Click here to switch to the map view.

The map label for this gene is clpB3

Identifier: 51597550

GI number: 51597550

Start: 3823069

End: 3825717

Strand: Reverse

Name: clpB3

Synonym: YPTB3246

Alternate gene names: 51597550

Gene position: 3825717-3823069 (Counterclockwise)

Preceding gene: 51597551

Following gene: 51597549

Centisome position: 80.63

GC content: 59.23

Gene sequence:

>2649_bases
ATGACAACGCATTCAGCACACTTATTACGCCGCTTAAATCCCTATTGCGCACAGGCACTGGCCGGTGCTGCCACCCTGTG
TCAGACCCGCGCCCATGCCGAGATCACTGTCGAACACTGGTTGTTAAAACTGCTGGAGCAGGGCGAAGGCGATATCACGG
TGATTGCCCGGCGTTATGAGTGGGACATGGACAGCCTGTGGCAGGGATTACTGTCCCATCTGGACACCTTGCCGCGCACG
GTACAGGGCAAACCTCAGTTGTCCGCCGCGTTACAGCAACTGATCAAAAGTGCCTGGCTGGATGCCTCGTTGCAGGAAAA
TGCTGATGCGGTGCGCTCGGTTCATCTAATGGCAGCGCTGATAAATTCGCCATCATTATTGGCCGCCGATGCCGCCTGGC
CGTTGCTCAGCCTGAGCACTACCCAACTACACCGCTTGTTGCCGTTGCTGGACAGCCAATCCGACGAACGTCCTGAGGTG
CAGCAGGCTGCGGCACTGGCCGACAGCCCGGTCAATCTGGCCGATGAGGCCGCGACGGTTACCTCCGCCAGTGGTCAGCC
GCAACTGAATGACGCGCTGCAAGCGGCGCTGGATAAATTTACCCTCGATGTCACCGCTAAAGCCCGTGCCAACCAGATTG
ATCCGATTTTTGGCCGCGACAGCGAAATCCGCCAGATGATCGATATCCTGTCGCGCCGCCGTAAAAACAACCCGATTCTG
GTCGGTGAACCGGGCGTCGGTAAAACCGCGCTGGTTGAAGGGCTGGCGCTACGTATTGCCGACGGCAACGTACCGGACAG
CCTGAAAACCGTCAGTGTGCGCACACTGGATTTGGGTCTGTTACAGGCCGGGGCTGGGGTCAAAGGCGAATTCGAACAGC
GCCTGAAAAATGTTATCGAGGCGGTACAACAATCCCCCAGCCCGGTGCTGCTGTTTATCGACGAAGCCCACACCATTATC
GGGGCCGGTAATCAGGCCGGTGGTGCCGATGCGGCTAACCTGCTGAAACCGGCACTGGCGCGTGGCGAACTGCGCACCAT
CGCCGCCACCACCTGGTCCGAATACAAACAGTATTTTGAACGCGATGCCGCACTGGAGCGCCGCTTCCAGATGGTCAAAG
TGGACGAGCCGGATGATGACACCGCCTGCCTGATGCTGCGTGGCCTGAAAGAACGTTACGCCACCCATCACGGCGTGCAT
ATTCTGGACGCCGCTATCACCGCAGCGGTTACCCTGTCGCGCCGCTTCCTGACCGGCCGCCAACTGCCGGACAAAGCGGT
GGATCTGCTCGATACCGCCGGTGCCCGGGTGCGCATGAGCATTGACACCTTGCCGACTGCGCTGATGGCGATTAACGCCG
AGCTGGCCGCACTGGCGATGGAGCAACAGGCCATCGAACAGGACTTGCTCCTGCTGCCGAATGTCAGTTCAACGCGCTTA
CCTGAGATTGAGCAACGCCGCGCCGCGCTGGCGGTTGGGCAGCACACACTCGAACAGCAATATAAAGAAGAAAAACGGCT
GACCACCCTGATTATCGAGGCGCGTCAGGATATCGCCAACGTGGCACATCTGGTCGCGTTGCAGGAGGAACTCGTTCAGA
TCCAAGGCAACGCGCCGCTGCTGTCGCTGGACGTTGATGTGCGCACTGTTGCGGCTGTGATCGCCGACTGGACCGGTGTG
CCGCTGGGCAGTTTACTCAAAGACGAACAAACCAACTTGCTGTCACTGGAAAATCGTCTGGGCGAGCGAGTAATTGGGCA
GGATGCGGCATTAGGCGCGCTGGCGCAACGGCTGCGGGCGGCGAAAACCGGCCTGACATCAGAGAATGGTCCGCTGGGGG
TGTTCCTGCTGGTCGGGCCGAGTGGGATCGGCAAAACCGAAACCGCGCTGGCACTGGCCGACAGCCTGTTCGGCGGCGAG
AAATCGCTGATCACCATCAACTTATCGGAGTATCAGGAAGCACACACCGTCTCCCAATTGAAAGGGTCGCCACCGGGCTA
TGTCGGTTACGGACAGGGCGGCGTATTGACCGAAGCGGTGCGCAAACGGCCTTACAGCGTGGTGCTGCTGGATGAAGTCG
AGAAGGCCCATCGTGATGTGCTGAACCTGTTCTATCAGGTGTTTGACCGCGGTTTTATGCGCGACGGTGAAGGGCGCGAA
ATTGATTTCCGCAACACGGTGATGGTGATGACCGCCAATCTGGGCAGTGATCATCTGATGCAGTTGCTCGATGAGCAACC
GGACGCGCCGGACAGCACCCTGCATGAACTGCTGCGGCCAATATTGCGCGACCACTTCCAGCCCGCGCTGCTGGCCCGCT
TCCAGACGCTGATCTACCGCCCACTGAATGCCCCCGCGCTGCGCACCATCGTCGAAATGAAACTGGCACAGGTCGCTAAC
CGCCTCAAAAAACATTACGGCCTGCACTGCACTCTTGAAGCAAGCCTGTACGACACACTGGTCGCCGCCTGCCTGCTGCC
GGACACCGGCGCACGCAACATCGACAGCCTGCTCAATCAGCAGATTTTACCGGTATTGAGCCAGCAGCTGTTAAGCCGCA
TGAGCGAGCAACAGCGCACCACCTCGCTGACGCTGGGCTGGGATGAAGCCGACGGCATTACCCTTGAATTTGAAGGAGGC
GAAAAATGA

Upstream 100 bases:

>100_bases
TGTGCGCTGTCCGTGTGCAAACTGACTGCGACAATAACGCCAACTGAAACCGGCTTACTTATCCGGTATCGCAAAGGTTT
CGCAAACAAGGAAGATCTTA

Downstream 100 bases:

>100_bases
ATACCACTCTCCCGACTCTTCGGTTTGACCATAGCCACCACAAACTGGTGGTCCGCGACAGCACCGCCGCCGTTGATGTG
TTGGGCTTTGAAGGCCACGA

Product: Clp ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 882; Mature: 881

Protein sequence:

>882_residues
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLSHLDTLPRT
VQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAALINSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEV
QQAAALADSPVNLADEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVH
ILDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGV
PLGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGE
KSLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
IDFRNTVMVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRPLNAPALRTIVEMKLAQVAN
RLKKHYGLHCTLEASLYDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGG
EK

Sequences:

>Translated_882_residues
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLSHLDTLPRT
VQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAALINSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEV
QQAAALADSPVNLADEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVH
ILDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGV
PLGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGE
KSLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
IDFRNTVMVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRPLNAPALRTIVEMKLAQVAN
RLKKHYGLHCTLEASLYDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGG
EK
>Mature_881_residues
TTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLSHLDTLPRTV
QGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAALINSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEVQ
QAAALADSPVNLADEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPILV
GEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTIIG
AGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHI
LDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRLP
EIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGVP
LGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEK
SLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGREI
DFRNTVMVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRPLNAPALRTIVEMKLAQVANR
LKKHYGLHCTLEASLYDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGGE
K

Specific function: Required for secretion of hcp1 probably by providing the energy source for its translocation [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=301, Percent_Identity=34.21926910299, Blast_Score=166, Evalue=9e-41,
Organism=Escherichia coli, GI1788943, Length=684, Percent_Identity=43.7134502923977, Blast_Score=553, Evalue=1e-158,
Organism=Escherichia coli, GI1787109, Length=270, Percent_Identity=44.8148148148148, Blast_Score=242, Evalue=8e-65,
Organism=Saccharomyces cerevisiae, GI6320464, Length=764, Percent_Identity=39.7905759162304, Blast_Score=475, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6323002, Length=707, Percent_Identity=37.6237623762376, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96273; Mature: 96142

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYE
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEEEECC
WDMDSLWQGLLSHLDTLPRTVQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAAL
CCHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
INSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEVQQAAALADSPVNLADEAATV
HCCCCEEECCCCCCHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHH
TSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
CCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIE
EECCCCCHHHHHHHHEEEEECCCCCCCHHEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHH
AVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFE
HHHCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHILDAAITAAVTLSRRFLTGR
HHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
QLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
CCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCC
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LSLDVDVRTVAAVIADWTGVPLGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRA
EEECCHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEKSLITINLSEYQEAHTVSQL
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHH
KGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
CCCCCCEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
IDFRNTVMVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYR
EECCCEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PLNAPALRTIVEMKLAQVANRLKKHYGLHCTLEASLYDTLVAACLLPDTGARNIDSLLNQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHH
QILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGGEK
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCC
>Mature Secondary Structure 
TTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYE
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEEEECC
WDMDSLWQGLLSHLDTLPRTVQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAAL
CCHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
INSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEVQQAAALADSPVNLADEAATV
HCCCCEEECCCCCCHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHH
TSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
CCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIE
EECCCCCHHHHHHHHEEEEECCCCCCCHHEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHH
AVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFE
HHHCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHILDAAITAAVTLSRRFLTGR
HHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
QLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
CCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCC
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LSLDVDVRTVAAVIADWTGVPLGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRA
EEECCHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEKSLITINLSEYQEAHTVSQL
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHH
KGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
CCCCCCEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
IDFRNTVMVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYR
EECCCEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PLNAPALRTIVEMKLAQVANRLKKHYGLHCTLEASLYDTLVAACLLPDTGARNIDSLLNQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHH
QILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGGEK
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]