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRLKTTPEDFVVREAVDLHIRQKPARYRVYLLEKKGWNTADAVAAIARARRLPPGRIQYG
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC
GKKDRHAHTFQYVTIDHPADHSLSTPYYRLKAVGYATEPMAPGRVLANHFEVTVRELRPE
CCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCHH
EAARLVDGVRRVAAAGFPNYFDDQRFGSFDPRRGFIAEQMAQGRWEQALQIALTHVYPGE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KSRAKARKRRLLEAWGDWATCLDLAETAFERRCFALLAEQPGGFRAALATARREEQEMWL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SAWQAFLWNEVLRRLVAAAAGGDEPPAEAAGVAGPYRFARSTPELQQMVIPLPGRGMRFS
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHCCCHHHHHEEECCCCCCCCCC
DPRAGLILEDVLRERRLRPAQLEAELLPGLWLRSSPREAWVMPRSVRVDPPQPDERYPGF
CCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHEECCCCEECCCCCCCCCCCCC
ERVSLRFTLPRGAYATMLIKAAAH
EEEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA