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The map label for this gene is yebQ [H]

Identifier: 51892028

GI number: 51892028

Start: 1006209

End: 1007633

Strand: Reverse

Name: yebQ [H]

Synonym: STH890

Alternate gene names: 51892028

Gene position: 1007633-1006209 (Counterclockwise)

Preceding gene: 51892043

Following gene: 51892024

Centisome position: 28.26

GC content: 72.63

Gene sequence:

>1425_bases
TTGACCATTACGTCCAGGGAGCAAAAGGCCGCACCGACCGGGGAAGGCCGGGCGGCAGTCAACGACAGCTACCGGTGGCT
TGTCCTCATCGTGGCCGGCACCAGCGCCTTCATGGGGGCGCTGGACGGCAGCATCATCAACATCATCATCCCCCAGATCC
AGGCGCAGTACCAGGCGACCCTCGGCGACATCAGCTGGGTCTCCACCGCCTACCTGGTGACCATCTCGTCGCTGCTGCTT
TCCGCGGGACGGCTCGGCGACATGTGGGGATACCGGCCGGTCTTCGGCGCGGGGTTCATCGTCTTCGGCCTCGGCTCGCT
CCTGTGCGGCCTCGCCCCCACCCTGCCGACCCTCATCGGCGGCCGGCTGGTGCAGGGGGTCGGCGCGGCCGTCATGATGG
CGCTCTCCCCCGCCCTCATCACCACCACGTTCCCCGGCCGGGAGCGGGGCCGGGCGCTGGGGATGCAGGCGACCCTGACC
TTCACCGGCCTCACCCTCGGCCCCAGCCTGGGCGGGTTCATCGCGGGCCGGTGGGGATGGCACTGGGTCTTCCTGATCAA
CTTGCCGGTCGCGGCGGTCGGGGCCGTCCTGGCCTACACGCAGCTGCGCCCCACCGAGCGGCGGAGCGGCCAGGCCTTCG
ACTTCGCCGGGGCGCTGCTGTTCGCGGCGGGCCTGGCCTCGGTTCTACTGGCGCTCAGCCAGGCCGAGACCTGGGGCTGG
GGCGACCTGCGCACCCGGCTGCTCCTCGCCGGCGGCGCCCTGCTGCTCCTGCTCTTCCTCTGGCAGGAGCGGCGCGCCGC
CCAGCCGATGCTGCCGCTGTGGATGTTCCGGGTGCCGGCCTTCACCGGCGGGGTCGCCGCGGCGCTCCTGCAGTTCTCCG
CCACGTTTGTCCTCACGTTCCTGCTGCCCTTCTACCTGCAGCAGTTCCGCGGGCTCAGCCCCAGCGCCGCGGGGGCCGTG
ATGACGGCGCAGCCCGCCGCCATGGTGGCCGTGGCCGGGCTGGCCGGCTGGCTCTCCGACCGGATCGGCACCCGCATCCC
CGCCACGGCGGGCATGGCCGCCATCGCCTGCGGGCTCTGGCTGGTGTCCCGGGCCGGCGCCGCGACCCCGGTCACGCAGG
TGGCGCTCTGCCTGGCCCTGATCGGCCTGGGCGCCGGCTTCTTCAACCCGCCCAACAACAGCTCCATCATGAGCGCTGCG
CCCTGGGACCGGCAGGGGGTGGCGGCCGCCCTGCTGGCCGCGGCCCGCAACGTGGGCATGGTCACGGGCATCACCATCGC
CAGCACCCTGTTCGCCCACCTGAGCCAGCGCATGGACTTCCTCGCCGCCTTCCGCACCACACTGGCGGTCCCGGTGGGCC
TGGCGGTGACCGGCGCCCTGCTCTCGCTGGTGCGGCCGACGGTGGCGAAGGATGCCGACAAATAG

Upstream 100 bases:

>100_bases
GCCTGCGCGTGCTGACAAGCCTCCCTCGGTTCGGACTGCAGGCGGGAAATCGGCCGGTTCAGGGCGAACAGGATGATCCC
GGAATCTGCTGCGGTGGAGG

Downstream 100 bases:

>100_bases
CCGGCGGTCTGGCGACCGCCGGCCGTTGACGCTTACTTAATGATGGTGACCTTTCATGTTCTGGCGCGCCCAGTCCAGGG
CCAGGAGCAGGCCCAGGAGG

Product: multidrug efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTITSREQKAAPTGEGRAAVNDSYRWLVLIVAGTSAFMGALDGSIINIIIPQIQAQYQATLGDISWVSTAYLVTISSLLL
SAGRLGDMWGYRPVFGAGFIVFGLGSLLCGLAPTLPTLIGGRLVQGVGAAVMMALSPALITTTFPGRERGRALGMQATLT
FTGLTLGPSLGGFIAGRWGWHWVFLINLPVAAVGAVLAYTQLRPTERRSGQAFDFAGALLFAAGLASVLLALSQAETWGW
GDLRTRLLLAGGALLLLLFLWQERRAAQPMLPLWMFRVPAFTGGVAAALLQFSATFVLTFLLPFYLQQFRGLSPSAAGAV
MTAQPAAMVAVAGLAGWLSDRIGTRIPATAGMAAIACGLWLVSRAGAATPVTQVALCLALIGLGAGFFNPPNNSSIMSAA
PWDRQGVAAALLAAARNVGMVTGITIASTLFAHLSQRMDFLAAFRTTLAVPVGLAVTGALLSLVRPTVAKDADK

Sequences:

>Translated_474_residues
MTITSREQKAAPTGEGRAAVNDSYRWLVLIVAGTSAFMGALDGSIINIIIPQIQAQYQATLGDISWVSTAYLVTISSLLL
SAGRLGDMWGYRPVFGAGFIVFGLGSLLCGLAPTLPTLIGGRLVQGVGAAVMMALSPALITTTFPGRERGRALGMQATLT
FTGLTLGPSLGGFIAGRWGWHWVFLINLPVAAVGAVLAYTQLRPTERRSGQAFDFAGALLFAAGLASVLLALSQAETWGW
GDLRTRLLLAGGALLLLLFLWQERRAAQPMLPLWMFRVPAFTGGVAAALLQFSATFVLTFLLPFYLQQFRGLSPSAAGAV
MTAQPAAMVAVAGLAGWLSDRIGTRIPATAGMAAIACGLWLVSRAGAATPVTQVALCLALIGLGAGFFNPPNNSSIMSAA
PWDRQGVAAALLAAARNVGMVTGITIASTLFAHLSQRMDFLAAFRTTLAVPVGLAVTGALLSLVRPTVAKDADK
>Mature_473_residues
TITSREQKAAPTGEGRAAVNDSYRWLVLIVAGTSAFMGALDGSIINIIIPQIQAQYQATLGDISWVSTAYLVTISSLLLS
AGRLGDMWGYRPVFGAGFIVFGLGSLLCGLAPTLPTLIGGRLVQGVGAAVMMALSPALITTTFPGRERGRALGMQATLTF
TGLTLGPSLGGFIAGRWGWHWVFLINLPVAAVGAVLAYTQLRPTERRSGQAFDFAGALLFAAGLASVLLALSQAETWGWG
DLRTRLLLAGGALLLLLFLWQERRAAQPMLPLWMFRVPAFTGGVAAALLQFSATFVLTFLLPFYLQQFRGLSPSAAGAVM
TAQPAAMVAVAGLAGWLSDRIGTRIPATAGMAAIACGLWLVSRAGAATPVTQVALCLALIGLGAGFFNPPNNSSIMSAAP
WDRQGVAAALLAAARNVGMVTGITIASTLFAHLSQRMDFLAAFRTTLAVPVGLAVTGALLSLVRPTVAKDADK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=405, Percent_Identity=32.3456790123457, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1790195, Length=321, Percent_Identity=30.5295950155763, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788392, Length=419, Percent_Identity=30.5489260143198, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789042, Length=405, Percent_Identity=25.4320987654321, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788710, Length=423, Percent_Identity=26.4775413711584, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790146, Length=135, Percent_Identity=28.8888888888889, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324954, Length=417, Percent_Identity=26.378896882494, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319770, Length=438, Percent_Identity=24.2009132420091, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6323735, Length=315, Percent_Identity=25.0793650793651, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=346, Percent_Identity=23.6994219653179, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321663, Length=163, Percent_Identity=28.2208588957055, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=257, Percent_Identity=26.8482490272374, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49434; Mature: 49303

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITSREQKAAPTGEGRAAVNDSYRWLVLIVAGTSAFMGALDGSIINIIIPQIQAQYQAT
CCCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCHHHHHHHCCCEEEHHHHHHHHHHHHH
LGDISWVSTAYLVTISSLLLSAGRLGDMWGYRPVFGAGFIVFGLGSLLCGLAPTLPTLIG
HCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLVQGVGAAVMMALSPALITTTFPGRERGRALGMQATLTFTGLTLGPSLGGFIAGRWGW
HHHHHHHHHHHHHHHCCHHEEECCCCHHHCCCCCCEEEEEEECEEECCCCCCHHCCCCCE
HWVFLINLPVAAVGAVLAYTQLRPTERRSGQAFDFAGALLFAAGLASVLLALSQAETWGW
EEEEEEECCHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GDLRTRLLLAGGALLLLLFLWQERRAAQPMLPLWMFRVPAFTGGVAAALLQFSATFVLTF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPFYLQQFRGLSPSAAGAVMTAQPAAMVAVAGLAGWLSDRIGTRIPATAGMAAIACGLW
HHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LVSRAGAATPVTQVALCLALIGLGAGFFNPPNNSSIMSAAPWDRQGVAAALLAAARNVGM
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCH
VTGITIASTLFAHLSQRMDFLAAFRTTLAVPVGLAVTGALLSLVRPTVAKDADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TITSREQKAAPTGEGRAAVNDSYRWLVLIVAGTSAFMGALDGSIINIIIPQIQAQYQAT
CCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCHHHHHHHCCCEEEHHHHHHHHHHHHH
LGDISWVSTAYLVTISSLLLSAGRLGDMWGYRPVFGAGFIVFGLGSLLCGLAPTLPTLIG
HCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLVQGVGAAVMMALSPALITTTFPGRERGRALGMQATLTFTGLTLGPSLGGFIAGRWGW
HHHHHHHHHHHHHHHCCHHEEECCCCHHHCCCCCCEEEEEEECEEECCCCCCHHCCCCCE
HWVFLINLPVAAVGAVLAYTQLRPTERRSGQAFDFAGALLFAAGLASVLLALSQAETWGW
EEEEEEECCHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GDLRTRLLLAGGALLLLLFLWQERRAAQPMLPLWMFRVPAFTGGVAAALLQFSATFVLTF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPFYLQQFRGLSPSAAGAVMTAQPAAMVAVAGLAGWLSDRIGTRIPATAGMAAIACGLW
HHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LVSRAGAATPVTQVALCLALIGLGAGFFNPPNNSSIMSAAPWDRQGVAAALLAAARNVGM
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCH
VTGITIASTLFAHLSQRMDFLAAFRTTLAVPVGLAVTGALLSLVRPTVAKDADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]