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The map label for this gene is cheD

Identifier: 51597365

GI number: 51597365

Start: 3602717

End: 3604360

Strand: Reverse

Name: cheD

Synonym: YPTB3051

Alternate gene names: 51597365

Gene position: 3604360-3602717 (Counterclockwise)

Preceding gene: 51597366

Following gene: 51597362

Centisome position: 75.97

GC content: 45.62

Gene sequence:

>1644_bases
ATGAGTAAACTTTCGCTTTCTGAATCTAGATTGGGAATATTATTTGGTTTTACTTTAGTGATTAGTCTATTTTCTTTGTT
GCAGATCTTCTCCATAGGTTATTTATCTCATATTTTAAAGAGTACCAAAGCGAATGTAGAGATAACGCACCGTAATCATC
AACAAGAGGCGTTGATGGATCGTGCGCGGATGGAACTATTAATTGCCAGTGACAAGCTTAATCGTGCGGGTATCTATTAT
ATGGAAGATAAAGAGACCGGCTCCGAAGGCAGTTGGCAAAGTCTTCTCAATGAGGCATTGCAGTCATTGCAGCAATCTCA
GGACAGCTATCTGCAGTTGCAGGCGGTTTCCGCCCAAGACAGTAGACAAGAATTGAATGAACTTAAGGAGAGCTACCATC
AGTTGTATCAGGGGCTGGCTGAAATAGCGCAGGGGTTAGCGCAAAAGCACAATATTGACACCTTCTTTGACGTGCCTATC
CAGGGCTTTCAGAGCGACTTCACCGAGAAGTACTACCGCTATTTACAGGAAAGTGAAAAGGGCAGCACTGCTATGGATGA
GCAGCTCTTGTCCTCACTGTCTTCAGCTAAACAGATCATTATTGGTGCACTGGCCATATTGTTGGTACTGGCTTTCTCTG
CCTGGCTAGGCGTCACCCGTTGGATGATTGCGCCCTTAAATCACCTTATCTCACGTATCAATAAGATTGCTGCCGGGGAT
TTATCACACCGTATTGAAGACACGTCTTTTGCTTGCCGAGAAATTAGACAACTCACTTATAGTGTAAGACATATGCAAGA
GGGGCTAGTTGCATTGGTTAGCCAGGTCCGAGGTGGAGCTGAGGTGATCCTGACCGGTGTGAACCAGATTACGGCTGATA
ACCATCGTCTCTCTGAACAAACGTACTCACAAACTCAATCATTGGCGGTGACGGCGCAAAGTATGCAGCAGCTTACCGTC
AGGGTTAAACAAAACTCCATGAGTGCCGAGCAGGCGAATCATCTGGTGAATGAAGCTAGAGATACGGCCAGTCAGGGAGG
AGAGATGATGTCTAATGTGGTGAGTTCAATGGCCGATATTTCCACGGGTTCACGGGAGATAAGCGAAATTATTACACTTA
TTGAGTCGGTTGCTTTTCAGACCAATATTTTGGCATTAAATGCAGCAATTGAAGCCGCTCATGCGGGTGAACACGGCCGT
GGGTTCTCTGTTGTGGCACGTGAGGTCGGTACATTGGCTCACCAAAGTGGCCATTCAGCACAAAATATTAAGCGCCTTAT
TCAGCATTCTGCCAACTCAGTTTCTACGGGGGCCTCGCTGGTTAATCGTTCCGGTGAGAATTTACAGGCTATTATTGATG
TGGTGAAGAAAGTCACCGATTTAATGGCGGAAATAACTACCGCATCACATTATCAAAGCAAAGGAATTGAGGAGATGGCC
GCGCAGGTAGAGATGATTAATGGCGCAACAAAACAGAATGCAGCATTGGTTGAGCAATCAGCACACGCATCGGAAGTGTT
GCAACAGCAGACCTTACAGCTTAATCAGTCGGTAGCCCGCTTTCATTTACCTGTAGAAAAATACTCTCCTCTACGATTAG
CAAAGGAGAGCACGATTGCTGCTATTGATTCACGCGTTAGTTAA

Upstream 100 bases:

>100_bases
TCATAGTGAGCTGCTAGCATGGATATCTCTATCATGACCCAATGTGAATAACATGTTTTCACGCATGAATTATGTTGTTA
AAAAATATTTTGGCTACATT

Downstream 100 bases:

>100_bases
CCTGTTGATCCAACCCGGTTGATTACCGAAATAATCGCCTGCAGGTACAACTGTCATCTTGCCTGCAGCATCTTGCAATA
TAAATGTTGGGAAGCCGTGC

Product: methyl-accepting chemotaxis protein.

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKSTKANVEITHRNHQQEALMDRARMELLIASDKLNRAGIYY
MEDKETGSEGSWQSLLNEALQSLQQSQDSYLQLQAVSAQDSRQELNELKESYHQLYQGLAEIAQGLAQKHNIDTFFDVPI
QGFQSDFTEKYYRYLQESEKGSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRWMIAPLNHLISRINKIAAGD
LSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAEVILTGVNQITADNHRLSEQTYSQTQSLAVTAQSMQQLTV
RVKQNSMSAEQANHLVNEARDTASQGGEMMSNVVSSMADISTGSREISEIITLIESVAFQTNILALNAAIEAAHAGEHGR
GFSVVAREVGTLAHQSGHSAQNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDLMAEITTASHYQSKGIEEMA
AQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARFHLPVEKYSPLRLAKESTIAAIDSRVS

Sequences:

>Translated_547_residues
MSKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKSTKANVEITHRNHQQEALMDRARMELLIASDKLNRAGIYY
MEDKETGSEGSWQSLLNEALQSLQQSQDSYLQLQAVSAQDSRQELNELKESYHQLYQGLAEIAQGLAQKHNIDTFFDVPI
QGFQSDFTEKYYRYLQESEKGSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRWMIAPLNHLISRINKIAAGD
LSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAEVILTGVNQITADNHRLSEQTYSQTQSLAVTAQSMQQLTV
RVKQNSMSAEQANHLVNEARDTASQGGEMMSNVVSSMADISTGSREISEIITLIESVAFQTNILALNAAIEAAHAGEHGR
GFSVVAREVGTLAHQSGHSAQNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDLMAEITTASHYQSKGIEEMA
AQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARFHLPVEKYSPLRLAKESTIAAIDSRVS
>Mature_546_residues
SKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKSTKANVEITHRNHQQEALMDRARMELLIASDKLNRAGIYYM
EDKETGSEGSWQSLLNEALQSLQQSQDSYLQLQAVSAQDSRQELNELKESYHQLYQGLAEIAQGLAQKHNIDTFFDVPIQ
GFQSDFTEKYYRYLQESEKGSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRWMIAPLNHLISRINKIAAGDL
SHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAEVILTGVNQITADNHRLSEQTYSQTQSLAVTAQSMQQLTVR
VKQNSMSAEQANHLVNEARDTASQGGEMMSNVVSSMADISTGSREISEIITLIESVAFQTNILALNAAIEAAHAGEHGRG
FSVVAREVGTLAHQSGHSAQNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDLMAEITTASHYQSKGIEEMAA
QVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARFHLPVEKYSPLRLAKESTIAAIDSRVS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=537, Percent_Identity=40.4096834264432, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1788195, Length=545, Percent_Identity=33.9449541284404, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI1788194, Length=529, Percent_Identity=35.9168241965974, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1787690, Length=325, Percent_Identity=43.3846153846154, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI1789453, Length=328, Percent_Identity=35.0609756097561, Blast_Score=182, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60144; Mature: 60013

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKSTKANVEITHRNHQQEALMD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
RARMELLIASDKLNRAGIYYMEDKETGSEGSWQSLLNEALQSLQQSQDSYLQLQAVSAQD
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHEEEEECCCHH
SRQELNELKESYHQLYQGLAEIAQGLAQKHNIDTFFDVPIQGFQSDFTEKYYRYLQESEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHCCC
GSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRWMIAPLNHLISRINKIAAGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAEVILTGVNQITADNHRLSEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCHHHHCCCHHHHHH
TYSQTQSLAVTAQSMQQLTVRVKQNSMSAEQANHLVNEARDTASQGGEMMSNVVSSMADI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STGSREISEIITLIESVAFQTNILALNAAIEAAHAGEHGRGFSVVAREVGTLAHQSGHSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCH
QNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDLMAEITTASHYQSKGIEEMA
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARFHLPVEKYSPLRLAKESTIA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHH
AIDSRVS
HHHCCCC
>Mature Secondary Structure 
SKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKSTKANVEITHRNHQQEALMD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
RARMELLIASDKLNRAGIYYMEDKETGSEGSWQSLLNEALQSLQQSQDSYLQLQAVSAQD
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHEEEEECCCHH
SRQELNELKESYHQLYQGLAEIAQGLAQKHNIDTFFDVPIQGFQSDFTEKYYRYLQESEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHCCC
GSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRWMIAPLNHLISRINKIAAGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAEVILTGVNQITADNHRLSEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCHHHHCCCHHHHHH
TYSQTQSLAVTAQSMQQLTVRVKQNSMSAEQANHLVNEARDTASQGGEMMSNVVSSMADI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STGSREISEIITLIESVAFQTNILALNAAIEAAHAGEHGRGFSVVAREVGTLAHQSGHSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCH
QNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDLMAEITTASHYQSKGIEEMA
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARFHLPVEKYSPLRLAKESTIA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHH
AIDSRVS
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]