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The map label for this gene is ung [H]

Identifier: 51598314

GI number: 51598314

Start: 49183

End: 49854

Strand: Direct

Name: ung [H]

Synonym: BG0052

Alternate gene names: 51598314

Gene position: 49183-49854 (Clockwise)

Preceding gene: 51598312

Following gene: 51598323

Centisome position: 5.44

GC content: 28.12

Gene sequence:

>672_bases
ATGAAAGTAAAAATTGAAGAATCTTGGAAAGAAGTTTTAAACAATGAATTTAATAAAGGATACTTTAAAAAGCTTGTGAA
GTTCATAAAACATGAATATAAAACAAAAAAAGGTAAAATATTCCCTCCTCCAAAACTTATATTCAATGCTTTTGATTCTT
TGCCATTTAAAGACATAAAGGTGGTAATAATTGGACAAGATCCATATCATGGAAAAAACCAAGCAAATGGACTTGCTTTT
TCTGTGGATTCAGAAATCAAAATTCCACCGTCTTTGCAAAACATATTTAAAGAAATAGAAAAAAGTTTAAAAATAAAAAC
ACTCCCAAACGGAGATTTAAAAAGATGGGCAATTCAAGGTGTATTTTTAATAAATACAATCTTAACGGTCGAAGAAGGCA
AACCTTCTTCTCATAAAGATATTGGGTGGGAAATTTTTACAGATGAAGTAATAAAAATAATCTCGAAAAATTTGGAAAAT
ATTGTATTTATGCTTTGGGGCAATTTAGCAAGAAGTAAAAAAAAGCTCATAAACCCAACAAAGCATCTAATTCTTGAAAC
AAGCCACCCATCTCCATATTCAGCAAACAATGGATTTTTAGGATCAAACCATTTTAGCGATGCTTTAAATTATTTAAAAC
AACACAATAAAAATAAAATAAACTTTCAATAA

Upstream 100 bases:

>100_bases
TAATACATCATTATCCATAATAAAAATCAAATTTCAAAAATAGTAAAGTCTTACCTTCAATACATTTCAAATTAAAAACT
ATTTCTTATATAATACAAAA

Downstream 100 bases:

>100_bases
AATTAATAATAGTTATGATTTAAAATTCTTTTACGTAAAGAGTCAACTCTTTGCGTAAAAGAGTGCTATAATATAGCACA
ACAGTAATCAATTTAAATTA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKVKIEESWKEVLNNEFNKGYFKKLVKFIKHEYKTKKGKIFPPPKLIFNAFDSLPFKDIKVVIIGQDPYHGKNQANGLAF
SVDSEIKIPPSLQNIFKEIEKSLKIKTLPNGDLKRWAIQGVFLINTILTVEEGKPSSHKDIGWEIFTDEVIKIISKNLEN
IVFMLWGNLARSKKKLINPTKHLILETSHPSPYSANNGFLGSNHFSDALNYLKQHNKNKINFQ

Sequences:

>Translated_223_residues
MKVKIEESWKEVLNNEFNKGYFKKLVKFIKHEYKTKKGKIFPPPKLIFNAFDSLPFKDIKVVIIGQDPYHGKNQANGLAF
SVDSEIKIPPSLQNIFKEIEKSLKIKTLPNGDLKRWAIQGVFLINTILTVEEGKPSSHKDIGWEIFTDEVIKIISKNLEN
IVFMLWGNLARSKKKLINPTKHLILETSHPSPYSANNGFLGSNHFSDALNYLKQHNKNKINFQ
>Mature_223_residues
MKVKIEESWKEVLNNEFNKGYFKKLVKFIKHEYKTKKGKIFPPPKLIFNAFDSLPFKDIKVVIIGQDPYHGKNQANGLAF
SVDSEIKIPPSLQNIFKEIEKSLKIKTLPNGDLKRWAIQGVFLINTILTVEEGKPSSHKDIGWEIFTDEVIKIISKNLEN
IVFMLWGNLARSKKKLINPTKHLILETSHPSPYSANNGFLGSNHFSDALNYLKQHNKNKINFQ

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=224, Percent_Identity=44.1964285714286, Blast_Score=200, Evalue=1e-51,
Organism=Homo sapiens, GI6224979, Length=224, Percent_Identity=44.1964285714286, Blast_Score=199, Evalue=1e-51,
Organism=Escherichia coli, GI1788934, Length=218, Percent_Identity=46.3302752293578, Blast_Score=205, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17556304, Length=218, Percent_Identity=48.1651376146789, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6323620, Length=217, Percent_Identity=42.8571428571429, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 25662; Mature: 25662

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKIEESWKEVLNNEFNKGYFKKLVKFIKHEYKTKKGKIFPPPKLIFNAFDSLPFKDIK
CEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEE
VVIIGQDPYHGKNQANGLAFSVDSEIKIPPSLQNIFKEIEKSLKIKTLPNGDLKRWAIQG
EEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCEEEECCCCCHHHHHHHH
VFLINTILTVEEGKPSSHKDIGWEIFTDEVIKIISKNLENIVFMLWGNLARSKKKLINPT
HHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KHLILETSHPSPYSANNGFLGSNHFSDALNYLKQHNKNKINFQ
HHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKVKIEESWKEVLNNEFNKGYFKKLVKFIKHEYKTKKGKIFPPPKLIFNAFDSLPFKDIK
CEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEE
VVIIGQDPYHGKNQANGLAFSVDSEIKIPPSLQNIFKEIEKSLKIKTLPNGDLKRWAIQG
EEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCEEEECCCCCHHHHHHHH
VFLINTILTVEEGKPSSHKDIGWEIFTDEVIKIISKNLENIVFMLWGNLARSKKKLINPT
HHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KHLILETSHPSPYSANNGFLGSNHFSDALNYLKQHNKNKINFQ
HHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA