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The map label for this gene is pepT [C]

Identifier: 51597599

GI number: 51597599

Start: 3917202

End: 3918434

Strand: Reverse

Name: pepT [C]

Synonym: YPTB3299

Alternate gene names: 51597599

Gene position: 3918434-3917202 (Counterclockwise)

Preceding gene: 51597600

Following gene: 51597598

Centisome position: 82.59

GC content: 49.8

Gene sequence:

>1233_bases
ATGACTATCGCACTCTCAGAACAACTGACAAACCGCTTTTTCCGTTATCTGGCGGTTAGCAGCCAGAGCGATGCCGCCTC
ACCAACACTGCCGAGTACCGAAGGGCAGCACAAAATGGCGCAGATGTTAGCTGAAGAACTGCGTCAATTGGGGTTGGAAG
ATATCCTGATTGATGAACATGCCACGGTGACAGCCCGTAAACCCGGCAATCAGCCTACCGCACCACGCATTGGTTTTATT
ACACATATTGATACGGTCGACGTTGGCTTATCGCCCGATATTCATCCGCAACGCTTACGCTTTACCGGTAGCGATCTTTG
CCTAAACGCAGAGCAGGGCATCTATCTACGTACCGCAGAACATCCGGAAATCCTGCGTTATCAGGGCGAAGAGATTATTT
TCAGCGATGGCACCAGTGTACTAGGCGCAGATAATAAAGCGGCAGTGACCGTAGTCATGACGTTGTTGGAAAACCTGACG
GCTGACGATTGCCATGGCGATATCGTGGTGGCGTTTGTTCCTGACGAAGAGATTGGTCTGCGCGGTGCCAAAGCGCTGGA
TCTGGCGCGTTTTGATGTTGATTTCGCTTACACTATTGACTGCTGCGAGCTGGGCGAAGTGGTGTATGAAAACTTTAACG
CCGCCTCGGCAGAGATCGACATCATCGGGGTGACGGCTCACCCGATGTCAGCTAAAAATGTGCTGATCAACCCTATCCGT
GTCGCCTATGACATTATCAGTGAGTTCTCGCCACAAGAGACGCCAGAACACACTGAAGGGCGGGAAGGCTATGTCTGGTT
TACCGATATGACTGCCAACCCTAACAGCGCAAAACTGAAAATAGCAATCCGTGATTTTGATAATGTGTCATTCGCCGCGC
GTAAAGCCTATATCGGTGAAGTGGTCGCGAAAGTTTCAGCACAATATCCCCGAGCGAAGATCAGCTACTCCGTGACCGAT
GTGTACAGCAATATCAGTAACTCGATTGGTGAAGATAAGCGGGCTATCGACCTGATCTTCTCTTCTATGGCGGAACTGAA
TATCGAACCTAAAGTGATCCCTATGCGCGGCGGTACCGATGGTGCGGCATTATCAACCCAAGGGTTGCTGACTCCAAATT
ATTTTACCGGGGCGCATAATTTCCACTCACCTTTCGAATTTTTACCGATCAGCTCCTTTGTGAAATCATATCAATTAACC
CGGACGATCTGTTTGTCTGCGGCCAAAGTGTAA

Upstream 100 bases:

>100_bases
TGCTGCAACGCCAATGACTTTGGGGGGCTTCGGCCTTGACGCTGTAGGGGCATTAGCTGCGCGCACTCAGTGGTTTTAGC
TATAAATAAAGGAATAAAAA

Downstream 100 bases:

>100_bases
AAGCTGGAAAGGCATTGATATTAAATGCCTTATCTCCATGCAGGGTACTGGTGTGTTAACTTGCCAGTACCCTAAATACT
GTGACTTCTGCTGTACGCCT

Product: peptidase T

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTIALSEQLTNRFFRYLAVSSQSDAASPTLPSTEGQHKMAQMLAEELRQLGLEDILIDEHATVTARKPGNQPTAPRIGFI
THIDTVDVGLSPDIHPQRLRFTGSDLCLNAEQGIYLRTAEHPEILRYQGEEIIFSDGTSVLGADNKAAVTVVMTLLENLT
ADDCHGDIVVAFVPDEEIGLRGAKALDLARFDVDFAYTIDCCELGEVVYENFNAASAEIDIIGVTAHPMSAKNVLINPIR
VAYDIISEFSPQETPEHTEGREGYVWFTDMTANPNSAKLKIAIRDFDNVSFAARKAYIGEVVAKVSAQYPRAKISYSVTD
VYSNISNSIGEDKRAIDLIFSSMAELNIEPKVIPMRGGTDGAALSTQGLLTPNYFTGAHNFHSPFEFLPISSFVKSYQLT
RTICLSAAKV

Sequences:

>Translated_410_residues
MTIALSEQLTNRFFRYLAVSSQSDAASPTLPSTEGQHKMAQMLAEELRQLGLEDILIDEHATVTARKPGNQPTAPRIGFI
THIDTVDVGLSPDIHPQRLRFTGSDLCLNAEQGIYLRTAEHPEILRYQGEEIIFSDGTSVLGADNKAAVTVVMTLLENLT
ADDCHGDIVVAFVPDEEIGLRGAKALDLARFDVDFAYTIDCCELGEVVYENFNAASAEIDIIGVTAHPMSAKNVLINPIR
VAYDIISEFSPQETPEHTEGREGYVWFTDMTANPNSAKLKIAIRDFDNVSFAARKAYIGEVVAKVSAQYPRAKISYSVTD
VYSNISNSIGEDKRAIDLIFSSMAELNIEPKVIPMRGGTDGAALSTQGLLTPNYFTGAHNFHSPFEFLPISSFVKSYQLT
RTICLSAAKV
>Mature_409_residues
TIALSEQLTNRFFRYLAVSSQSDAASPTLPSTEGQHKMAQMLAEELRQLGLEDILIDEHATVTARKPGNQPTAPRIGFIT
HIDTVDVGLSPDIHPQRLRFTGSDLCLNAEQGIYLRTAEHPEILRYQGEEIIFSDGTSVLGADNKAAVTVVMTLLENLTA
DDCHGDIVVAFVPDEEIGLRGAKALDLARFDVDFAYTIDCCELGEVVYENFNAASAEIDIIGVTAHPMSAKNVLINPIRV
AYDIISEFSPQETPEHTEGREGYVWFTDMTANPNSAKLKIAIRDFDNVSFAARKAYIGEVVAKVSAQYPRAKISYSVTDV
YSNISNSIGEDKRAIDLIFSSMAELNIEPKVIPMRGGTDGAALSTQGLLTPNYFTGAHNFHSPFEFLPISSFVKSYQLTR
TICLSAAKV

Specific function: Releases The N-Terminal Amino Acid From Tripeptides. Has A Preference For Tripeptides Containing A N-Terminal Methionine Or Leucine (By Similarity). [C]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family [H]

Homologues:

Organism=Escherichia coli, GI1787372, Length=408, Percent_Identity=38.2352941176471, Blast_Score=279, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.4.11.4 [C]

Molecular weight: Translated: 44919; Mature: 44788

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIALSEQLTNRFFRYLAVSSQSDAASPTLPSTEGQHKMAQMLAEELRQLGLEDILIDEH
CEEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEECCC
ATVTARKPGNQPTAPRIGFITHIDTVDVGLSPDIHPQRLRFTGSDLCLNAEQGIYLRTAE
CEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHEEECCCCEEEECCCCEEEEECC
HPEILRYQGEEIIFSDGTSVLGADNKAAVTVVMTLLENLTADDCHGDIVVAFVPDEEIGL
CCHHHHCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCC
RGAKALDLARFDVDFAYTIDCCELGEVVYENFNAASAEIDIIGVTAHPMSAKNVLINPIR
CCCCEEEEEEECCEEEEEECHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEECHHH
VAYDIISEFSPQETPEHTEGREGYVWFTDMTANPNSAKLKIAIRDFDNVSFAARKAYIGE
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHH
VVAKVSAQYPRAKISYSVTDVYSNISNSIGEDKRAIDLIFSSMAELNIEPKVIPMRGGTD
HHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCC
GAALSTQGLLTPNYFTGAHNFHSPFEFLPISSFVKSYQLTRTICLSAAKV
CCCEECCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIALSEQLTNRFFRYLAVSSQSDAASPTLPSTEGQHKMAQMLAEELRQLGLEDILIDEH
EEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEECCC
ATVTARKPGNQPTAPRIGFITHIDTVDVGLSPDIHPQRLRFTGSDLCLNAEQGIYLRTAE
CEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHEEECCCCEEEECCCCEEEEECC
HPEILRYQGEEIIFSDGTSVLGADNKAAVTVVMTLLENLTADDCHGDIVVAFVPDEEIGL
CCHHHHCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCC
RGAKALDLARFDVDFAYTIDCCELGEVVYENFNAASAEIDIIGVTAHPMSAKNVLINPIR
CCCCEEEEEEECCEEEEEECHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEECHHH
VAYDIISEFSPQETPEHTEGREGYVWFTDMTANPNSAKLKIAIRDFDNVSFAARKAYIGE
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHH
VVAKVSAQYPRAKISYSVTDVYSNISNSIGEDKRAIDLIFSSMAELNIEPKVIPMRGGTD
HHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCC
GAALSTQGLLTPNYFTGAHNFHSPFEFLPISSFVKSYQLTRTICLSAAKV
CCCEECCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Aminopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]