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The map label for this gene is iucC

Identifier: 51597567

GI number: 51597567

Start: 3846315

End: 3848063

Strand: Direct

Name: iucC

Synonym: YPTB3265

Alternate gene names: 51597567

Gene position: 3846315-3848063 (Clockwise)

Preceding gene: 51597566

Following gene: 51597568

Centisome position: 81.07

GC content: 53.97

Gene sequence:

>1749_bases
ATGATCACCACCGATTACGCTAACTGGCAGCAGGTTAATCGCCACATGATCGCTAAAATCCTTAGCGAACTGGAATATGA
ACGCACTCTGCATGCTGAATTACACGGTGAAACAGGGCGCATCACCTTGCCCGGCGCGGTTTACACCTTTAACGGCAAGC
GGGGTATCTGGGGTTGGCTACATATTGATCCTGCCACGCTGCGCTGTGAGGGTGTGCCGCTCGCCGCTGACCACATGCTG
CGCCAACTGGCGCTCGTGCTGAAGATGGACGATTCGCAGGTCGCAGAGCACCTTGAAGATTTGTACGCCACACTGCGTGG
AGACATGCAATTACTCTCCGCTCGCCACGGTATGAGTGCGGAAGCGTTGATCGCCCTTAATGATGATGCCCTGCAATGCC
TGCTGGCCGGTCACCCGAAATTTATCTTCAACAAAGGCCGCCGCGGCTGGGGCTTAACCGCCCTGCAACACTATGCGCCC
GAATATCAGGGCCAATTTCGTCTGCATTGGGTCGCAGCCAAACGCGGCAGCTTTATTTGGTGCGTGGATGCCGAATACCC
GTTGGACAACTTGCTCAACAGCGCCATGGACCCCGCCGAACGCCAACGCTTTGATCGCCGCTGGCGTGAGTGCCAATTGA
ATGATGATTGGGTCCCGGTGCCTTTACATCCGTGGCAATGGCAGCAAAAAATTGCCTTGCACTTCCTGCCACAACTTGCC
GAGGGTGAACTGATCGAACTGGGTGAATTTGGCGATCACTATCTGGCGCAACAATCGTTACGCACATTAACCAATGTCAG
CCGCCGTGTGCCATTTGATATCAAACTGCCACTCACCATTTACAACACCTCTTGTTATCGTGGCATCCCAGGCAAATACA
TCAGCGCAGGCCCCGCGGCTTCGCGCTGGTTGCAGCAAGTCTTCGCACAAGACCGCACACTGCATGAAAGCGGGGCTGAG
ATCCTCGGTGAACCCGCCGCAGGTTATATGCTGCACCAGACCTACGCCACACTTGCCAAGGCGCCTTATCGCTGCCAGGA
AATGCTCGGTGTGATTTGGCGAGAGAATCCGTCCTGCTATTTGCGAGAGGGTGAACATGCCATTTTGATGGCGACGCTGA
TGGAAACCAACAATCAGGGTCATCCGCTGATCGCGGCCTATATTGCACGTTCGGGGTTAAGTGCTGAAGCCTGGCTGGAG
CAGATGTTCCGTGTGGTAGTGGTGCCGATGTACCACCTGATGTGTTGCTACGGCGTGGCGCTAATTGCCCACGGCCAGAA
CATCACTCTGGTAATGAAAGACCATGCCCCCCAGCGCATCCTATTGAAAGATTTCCAGGGCGATATGCGTCTGGTCGATA
AAGATTTTCCGCAAGCGGCCTCGCTGCCTAACGTGGTTAAAGAGGTGACTGTGCGCTTATCTGCCGACTACCTCATCCAC
GATCTGCAAACCGGCCATTTTGTCACCGTATTACGCTTTATTTCACCGTTGATGCAGGCTTGCAACCTGAGCGAATACCG
CTTCTATCAACTGCTGGCACAGGTGCTGGAGCGCTACATGGCGCAGCATCCAGATTTGGCAGACCGCTTTACCTTATTCA
ATTTATTTAAACCACAGATTATCCGTGTGGTCCTCAACCCAGTAAAACTCACCTACTCAGAGCAGGACGGCGGCAGCCGC
ATGTTGCCTGATTATTTGCAGGATCTGGATAACCCCCTTTATTTGGTCACCAAGGAGCTAGCCCAATGA

Upstream 100 bases:

>100_bases
CCGCCGCTGGCTACCACACCTTAAAAGAGTTTGATTTCCCGCATAAACGTTCGCGTCTGATTATGAATCAACGCGCCGAT
TTCTTCCGGGAGGGTACACG

Downstream 100 bases:

>100_bases
ATCAGCCTCTGGATTTCATCGGCATTGGCATCGGCCCATTTAACCTCAGTATTGCCGCACTTGGCAGTGAAGTTTCTGGC
TTTAACAGTAAATTTCTCGA

Product: siderophore biosynthesis protein IucC

Products: ADP; phosphate; aerobactin

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MITTDYANWQQVNRHMIAKILSELEYERTLHAELHGETGRITLPGAVYTFNGKRGIWGWLHIDPATLRCEGVPLAADHML
RQLALVLKMDDSQVAEHLEDLYATLRGDMQLLSARHGMSAEALIALNDDALQCLLAGHPKFIFNKGRRGWGLTALQHYAP
EYQGQFRLHWVAAKRGSFIWCVDAEYPLDNLLNSAMDPAERQRFDRRWRECQLNDDWVPVPLHPWQWQQKIALHFLPQLA
EGELIELGEFGDHYLAQQSLRTLTNVSRRVPFDIKLPLTIYNTSCYRGIPGKYISAGPAASRWLQQVFAQDRTLHESGAE
ILGEPAAGYMLHQTYATLAKAPYRCQEMLGVIWRENPSCYLREGEHAILMATLMETNNQGHPLIAAYIARSGLSAEAWLE
QMFRVVVVPMYHLMCCYGVALIAHGQNITLVMKDHAPQRILLKDFQGDMRLVDKDFPQAASLPNVVKEVTVRLSADYLIH
DLQTGHFVTVLRFISPLMQACNLSEYRFYQLLAQVLERYMAQHPDLADRFTLFNLFKPQIIRVVLNPVKLTYSEQDGGSR
MLPDYLQDLDNPLYLVTKELAQ

Sequences:

>Translated_582_residues
MITTDYANWQQVNRHMIAKILSELEYERTLHAELHGETGRITLPGAVYTFNGKRGIWGWLHIDPATLRCEGVPLAADHML
RQLALVLKMDDSQVAEHLEDLYATLRGDMQLLSARHGMSAEALIALNDDALQCLLAGHPKFIFNKGRRGWGLTALQHYAP
EYQGQFRLHWVAAKRGSFIWCVDAEYPLDNLLNSAMDPAERQRFDRRWRECQLNDDWVPVPLHPWQWQQKIALHFLPQLA
EGELIELGEFGDHYLAQQSLRTLTNVSRRVPFDIKLPLTIYNTSCYRGIPGKYISAGPAASRWLQQVFAQDRTLHESGAE
ILGEPAAGYMLHQTYATLAKAPYRCQEMLGVIWRENPSCYLREGEHAILMATLMETNNQGHPLIAAYIARSGLSAEAWLE
QMFRVVVVPMYHLMCCYGVALIAHGQNITLVMKDHAPQRILLKDFQGDMRLVDKDFPQAASLPNVVKEVTVRLSADYLIH
DLQTGHFVTVLRFISPLMQACNLSEYRFYQLLAQVLERYMAQHPDLADRFTLFNLFKPQIIRVVLNPVKLTYSEQDGGSR
MLPDYLQDLDNPLYLVTKELAQ
>Mature_582_residues
MITTDYANWQQVNRHMIAKILSELEYERTLHAELHGETGRITLPGAVYTFNGKRGIWGWLHIDPATLRCEGVPLAADHML
RQLALVLKMDDSQVAEHLEDLYATLRGDMQLLSARHGMSAEALIALNDDALQCLLAGHPKFIFNKGRRGWGLTALQHYAP
EYQGQFRLHWVAAKRGSFIWCVDAEYPLDNLLNSAMDPAERQRFDRRWRECQLNDDWVPVPLHPWQWQQKIALHFLPQLA
EGELIELGEFGDHYLAQQSLRTLTNVSRRVPFDIKLPLTIYNTSCYRGIPGKYISAGPAASRWLQQVFAQDRTLHESGAE
ILGEPAAGYMLHQTYATLAKAPYRCQEMLGVIWRENPSCYLREGEHAILMATLMETNNQGHPLIAAYIARSGLSAEAWLE
QMFRVVVVPMYHLMCCYGVALIAHGQNITLVMKDHAPQRILLKDFQGDMRLVDKDFPQAASLPNVVKEVTVRLSADYLIH
DLQTGHFVTVLRFISPLMQACNLSEYRFYQLLAQVLERYMAQHPDLADRFTLFNLFKPQIIRVVLNPVKLTYSEQDGGSR
MLPDYLQDLDNPLYLVTKELAQ

Specific function: Unknown

COG id: COG4264

COG function: function code Q; Siderophore synthetase component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iucC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007310
- InterPro:   IPR022770 [H]

Pfam domain/function: PF06276 FhuF; PF04183 IucA_IucC [H]

EC number: 6.3.2.27

Molecular weight: Translated: 66579; Mature: 66579

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTDYANWQQVNRHMIAKILSELEYERTLHAELHGETGRITLPGAVYTFNGKRGIWGWL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCEEEEE
HIDPATLRCEGVPLAADHMLRQLALVLKMDDSQVAEHLEDLYATLRGDMQLLSARHGMSA
EECCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EALIALNDDALQCLLAGHPKFIFNKGRRGWGLTALQHYAPEYQGQFRLHWVAAKRGSFIW
CEEEEECHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCEEE
CVDAEYPLDNLLNSAMDPAERQRFDRRWRECQLNDDWVPVPLHPWQWQQKIALHFLPQLA
EEECCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHC
EGELIELGEFGDHYLAQQSLRTLTNVSRRVPFDIKLPLTIYNTSCYRGIPGKYISAGPAA
CCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHH
SRWLQQVFAQDRTLHESGAEILGEPAAGYMLHQTYATLAKAPYRCQEMLGVIWRENPSCY
HHHHHHHHHHCCHHHHCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEE
LREGEHAILMATLMETNNQGHPLIAAYIARSGLSAEAWLEQMFRVVVVPMYHLMCCYGVA
EECCCCEEEEEEEHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAHGQNITLVMKDHAPQRILLKDFQGDMRLVDKDFPQAASLPNVVKEVTVRLSADYLIH
HHCCCCCEEEEECCCCCCCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DLQTGHFVTVLRFISPLMQACNLSEYRFYQLLAQVLERYMAQHPDLADRFTLFNLFKPQI
HCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IRVVLNPVKLTYSEQDGGSRMLPDYLQDLDNPLYLVTKELAQ
HHHHHCCCEEEEECCCCCCCCCHHHHHHCCCCCEEHHHHHCC
>Mature Secondary Structure
MITTDYANWQQVNRHMIAKILSELEYERTLHAELHGETGRITLPGAVYTFNGKRGIWGWL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCEEEEE
HIDPATLRCEGVPLAADHMLRQLALVLKMDDSQVAEHLEDLYATLRGDMQLLSARHGMSA
EECCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EALIALNDDALQCLLAGHPKFIFNKGRRGWGLTALQHYAPEYQGQFRLHWVAAKRGSFIW
CEEEEECHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCEEE
CVDAEYPLDNLLNSAMDPAERQRFDRRWRECQLNDDWVPVPLHPWQWQQKIALHFLPQLA
EEECCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHC
EGELIELGEFGDHYLAQQSLRTLTNVSRRVPFDIKLPLTIYNTSCYRGIPGKYISAGPAA
CCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHH
SRWLQQVFAQDRTLHESGAEILGEPAAGYMLHQTYATLAKAPYRCQEMLGVIWRENPSCY
HHHHHHHHHHCCHHHHCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEE
LREGEHAILMATLMETNNQGHPLIAAYIARSGLSAEAWLEQMFRVVVVPMYHLMCCYGVA
EECCCCEEEEEEEHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAHGQNITLVMKDHAPQRILLKDFQGDMRLVDKDFPQAASLPNVVKEVTVRLSADYLIH
HHCCCCCEEEEECCCCCCCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DLQTGHFVTVLRFISPLMQACNLSEYRFYQLLAQVLERYMAQHPDLADRFTLFNLFKPQI
HCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IRVVLNPVKLTYSEQDGGSRMLPDYLQDLDNPLYLVTKELAQ
HHHHHCCCEEEEECCCCCCCCCHHHHHHCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; citrate; N6-acetyl-N6-hydroxylysine

Specific reaction: 4 ATP + citrate + N6-acetyl-N6-hydroxylysine = 4 ADP + 4 phosphate + aerobactin

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8003107 [H]