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The map label for this gene is fepA [C]

Identifier: 51598027

GI number: 51598027

Start: 4433551

End: 4435596

Strand: Reverse

Name: fepA [C]

Synonym: YPTB3737

Alternate gene names: 51598027

Gene position: 4435596-4433551 (Counterclockwise)

Preceding gene: 51598029

Following gene: 51598024

Centisome position: 93.49

GC content: 50.68

Gene sequence:

>2046_bases
ATGATATCTGGGAAAAATAAAGTCTGTAAAAAGAAGTTATTAGCGTGTGCGGTTACTTCGGCTATTTCTGCCTTTGCTTC
AAATGCCATTGCCGATACTACGAGTCTGGCTGCAATGAATCGCTCAGCCATTAATATATCAAGCACGCATAACAGTAATA
AAAAACTCAATGACGCTGATGTCATCACGGTAACAGCCCCTCTGTATTCGCCACTGGTGGTTGCCACATCGCCTAAAGTG
CCCCGCCAGCCAGTACCGGCCAGTGACGGTGCTGATTATCTGAGGACCATTCCCGGTTTTTCACTCGTCCGTAACGGGGG
GACCAATGGTGATGTGGTGTTCCGTGGCATGTTCGGCTCACGGCTAAAAATTCTGACCGATGGTGCTGAGATTTTGGGTA
CCTGCCCATCGCGAATGGATGCGCCAACCTCGTATATTTCACCAGAAAATTTTGATCTACTCACGGTCGTCAAAGGGCCG
CAATCGGTGCTGTGGGGGCCGGGGGCTTCTGCCGGGACCATTTTATTTGAACGGGAGCGCCCACATTTTGACCAGTCTGG
CGTCAAAGGTAATGCCAGTGTGTTAGCCGGTTCTAATGGGCGCTGGGATAAAAATCTTGATGCCAGTTTGGGTAATGAGC
AGGGCTATCTGCGGATGATGGGGAATCAGTCTCGAGCTGCTGATTATAAAGACGGTAACAATGTCCGCGTGCCCTCTCAA
TGGGATAAGTGGAATGCCGATATGGCGTTGGGCTGGACACCCGATACCGATACATTACTTGAGCTGTCGGTAGGAAAAGG
GAATGGTGAATCCCGCTATGGCGGTCGCGGTATGGATGGTTCTCAGTTCCTGCGTGAGAGCCTGGCGGCCCGCGTTGAGA
AAAGTAATATTGGCGAGGTGCTGGATAAGATCGAAGCCAAAATTAACTACACCTACGTAAATCATATTATGGATAACAAG
ACCTTACGTACCCCACCGATGATGGCGATGTCTAGCAATCTGGACCGGCGGATGCTCGGCGGTCGGGTCATGGGGACCTG
GCTGTGGCAGGACCTAAAGCTGGACGCGGGTACCGATATGCAAACCAATACACACCGCAAGAATAAACAGGGGAACTGGG
ATAAAAACGCCCGTTTTATGAATAACGGGGTGTTCGGTGAGTTAACCTGGGCGGCAAGTGAACAAAATAAACTGATCAGC
GGGGCGCGTCTTGACCGTCACCAAGTGACGAATTATACCCGCGCAGGTGAGCCGACGCGCTCTGCTACCCTCCCCGCTGC
CTTTATGCGTGTTGAGCATAATCTGGCTAATGCACCGGTGATGTTGTATGCCGGCTTGGGGCATACCGAGCGTTTTCCTG
ACTATTGGGAACTGTTTTCGCCAAAATTCGGGCCAGCAGGCTCTACTAGCGCCTTTGAGGGTGTAAAAAGCGAAAAAACC
ACGCAGATTGATATCGGTGGCCAATACAGCGGTGAACAATTTAGGGGGTGGCTCTCCGCTTATATTGGCCGGGTTAATGA
TTTTATCCTGTTTAAATATGATCCAAAAAATCTACGCATCAGCCAGGCCGATAATATTAACGCAACCATTATGGGCGGCG
AGATGGGGATGGAATATGCCCTCACCCCGTATTGGAAGGCTGATGCCAGTCTGGCTTATGCCTGGGGGGAAAATACCCGT
GATAACCGGCCATTGCCGCAAATTCCACCACTTGAGGCGCGGTTAGGGCTGACATTTGAAGCAGGCGACTGGAGCAGTTC
CGCCTTATGGCGTTTGGTCAATAGCCAGCACCGGGTGGCGATCAACGAAGGGAATGTCGTCGGTAAAGATTTTTCCAGCA
GTGCGGGGTTCGGCGTACTGTCGGCTAACGTCGCCTATAAGGTGAATAAGCAAGTGAAGTTAAGTAGCGGCATCGATAAT
TTGCTGAATAAGGCTTACAGCGAACATCTTAATCTGGCGGGTAATAGCGGTTTTGGTTATTCAGTTAATACCCCTCTGAA
TGAGCCTGGCCGCACTCTCTGGGCAAAGCTAAACCTAACATTCTAA

Upstream 100 bases:

>100_bases
GATCCAATTATTCCTGATAGAAAGCGAAAAAATATAAAACCACTTTTCTGGCATGGGTAAATATCCCGCCGGAACAATGT
GTATTGCCTAAGGGGAAGTA

Downstream 100 bases:

>100_bases
GGGGCTGAATGCGCTAGCAGAACGTGGCAGGCCATGGCTTGCCACGTTAATAACAATTAATACCAATAACAATTAATACC
AATAACAATTAATACCAATA

Product: iron siderophore receptor/tonB dependent transporter

Products: NA

Alternate protein names: NB-Dependent Receptor; NB Dependent Receptor; Outer Membrane Copper Receptor; Nb-Dependent Receptor; NB-Dependent Receptor Protein; Outer Membrane Copper Receptor OprC; Outer Membrane Protein C; Outer Membrane Receptor Protein; Outer Membrane Protein OprC; Outer Membrane Protein; Outer Membrane Protein OprC Complement; Outer Membrane Insertion C-Terminal Signal; NB-Dependent Outer Membrane Receptor; Outer Membrane Protein Nosa; B12 Family nB-Dependent Receptor; Nb-Dependent Copper Receptor; N-B Dependent Receptor; NB-Dependent Receptor Plug Domain-Containing; Outer Membrane Receptor Protein Mostly Fe Transport; NosA Protein; NB-Dependent Copper Receptor Protein; Membrane Receptor Protein; NB-Dependent Receptor Domain Protein; Outer Membrane Receptor Proteins

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MISGKNKVCKKKLLACAVTSAISAFASNAIADTTSLAAMNRSAINISSTHNSNKKLNDADVITVTAPLYSPLVVATSPKV
PRQPVPASDGADYLRTIPGFSLVRNGGTNGDVVFRGMFGSRLKILTDGAEILGTCPSRMDAPTSYISPENFDLLTVVKGP
QSVLWGPGASAGTILFERERPHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNVRVPSQ
WDKWNADMALGWTPDTDTLLELSVGKGNGESRYGGRGMDGSQFLRESLAARVEKSNIGEVLDKIEAKINYTYVNHIMDNK
TLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLDAGTDMQTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQNKLIS
GARLDRHQVTNYTRAGEPTRSATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGVKSEKT
TQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEMGMEYALTPYWKADASLAYAWGENTR
DNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNSQHRVAINEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLSSGIDN
LLNKAYSEHLNLAGNSGFGYSVNTPLNEPGRTLWAKLNLTF

Sequences:

>Translated_681_residues
MISGKNKVCKKKLLACAVTSAISAFASNAIADTTSLAAMNRSAINISSTHNSNKKLNDADVITVTAPLYSPLVVATSPKV
PRQPVPASDGADYLRTIPGFSLVRNGGTNGDVVFRGMFGSRLKILTDGAEILGTCPSRMDAPTSYISPENFDLLTVVKGP
QSVLWGPGASAGTILFERERPHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNVRVPSQ
WDKWNADMALGWTPDTDTLLELSVGKGNGESRYGGRGMDGSQFLRESLAARVEKSNIGEVLDKIEAKINYTYVNHIMDNK
TLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLDAGTDMQTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQNKLIS
GARLDRHQVTNYTRAGEPTRSATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGVKSEKT
TQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEMGMEYALTPYWKADASLAYAWGENTR
DNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNSQHRVAINEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLSSGIDN
LLNKAYSEHLNLAGNSGFGYSVNTPLNEPGRTLWAKLNLTF
>Mature_681_residues
MISGKNKVCKKKLLACAVTSAISAFASNAIADTTSLAAMNRSAINISSTHNSNKKLNDADVITVTAPLYSPLVVATSPKV
PRQPVPASDGADYLRTIPGFSLVRNGGTNGDVVFRGMFGSRLKILTDGAEILGTCPSRMDAPTSYISPENFDLLTVVKGP
QSVLWGPGASAGTILFERERPHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNVRVPSQ
WDKWNADMALGWTPDTDTLLELSVGKGNGESRYGGRGMDGSQFLRESLAARVEKSNIGEVLDKIEAKINYTYVNHIMDNK
TLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLDAGTDMQTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQNKLIS
GARLDRHQVTNYTRAGEPTRSATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGVKSEKT
TQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEMGMEYALTPYWKADASLAYAWGENTR
DNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNSQHRVAINEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLSSGIDN
LLNKAYSEHLNLAGNSGFGYSVNTPLNEPGRTLWAKLNLTF

Specific function: This Protein Is Involved In The Initial Step Of Iron Uptake By Binding Ferrienterobactin (Fe-Ent), An Iron Chelatin Siderophore That Allows E.Coli To Extract Iron From The Environment. Fepa Also Acts As A Receptor For Colicins B And D. [C]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Integral Membrane Protein. Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 74395; Mature: 74395

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGKNKVCKKKLLACAVTSAISAFASNAIADTTSLAAMNRSAINISSTHNSNKKLNDAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCC
VITVTAPLYSPLVVATSPKVPRQPVPASDGADYLRTIPGFSLVRNGGTNGDVVFRGMFGS
EEEEECCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCHHEEECCCCCCCEEEEECCCC
RLKILTDGAEILGTCPSRMDAPTSYISPENFDLLTVVKGPQSVLWGPGASAGTILFERER
EEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCEEEEECCC
PHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNVRVPSQ
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEECCCC
WDKWNADMALGWTPDTDTLLELSVGKGNGESRYGGRGMDGSQFLRESLAARVEKSNIGEV
CCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDKIEAKINYTYVNHIMDNKTLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLDAGTDM
HHHHHHHEEEEEEEHHHCCCCCCCCCCHHHHCCCCHHHHCCEEEEEHHHEEEEECCCCCC
QTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQNKLISGARLDRHQVTNYTRAGEPTR
CCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCC
SATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGVKSEKT
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCHHHCCCCCCCC
TQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEMGMEYA
EEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCEEEEEECCCCCCEE
LTPYWKADASLAYAWGENTRDNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNSQHRVA
ECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHCCCCEEE
INEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLSSGIDNLLNKAYSEHLNLAGNSGFGY
EECCCEECCCCCCCCCCEEEECCEEEEECCEEEECCCHHHHHHHHHHHHCCCCCCCCCCE
SVNTPLNEPGRTLWAKLNLTF
EECCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MISGKNKVCKKKLLACAVTSAISAFASNAIADTTSLAAMNRSAINISSTHNSNKKLNDAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCC
VITVTAPLYSPLVVATSPKVPRQPVPASDGADYLRTIPGFSLVRNGGTNGDVVFRGMFGS
EEEEECCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCHHEEECCCCCCCEEEEECCCC
RLKILTDGAEILGTCPSRMDAPTSYISPENFDLLTVVKGPQSVLWGPGASAGTILFERER
EEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCEEEEECCC
PHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNVRVPSQ
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEECCCC
WDKWNADMALGWTPDTDTLLELSVGKGNGESRYGGRGMDGSQFLRESLAARVEKSNIGEV
CCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDKIEAKINYTYVNHIMDNKTLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLDAGTDM
HHHHHHHEEEEEEEHHHCCCCCCCCCCHHHHCCCCHHHHCCEEEEEHHHEEEEECCCCCC
QTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQNKLISGARLDRHQVTNYTRAGEPTR
CCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCC
SATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGVKSEKT
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCHHHCCCCCCCC
TQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEMGMEYA
EEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCEEEEEECCCCCCEE
LTPYWKADASLAYAWGENTRDNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNSQHRVA
ECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHCCCCEEE
INEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLSSGIDNLLNKAYSEHLNLAGNSGFGY
EECCCEECCCCCCCCCCEEEECCEEEEECCEEEECCCHHHHHHHHHHHHCCCCCCCCCCE
SVNTPLNEPGRTLWAKLNLTF
EECCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA