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The map label for this gene is hflK [H]

Identifier: 51598464

GI number: 51598464

Start: 203717

End: 204652

Strand: Direct

Name: hflK [H]

Synonym: BG0203

Alternate gene names: 51598464

Gene position: 203717-204652 (Clockwise)

Preceding gene: 51598463

Following gene: 51598465

Centisome position: 22.53

GC content: 27.67

Gene sequence:

>936_bases
ATGTTTGACATAAAACAAATTTTTAATAAAACTTATGAATATTTAGTAATTATTATTACTTTATTACTAATATTAATAAT
AATTATTGCAAACATATTCATAGTCGGGCCATCAGAAGAAGCAATTGTACTTCGCCTTGGCAAGCTTAACAGAACTCTTG
ATTCAGGAATACATGTTAAAATTCCGTTAATTGAAGAAAAATTTATCGTACCTGTAAAAATAGTCCAAGAAATTAAATTT
GGATTTCTAATGTCTCCAAACGATTTTAGAAAAAATGATAATTCAGACAATGAGGGTATGATTATCACTGGAGATTTAAA
TATCATAAATATTGAATGGTTAGTGCAATACAAAATAAGAGATCCTTACTCATTTAAATTTAAAGTAGAAGATCCCGAGA
CAACAATCAAGGATATTGCAAAATCATCAATGAATAGATTAATTGGGGACAATACTATTTTTGAAATAATCAATGATAAC
AGAGTGGGAGTTACAGAAGGTGTGAAATCTTCTATGAATGAAATAATAGATAATTATAATTTAGGAATTGATGTAGTGCA
AGTACAAATTAGAAATGCCCTGCCGCCAAAAGGAAAAGTTTACGAAGCTTTTGAAGATGTAAACATTGCCATTCAAGACA
AAAATAAATACATAAACGAGGGAAAAAAAGAATTTAATCAAATAGTTCCCAAAATTAAAGGTGAAGCATTAAAGGTTATT
GAAGAAGCCAGAGGATACAAAGAAAGCAGAATAAACAATGCATTAGCAGACACAGAAATTTTTAATGCCATACTAGACGC
TTACTTAAAAAATCCAGATATTACAAAAGAAAGGCTTTACAATGAAACTATGAAGGAAATACTTGAAAACAAAGATAATA
TTGAATTAATTGACAAAAACTTAAAAAATTTTCTACCATTTAAAGAGGTAAAATAA

Upstream 100 bases:

>100_bases
CAGAATAATAAAATTGAAATAATAACCTTTATTAAATCTAAAAATTAGCGATAAAATTCGCTTACAAAATTAAAATAATT
AAAAATATTGGGAGAAACAA

Downstream 100 bases:

>100_bases
ATGAAATTTATAATAAATCTTTTATTATCTACTGTAAAAATTACAACCTTTGCAATAATAGTTTGTTTGACTATTTTGTC
TATTTTCCAACCAATTTATA

Product: lambda CII stability-governing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MFDIKQIFNKTYEYLVIIITLLLILIIIIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVKIPLIEEKFIVPVKIVQEIKF
GFLMSPNDFRKNDNSDNEGMIITGDLNIINIEWLVQYKIRDPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDN
RVGVTEGVKSSMNEIIDNYNLGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGKKEFNQIVPKIKGEALKVI
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKNLKNFLPFKEVK

Sequences:

>Translated_311_residues
MFDIKQIFNKTYEYLVIIITLLLILIIIIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVKIPLIEEKFIVPVKIVQEIKF
GFLMSPNDFRKNDNSDNEGMIITGDLNIINIEWLVQYKIRDPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDN
RVGVTEGVKSSMNEIIDNYNLGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGKKEFNQIVPKIKGEALKVI
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKNLKNFLPFKEVK
>Mature_311_residues
MFDIKQIFNKTYEYLVIIITLLLILIIIIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVKIPLIEEKFIVPVKIVQEIKF
GFLMSPNDFRKNDNSDNEGMIITGDLNIINIEWLVQYKIRDPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDN
RVGVTEGVKSSMNEIIDNYNLGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGKKEFNQIVPKIKGEALKVI
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKNLKNFLPFKEVK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=271, Percent_Identity=28.0442804428044, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 35815; Mature: 35815

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIKQIFNKTYEYLVIIITLLLILIIIIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEHHHHHHHCCCCEEE
IPLIEEKFIVPVKIVQEIKFGFLMSPNDFRKNDNSDNEGMIITGDLNIINIEWLVQYKIR
EEEECCCCCHHHHHHHHHHHCEEECCCHHCCCCCCCCCCEEEECCCEEEEEEEEEEEEEC
DPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDNRVGVTEGVKSSMNEIIDNYN
CCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
LGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGKKEFNQIVPKIKGEALKVI
CCEEEEEEEEHHCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHH
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
LKNFLPFKEVK
HHHCCCCCCCC
>Mature Secondary Structure
MFDIKQIFNKTYEYLVIIITLLLILIIIIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEHHHHHHHCCCCEEE
IPLIEEKFIVPVKIVQEIKFGFLMSPNDFRKNDNSDNEGMIITGDLNIINIEWLVQYKIR
EEEECCCCCHHHHHHHHHHHCEEECCCHHCCCCCCCCCCEEEECCCEEEEEEEEEEEEEC
DPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDNRVGVTEGVKSSMNEIIDNYN
CCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
LGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGKKEFNQIVPKIKGEALKVI
CCEEEEEEEEHHCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHH
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
LKNFLPFKEVK
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]