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The map label for this gene is fadR [H]

Identifier: 51892099

GI number: 51892099

Start: 1078831

End: 1079454

Strand: Reverse

Name: fadR [H]

Synonym: STH961

Alternate gene names: 51892099

Gene position: 1079454-1078831 (Counterclockwise)

Preceding gene: 51892100

Following gene: 51892098

Centisome position: 30.27

GC content: 71.47

Gene sequence:

>624_bases
GTGCCCAGGGTGAGTCCGGCGCACATGGAGCGGCGGCGCGAGGCCATCCTCAACGCCGCCATGGAGGTGTTCATCGCCAA
GGGCTATCAGGTGGCCACCGTGGGCGACATCGCCCAGCAGGCCGGGCTCAGCGTCGGCGCGATCTACCGGTACTTTCCCA
CCAAGGCCGACCTGATGCTCGCGCTGGTGCGCGAGCGGCTGGGCCGGGCGCCCGCGCTCTTCGCCAGGCTGACGGCCCGC
GTGGAGGATCCGTGGGAGCGGCTGGTGCGATGCGTCGAACTGTTCACCGCCGCCCTCCGGGTGCGCCACCCGGGCACCGG
GCGGCTGCTCCTGGTGACCATGGCGGAGGCGGTGCAGAACGGCGAGGTGCGCCGGGGACTTCACGACCGGTTCGCCGGGC
TGGCGGACTACGTCGCGGGCATCATCGCCGAGGGCGTCGCCCGGGGCCGCTTCCGGCCGGACGTCGACCCCCGCACCGTG
GCCGCGCTGCTGCTGTCCATGGCCGACGGGGTGGCGGTCTACTGGGTGACCGGCGCGCCGGACCTGGAACTGAACGCCAT
GGGGCAGAGCCTGGTGGCGATGCTCCGTTCCTATCTGCTTCCTGAACCTCTATTGAAGGAGTGA

Upstream 100 bases:

>100_bases
ATTCGCGGTTGAGGGGCTGCCCCCTCCCCGGCCTGTGGGCCCCTCCGTCCCCCGGGAGGGCTTCGCCCGCTGGGCCGCGG
TTCTGAAGGAGTGGATCCCC

Downstream 100 bases:

>100_bases
ACCGTATGGAGCGACGGGTAGTGGTCACCGGCATGGGGCTGATCTCGCCCCTGGGCAACAGCGTCCGGGCCAACTGGGAG
GCGGCGGTGGCGGGCCGCTC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MPRVSPAHMERRREAILNAAMEVFIAKGYQVATVGDIAQQAGLSVGAIYRYFPTKADLMLALVRERLGRAPALFARLTAR
VEDPWERLVRCVELFTAALRVRHPGTGRLLLVTMAEAVQNGEVRRGLHDRFAGLADYVAGIIAEGVARGRFRPDVDPRTV
AALLLSMADGVAVYWVTGAPDLELNAMGQSLVAMLRSYLLPEPLLKE

Sequences:

>Translated_207_residues
MPRVSPAHMERRREAILNAAMEVFIAKGYQVATVGDIAQQAGLSVGAIYRYFPTKADLMLALVRERLGRAPALFARLTAR
VEDPWERLVRCVELFTAALRVRHPGTGRLLLVTMAEAVQNGEVRRGLHDRFAGLADYVAGIIAEGVARGRFRPDVDPRTV
AALLLSMADGVAVYWVTGAPDLELNAMGQSLVAMLRSYLLPEPLLKE
>Mature_206_residues
PRVSPAHMERRREAILNAAMEVFIAKGYQVATVGDIAQQAGLSVGAIYRYFPTKADLMLALVRERLGRAPALFARLTARV
EDPWERLVRCVELFTAALRVRHPGTGRLLLVTMAEAVQNGEVRRGLHDRFAGLADYVAGIIAEGVARGRFRPDVDPRTVA
ALLLSMADGVAVYWVTGAPDLELNAMGQSLVAMLRSYLLPEPLLKE

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787904, Length=161, Percent_Identity=27.3291925465839, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22736; Mature: 22605

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVSPAHMERRREAILNAAMEVFIAKGYQVATVGDIAQQAGLSVGAIYRYFPTKADLML
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCHHHHHHHCCCHHHHHH
ALVRERLGRAPALFARLTARVEDPWERLVRCVELFTAALRVRHPGTGRLLLVTMAEAVQN
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
GEVRRGLHDRFAGLADYVAGIIAEGVARGRFRPDVDPRTVAALLLSMADGVAVYWVTGAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCC
DLELNAMGQSLVAMLRSYLLPEPLLKE
CCHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
PRVSPAHMERRREAILNAAMEVFIAKGYQVATVGDIAQQAGLSVGAIYRYFPTKADLML
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCHHHHHHHCCCHHHHHH
ALVRERLGRAPALFARLTARVEDPWERLVRCVELFTAALRVRHPGTGRLLLVTMAEAVQN
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
GEVRRGLHDRFAGLADYVAGIIAEGVARGRFRPDVDPRTVAALLLSMADGVAVYWVTGAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCC
DLELNAMGQSLVAMLRSYLLPEPLLKE
CCHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]