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The map label for this gene is ureC

Identifier: 51597257

GI number: 51597257

Start: 3474039

End: 3475757

Strand: Reverse

Name: ureC

Synonym: YPTB2942

Alternate gene names: 51597257

Gene position: 3475757-3474039 (Counterclockwise)

Preceding gene: 51597258

Following gene: 51597256

Centisome position: 73.26

GC content: 52.18

Gene sequence:

>1719_bases
ATGCCTCAAATTTCTCGGCAAGAATACGCGGGTCTATTTGGCCCAACAACTGGCGATAAAATCCGTTTGGGTGATACCAA
TCTGTTTATCGAAATCGAAAAAGACTTGCGTGGATATGGTGAAGAGTCGGTTTACGGTGGTGGGAAATCGCTGCGTGACG
GGATGGGGGCCAACAATAATCTGACCCGCGATAATGGTGTGCTTGACCTGGTGATTACCAACGTCACGATTGTCGATGCT
CGCTTAGGGGTGATTAAAGCTGACGTCGGTATCCGCGATGGCAAAATCGCCGGTATCGGTAAGAGCGGTAACCCCGGTGT
TATGGATGGGGTGACGCAGGGTATGGTGGTCGGTGTGAGCACCGATGCTATCTCTGGTGAGCATTTGATTCTTACTGCCG
CCGGTATCGATAGCCATATTCATCTCATCTCCCCGCAACAGGCCTATCATGCGCTGTCCAACGGTGTTGCGACATTCTTT
GGTGGGGGGATTGGTCCAACGGATGGCACTAACGGGACAACCGTAACACCAGGGCCGTGGAATATCCGTCAAATGCTGCG
TTCGATAGAGGGGTTACCTGTCAACGTTGGTATTTTGGGGAAAGGTAATTCATACGGGCGCGGCCCGTTGCTGGAACAGG
CTATTGCCGGTGTTGTGGGCTATAAAGTTCATGAAGACTGGGGCGCGACGGCGAATGCTTTGCGTCATGCGCTGCGGATG
GCGGATGAGGTGGATATTCAGGTTTCGGTTCATACCGATAGCCTGAATGAATGTGGTTATGTAGAAGATACTATCGATGC
GTTCGAAGGTCGCACGATCCACACGTTCCACACCGAAGGGGCGGGTGGGGGCCATGCGCCGGATATTATTCGGGTGGCCA
GCCAAACTAACGTACTGCCAAGTTCAACCAACCCCACCCTGCCGTATGGTGTTAACAGCCAGGCTGAGCTGTTTGACATG
ATTATGGTGTGTCACAACCTTAACCCGAACGTACCTGCTGACGTCTCCTTTGCCGAAAGCCGTGTGCGCCCAGAAACGAT
TGCTGCTGAAAACGTTCTGCACGATATGGGCGTTATCTCCATGTTCTCCAGTGACTCACAAGCCATGGGGCGAGTGGGGG
AGAACTGGTTGCGTATTTTGCAAACCGCGGATGCGATGAAAGCGGCTCGGGGCAAATTGCCGGAAGATGCGGCGGGTAAC
GATAATTTCCGCGTGCTGCGCTATGTGGCAAAAATCACCATTAACCCCGCGATTACACAGGGGGTTAGCCATGTTATCGG
ATCGGTTGAAGTGGGAAAAATGGCCGATCTGGTGTTATGGGATCCTCGCTTCTTTGGTGCGAAACCGAAGATGGTTATCA
AGGGTGGCATGATTAACTGGGCCGCGATGGGCGATCCAAATGCGTCACTGCCAACACCACAGCCAGTGTTCTACCGCCCA
ATGTTTGGCGCGATGGGCAAAACGCTACAAGACACTTGTGTCACTTTCGTTTCTCAGGCTGCACTTGATGATGGTGTGAA
AGAGAAAGCGGGGCTGGATCGCCAAGTGATAGCGGTTAAAAACTGCCGCACGATCTCCAAACGTGATCTGGTGCGTAATG
ACCAAACACCAAACATTGAAGTGGATCCTGAAACCTTTGCAGTAAAAGTGGATGGGGTACATGCCACCTGTGAGCCAATT
GCAACTGCGTCGATGAATCAGCGCTATTTCTTTGGCTAA

Upstream 100 bases:

>100_bases
CATCTAAATAACGCCTTGTTTACAGAGCAAATCATCGAAATTCGCATACGTGTAATGGGGTAAAGCAGTTACACGCACCG
GAAAAAGAAAGGAGCGACAG

Downstream 100 bases:

>100_bases
CCTCTCTTTGGCTAATCTGAGGTAGCAGCGTTAATCCCGTTACCGGGGCGTTGTAATACTCAAAGTAAGTAGGGTACTAC
CCGGTTTCAGCATTCAGTTT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MPQISRQEYAGLFGPTTGDKIRLGDTNLFIEIEKDLRGYGEESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIVDA
RLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTQGMVVGVSTDAISGEHLILTAAGIDSHIHLISPQQAYHALSNGVATFF
GGGIGPTDGTNGTTVTPGPWNIRQMLRSIEGLPVNVGILGKGNSYGRGPLLEQAIAGVVGYKVHEDWGATANALRHALRM
ADEVDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHTEGAGGGHAPDIIRVASQTNVLPSSTNPTLPYGVNSQAELFDM
IMVCHNLNPNVPADVSFAESRVRPETIAAENVLHDMGVISMFSSDSQAMGRVGENWLRILQTADAMKAARGKLPEDAAGN
DNFRVLRYVAKITINPAITQGVSHVIGSVEVGKMADLVLWDPRFFGAKPKMVIKGGMINWAAMGDPNASLPTPQPVFYRP
MFGAMGKTLQDTCVTFVSQAALDDGVKEKAGLDRQVIAVKNCRTISKRDLVRNDQTPNIEVDPETFAVKVDGVHATCEPI
ATASMNQRYFFG

Sequences:

>Translated_572_residues
MPQISRQEYAGLFGPTTGDKIRLGDTNLFIEIEKDLRGYGEESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIVDA
RLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTQGMVVGVSTDAISGEHLILTAAGIDSHIHLISPQQAYHALSNGVATFF
GGGIGPTDGTNGTTVTPGPWNIRQMLRSIEGLPVNVGILGKGNSYGRGPLLEQAIAGVVGYKVHEDWGATANALRHALRM
ADEVDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHTEGAGGGHAPDIIRVASQTNVLPSSTNPTLPYGVNSQAELFDM
IMVCHNLNPNVPADVSFAESRVRPETIAAENVLHDMGVISMFSSDSQAMGRVGENWLRILQTADAMKAARGKLPEDAAGN
DNFRVLRYVAKITINPAITQGVSHVIGSVEVGKMADLVLWDPRFFGAKPKMVIKGGMINWAAMGDPNASLPTPQPVFYRP
MFGAMGKTLQDTCVTFVSQAALDDGVKEKAGLDRQVIAVKNCRTISKRDLVRNDQTPNIEVDPETFAVKVDGVHATCEPI
ATASMNQRYFFG
>Mature_571_residues
PQISRQEYAGLFGPTTGDKIRLGDTNLFIEIEKDLRGYGEESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIVDAR
LGVIKADVGIRDGKIAGIGKSGNPGVMDGVTQGMVVGVSTDAISGEHLILTAAGIDSHIHLISPQQAYHALSNGVATFFG
GGIGPTDGTNGTTVTPGPWNIRQMLRSIEGLPVNVGILGKGNSYGRGPLLEQAIAGVVGYKVHEDWGATANALRHALRMA
DEVDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHTEGAGGGHAPDIIRVASQTNVLPSSTNPTLPYGVNSQAELFDMI
MVCHNLNPNVPADVSFAESRVRPETIAAENVLHDMGVISMFSSDSQAMGRVGENWLRILQTADAMKAARGKLPEDAAGND
NFRVLRYVAKITINPAITQGVSHVIGSVEVGKMADLVLWDPRFFGAKPKMVIKGGMINWAAMGDPNASLPTPQPVFYRPM
FGAMGKTLQDTCVTFVSQAALDDGVKEKAGLDRQVIAVKNCRTISKRDLVRNDQTPNIEVDPETFAVKVDGVHATCEPIA
TASMNQRYFFG

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 61020; Mature: 60889

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQISRQEYAGLFGPTTGDKIRLGDTNLFIEIEKDLRGYGEESVYGGGKSLRDGMGANNN
CCCCCCHHHCCCCCCCCCCEEEECCCEEEEEEEHHHCCCCCCCCCCCCHHHHHCCCCCCC
LTRDNGVLDLVITNVTIVDARLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTQGMVVGVS
CCCCCCEEEEEEEEEEEEEEECCEEEECCCCCCCEEEECCCCCCCCHHHHCCCCEEEEEE
TDAISGEHLILTAAGIDSHIHLISPQQAYHALSNGVATFFGGGIGPTDGTNGTTVTPGPW
CCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHCCHHHHHCCCCCCCCCCCCCEECCCCH
NIRQMLRSIEGLPVNVGILGKGNSYGRGPLLEQAIAGVVGYKVHEDWGATANALRHALRM
HHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHH
ADEVDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHTEGAGGGHAPDIIRVASQTNVLP
HCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCHHEEECCCCCCCC
SSTNPTLPYGVNSQAELFDMIMVCHNLNPNVPADVSFAESRVRPETIAAENVLHDMGVIS
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHE
MFSSDSQAMGRVGENWLRILQTADAMKAARGKLPEDAAGNDNFRVLRYVAKITINPAITQ
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEHHHCCCHHHHH
GVSHVIGSVEVGKMADLVLWDPRFFGAKPKMVIKGGMINWAAMGDPNASLPTPQPVFYRP
HHHHHHCCCCCCCCCEEEEECCHHCCCCCCEEEECCEEEEEEECCCCCCCCCCCCEEECC
MFGAMGKTLQDTCVTFVSQAALDDGVKEKAGLDRQVIAVKNCRTISKRDLVRNDQTPNIE
HHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCEE
VDPETFAVKVDGVHATCEPIATASMNQRYFFG
ECCCEEEEEECCCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
PQISRQEYAGLFGPTTGDKIRLGDTNLFIEIEKDLRGYGEESVYGGGKSLRDGMGANNN
CCCCCHHHCCCCCCCCCCEEEECCCEEEEEEEHHHCCCCCCCCCCCCHHHHHCCCCCCC
LTRDNGVLDLVITNVTIVDARLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTQGMVVGVS
CCCCCCEEEEEEEEEEEEEEECCEEEECCCCCCCEEEECCCCCCCCHHHHCCCCEEEEEE
TDAISGEHLILTAAGIDSHIHLISPQQAYHALSNGVATFFGGGIGPTDGTNGTTVTPGPW
CCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHCCHHHHHCCCCCCCCCCCCCEECCCCH
NIRQMLRSIEGLPVNVGILGKGNSYGRGPLLEQAIAGVVGYKVHEDWGATANALRHALRM
HHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHH
ADEVDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHTEGAGGGHAPDIIRVASQTNVLP
HCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCHHEEECCCCCCCC
SSTNPTLPYGVNSQAELFDMIMVCHNLNPNVPADVSFAESRVRPETIAAENVLHDMGVIS
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHE
MFSSDSQAMGRVGENWLRILQTADAMKAARGKLPEDAAGNDNFRVLRYVAKITINPAITQ
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEHHHCCCHHHHH
GVSHVIGSVEVGKMADLVLWDPRFFGAKPKMVIKGGMINWAAMGDPNASLPTPQPVFYRP
HHHHHHCCCCCCCCCEEEEECCHHCCCCCCEEEECCEEEEEEECCCCCCCCCCCCEEECC
MFGAMGKTLQDTCVTFVSQAALDDGVKEKAGLDRQVIAVKNCRTISKRDLVRNDQTPNIE
HHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCEE
VDPETFAVKVDGVHATCEPIATASMNQRYFFG
ECCCEEEEEECCCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA