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The map label for this gene is fadH

Identifier: 51597761

GI number: 51597761

Start: 4130072

End: 4132093

Strand: Direct

Name: fadH

Synonym: YPTB3469

Alternate gene names: 51597761

Gene position: 4130072-4132093 (Clockwise)

Preceding gene: 51597760

Following gene: 51597763

Centisome position: 87.05

GC content: 53.02

Gene sequence:

>2022_bases
ATGTTAGCTTACCCTCACCTGTTCACCCCGCTTGATCTTGGCTTTACCACACTGAAAAATCGTATCTTAATGGGTTCTAT
GCATACTGGGTTGGAGGAGTTACCCGATGGCCCGCAACGTCTGGCGGCATTTTATGCCGAACGCGCAGCAGGCGGTGTCG
GCCTGATTGTGACTGGCGGTATTGCCCCCAATATGAAAGGGGTGGTGTATCAGGGCGCATCGGTACTGAATGACGCCGCG
CAAATCCCCCATCACCAGGTGGTGACAGAGGCGGTTCATCAAGCTGGAGGGAAAATCGCGCTACAAATTCTCCATGCGGG
GCGTTACAGCTACCAGAAACACCCGGTAGCCCCTTCTGCGTTACAAGCGCCTATCAACCCTTTTGTGCCACAAGCATTGA
GCCATGAAGAGATCCTGCAAACTATTGCTGATTTCGCCCACTGTGCGCAATTAGCCAAGCAAGCCGGTTACGACGGTGTC
GAAATCATGGGTTCCGAAGGTTATCTGATCAACCAGTTTCTCACCGCCCGTACTAATCAGCGCGATGATGAATGGGGCGG
TGATTTTACGCACCGAATGCGTTTTGCCGTAGAAATCGTGCGCGCCGTCCGTCAGGCCACGGGACACGACTTTATTCTAA
TTTACCGTTTATCCATGCTTGATCTGGTGGAGGAAGGCTCCAACTGGGTAGAAATCGAGCAATTGGCACAGGCCGTTGAA
CAAGCAGGGGCAACGGTGATCAATACCGGTATCGGCTGGCATGAAGCCCGTATTCCCACCATCGCCACAATGGTGCCACG
GGCCGGATTCAGTTGGGTGACCCGCAAGTTGATGGGGAAAGTGAATATCCCGCTGATCACCACTAACCGAATTAATGACC
CCGCCGTCGCAGAACAAGTGCTGGCCGATGGCTGTGCAGATATGGTGTCAATGGCTCGGCCATTCCTGGCTGATGCCGCT
TTTGTACAAAAAGCGGTACAGGGCCGGGCCGATGAAATTAACACCTGTATTGGTTGTAATCAGGCCTGCCTGGACCAGAT
TTTTGACGGCAAACTGACCTCATGTTTGGTCAATCCCCGTGCTTGCCGCGAAACCGAAATGCCCGAATTACCCACAGACG
CACCAAAACGGTTAGCGGTAGTCGGTGCCGGGCCTGCGGGGTTGGCTTTTGCGGTAACCGCCGCCCGTCGCGGCCATCAG
GTGACATTATTTGATGCTGCCGCAGAGATCGGCGGCCAATTTAATATTGCCAAACAGATCCCCGGCAAAGAGGAATTTTA
CGAAACCCTGCGCTATTTCCGCCGTCAATTAGTGCTGAACGGCGTCACCCTACAATTGAATACCCTGGTGCAGGTAAAGC
AGTTGGCTGAGTTTGATGAAGTGATCCTCGCCTGTGGTATTCAACCACGCTTACCCTGTATCAACGGGATTGATCACCCG
AAAGTACTTACCTATCTGGACGTCTTACGCGATAAAAAACCAGTCGGCCAACGTGTGGCGATTATCGGTGCCGGTGGGAT
TGGTTTTGATACTGCGGAATATCTCAGCCAGTCTGGTGATAGTCCCCGTTTCGATAGCACAGCCTTCAGTACCGAATGGG
GTATTGATCAAGATTTAGCTCATCGGGGGGGCCTATCACCCGCGGGGGCTAAAGTCCCTCCATCCCCACGGCAGATTTTC
CTGTTACAACGTAAAGCCAGCAAAGTCGGTGAAGGGCTGGGTAAAACCACCGGTTGGATCCACCGCACCAGCTTGGCGAT
GCGCGGCGTCAAGATGCTTAACAGCGTCAGCTACGAGGCCATTGATGATAAAGGGTTACATATCATTCGTGCGGAACAAG
CCTGTTGTTTACCTGTCGATACCATTATTATTTGTGCCGGACAGGAGCCACGACGGGAGCTTCATCAGCCCTTACTGGAT
ATGGGAAAAACAGTCTATTTGATTGGTGGTGCAGATAAGGCTGTTGAGCTGGATGCCCGCCGTGCCATTGATCAGGGTAC
CCGCCTAGCGCTAGCCATTTAG

Upstream 100 bases:

>100_bases
TAAATTTGAATAAAAAATCTCATCCGACCACTTGCTGGATTCAGTAAGGGCGGCGGAGATATAACAATAATGGTTGGTTG
TATGCCTGATGGAGACTGCA

Downstream 100 bases:

>100_bases
CCAAGAGAAGAATGGCGCGACCAGCAAGGTAAAGGGCCGTAACAAGGCCGAGAATAGCAATAGAACTGAGAATAATCACA
GGGTGTGGCGAAAACCCCAC

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAGGVGLIVTGGIAPNMKGVVYQGASVLNDAA
QIPHHQVVTEAVHQAGGKIALQILHAGRYSYQKHPVAPSALQAPINPFVPQALSHEEILQTIADFAHCAQLAKQAGYDGV
EIMGSEGYLINQFLTARTNQRDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVEIEQLAQAVE
QAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRINDPAVAEQVLADGCADMVSMARPFLADAA
FVQKAVQGRADEINTCIGCNQACLDQIFDGKLTSCLVNPRACRETEMPELPTDAPKRLAVVGAGPAGLAFAVTAARRGHQ
VTLFDAAAEIGGQFNIAKQIPGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRLPCINGIDHP
KVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFSTEWGIDQDLAHRGGLSPAGAKVPPSPRQIF
LLQRKASKVGEGLGKTTGWIHRTSLAMRGVKMLNSVSYEAIDDKGLHIIRAEQACCLPVDTIIICAGQEPRRELHQPLLD
MGKTVYLIGGADKAVELDARRAIDQGTRLALAI

Sequences:

>Translated_673_residues
MLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAGGVGLIVTGGIAPNMKGVVYQGASVLNDAA
QIPHHQVVTEAVHQAGGKIALQILHAGRYSYQKHPVAPSALQAPINPFVPQALSHEEILQTIADFAHCAQLAKQAGYDGV
EIMGSEGYLINQFLTARTNQRDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVEIEQLAQAVE
QAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRINDPAVAEQVLADGCADMVSMARPFLADAA
FVQKAVQGRADEINTCIGCNQACLDQIFDGKLTSCLVNPRACRETEMPELPTDAPKRLAVVGAGPAGLAFAVTAARRGHQ
VTLFDAAAEIGGQFNIAKQIPGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRLPCINGIDHP
KVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFSTEWGIDQDLAHRGGLSPAGAKVPPSPRQIF
LLQRKASKVGEGLGKTTGWIHRTSLAMRGVKMLNSVSYEAIDDKGLHIIRAEQACCLPVDTIIICAGQEPRRELHQPLLD
MGKTVYLIGGADKAVELDARRAIDQGTRLALAI
>Mature_673_residues
MLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAGGVGLIVTGGIAPNMKGVVYQGASVLNDAA
QIPHHQVVTEAVHQAGGKIALQILHAGRYSYQKHPVAPSALQAPINPFVPQALSHEEILQTIADFAHCAQLAKQAGYDGV
EIMGSEGYLINQFLTARTNQRDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVEIEQLAQAVE
QAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRINDPAVAEQVLADGCADMVSMARPFLADAA
FVQKAVQGRADEINTCIGCNQACLDQIFDGKLTSCLVNPRACRETEMPELPTDAPKRLAVVGAGPAGLAFAVTAARRGHQ
VTLFDAAAEIGGQFNIAKQIPGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRLPCINGIDHP
KVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFSTEWGIDQDLAHRGGLSPAGAKVPPSPRQIF
LLQRKASKVGEGLGKTTGWIHRTSLAMRGVKMLNSVSYEAIDDKGLHIIRAEQACCLPVDTIIICAGQEPRRELHQPLLD
MGKTVYLIGGADKAVELDARRAIDQGTRLALAI

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=672, Percent_Identity=72.7678571428571, Blast_Score=1012, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=342, Percent_Identity=30.1169590643275, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17559804, Length=357, Percent_Identity=23.249299719888, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=327, Percent_Identity=23.2415902140673, Blast_Score=83, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=343, Percent_Identity=23.0320699708455, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17565138, Length=239, Percent_Identity=24.6861924686192, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540738, Length=220, Percent_Identity=23.1818181818182, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17566914, Length=214, Percent_Identity=29.9065420560748, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI72001454, Length=230, Percent_Identity=23.9130434782609, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321973, Length=224, Percent_Identity=29.9107142857143, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=227, Percent_Identity=29.5154185022026, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 72975; Mature: 72975

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAGGVGLIVTGG
CCCCCCCCCCHHCCHHHHHHHHEECHHHHCHHHCCCCHHHHHHHHHHHHCCCEEEEEECC
IAPNMKGVVYQGASVLNDAAQIPHHQVVTEAVHQAGGKIALQILHAGRYSYQKHPVAPSA
CCCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHH
LQAPINPFVPQALSHEEILQTIADFAHCAQLAKQAGYDGVEIMGSEGYLINQFLTARTNQ
HHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCC
RDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVEIEQLAQAVE
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEHHHHHHHHHH
QAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRINDPAVAEQV
HCCCEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
LADGCADMVSMARPFLADAAFVQKAVQGRADEINTCIGCNQACLDQIFDGKLTSCLVNPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCHHHHHCCCH
ACRETEMPELPTDAPKRLAVVGAGPAGLAFAVTAARRGHQVTLFDAAAEIGGQFNIAKQI
HHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHCCCEEEHHCC
PGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRLPCINGIDHP
CCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
KVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFSTEWGIDQDLA
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
HRGGLSPAGAKVPPSPRQIFLLQRKASKVGEGLGKTTGWIHRTSLAMRGVKMLNSVSYEA
HHCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHH
IDDKGLHIIRAEQACCLPVDTIIICAGQEPRRELHQPLLDMGKTVYLIGGADKAVELDAR
CCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCEEHHHH
RAIDQGTRLALAI
HHHCCCCEEEEEC
>Mature Secondary Structure
MLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAGGVGLIVTGG
CCCCCCCCCCHHCCHHHHHHHHEECHHHHCHHHCCCCHHHHHHHHHHHHCCCEEEEEECC
IAPNMKGVVYQGASVLNDAAQIPHHQVVTEAVHQAGGKIALQILHAGRYSYQKHPVAPSA
CCCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHH
LQAPINPFVPQALSHEEILQTIADFAHCAQLAKQAGYDGVEIMGSEGYLINQFLTARTNQ
HHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCC
RDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVEIEQLAQAVE
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEHHHHHHHHHH
QAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRINDPAVAEQV
HCCCEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
LADGCADMVSMARPFLADAAFVQKAVQGRADEINTCIGCNQACLDQIFDGKLTSCLVNPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCHHHHHCCCH
ACRETEMPELPTDAPKRLAVVGAGPAGLAFAVTAARRGHQVTLFDAAAEIGGQFNIAKQI
HHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHCCCEEEHHCC
PGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRLPCINGIDHP
CCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
KVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFSTEWGIDQDLA
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
HRGGLSPAGAKVPPSPRQIFLLQRKASKVGEGLGKTTGWIHRTSLAMRGVKMLNSVSYEA
HHCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHH
IDDKGLHIIRAEQACCLPVDTIIICAGQEPRRELHQPLLDMGKTVYLIGGADKAVELDAR
CCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCEEHHHH
RAIDQGTRLALAI
HHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]