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The map label for this gene is pabA

Identifier: 51598022

GI number: 51598022

Start: 4427122

End: 4427697

Strand: Reverse

Name: pabA

Synonym: YPTB3732

Alternate gene names: 51598022

Gene position: 4427697-4427122 (Counterclockwise)

Preceding gene: 51598023

Following gene: 51598021

Centisome position: 93.32

GC content: 52.08

Gene sequence:

>576_bases
ATGCTACTGCTGATCGACAACTACGATTCATTTACTTACAACCTGTACCAGTATTTTTGTGAGCTGGGCGCTGAGGTGAT
GGTTAAGCGCAACGATGAGTTGCAACTGACGGATATTGAACAACTGGCCCCCTCACATGTGGTGATCTCTCCCGGCCCTT
GTACCCCTAACGAGGCTGGGATCTCATTGGCGGTTATCCGCCACTTTGCCGATAAACTGCCTATTCTGGGGGTCTGCCTT
GGTCATCAGGCTCTGGGGCAGGCTTTTGGTGCGCGCGTGGTGCGTGCGCGTCAGGTGATGCACGGCAAAACTTCGGCGAT
TTGCCATTCTGGGCAAGGGGTTTTTCGTGGGCTTAATCAGCCATTGACGGTGACCCGTTACCACTCTTTAGTCATTGCCA
CCGACTCCCTACCGGGCTGTTTTGAGCTGACTGCCTGGACGGAGCGGGGCGGTGAGATGGATGAGATTATGGGGATTCGC
CATCGCACATTGCCACTGGAAGGGGTGCAATTCCATCCAGAAAGTATTCTCAGTGAACAGGGCCATCAATTACTGGATAA
TTTTCTTAAAAATTAA

Upstream 100 bases:

>100_bases
TTGGGGTATAGATAATTGGGGTATAGATAAAAATGAATAGTGGGTGTTGGGAATCTATTAAATCATTTATAACTCTAATA
ATCAGTGGGATAAATTAACG

Downstream 100 bases:

>100_bases
TCGGTTGGGCCAATATTATCCCATGACATCATTTATCATTTGCTTGCGGATGATTTTTTATGCATATTTTGTGAGTATAT
TTTCACATGTCAATAAATAA

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MLLLIDNYDSFTYNLYQYFCELGAEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAGISLAVIRHFADKLPILGVCL
GHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQPLTVTRYHSLVIATDSLPGCFELTAWTERGGEMDEIMGIR
HRTLPLEGVQFHPESILSEQGHQLLDNFLKN

Sequences:

>Translated_191_residues
MLLLIDNYDSFTYNLYQYFCELGAEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAGISLAVIRHFADKLPILGVCL
GHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQPLTVTRYHSLVIATDSLPGCFELTAWTERGGEMDEIMGIR
HRTLPLEGVQFHPESILSEQGHQLLDNFLKN
>Mature_191_residues
MLLLIDNYDSFTYNLYQYFCELGAEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAGISLAVIRHFADKLPILGVCL
GHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQPLTVTRYHSLVIATDSLPGCFELTAWTERGGEMDEIMGIR
HRTLPLEGVQFHPESILSEQGHQLLDNFLKN

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=75.1322751322751, Blast_Score=299, Evalue=6e-83,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=42.9319371727749, Blast_Score=143, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=48.6772486772487, Blast_Score=196, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=31.924882629108, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21185; Mature: 21185

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLIDNYDSFTYNLYQYFCELGAEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCHHEEEECCCCEEEECHHHCCCCEEEECCCCCCCCCCC
ISLAVIRHFADKLPILGVCLGHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCHHHHCCCC
PLTVTRYHSLVIATDSLPGCFELTAWTERGGEMDEIMGIRHRTLPLEGVQFHPESILSEQ
CEEEEEEEEEEEEECCCCCEEEEEEHHHCCCCHHHHHCCHHCCCCCCCCEECHHHHHHHH
GHQLLDNFLKN
HHHHHHHHHCC
>Mature Secondary Structure
MLLLIDNYDSFTYNLYQYFCELGAEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCHHEEEECCCCEEEECHHHCCCCEEEECCCCCCCCCCC
ISLAVIRHFADKLPILGVCLGHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCHHHHCCCC
PLTVTRYHSLVIATDSLPGCFELTAWTERGGEMDEIMGIRHRTLPLEGVQFHPESILSEQ
CEEEEEEEEEEEEECCCCCEEEEEEHHHCCCCHHHHHCCHHCCCCCCCCEECHHHHHHHH
GHQLLDNFLKN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]