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The map label for this gene is kch

Identifier: 51597249

GI number: 51597249

Start: 3465723

End: 3466898

Strand: Reverse

Name: kch

Synonym: YPTB2934

Alternate gene names: 51597249

Gene position: 3466898-3465723 (Counterclockwise)

Preceding gene: 51597251

Following gene: 51597246

Centisome position: 73.07

GC content: 41.5

Gene sequence:

>1176_bases
ATGAAAACATTACGGGAATTTAGAGCTAAGGTATCGATACCCATTTTTCTTGCCATTTTGGTGGCAATTAACGGGTATCT
GATTTTAAGCCCGGTACTCTATCGGGCGATTGCACATTCAAGCGATGCAATAAATAACTTCAATACTTGGAAGGAGGCGT
TAAGTTTTCTGGAATTATTTGAAATCCCGCAATTTATGATCGGTCTGGTCTTGATATTGATGGCATATGCACTATCAATG
AAAACCCGTACAGCATGGTTTTTATCGGTATTGCTGCTATTTACTCTTGTTGCCATCAATATTTTTATCGCGAAAAAATA
TGATAGCCTGACGATTTACTCCATCGTGATTATCTTAGCACTGCTCTTTTATTGGCGGCGGTTTGATTATTACAGTCTCG
GCAGCGGTACATTCTTTGCTGTTGTGAGTATCGCTTCATTAATCGTCTATAGCATGCTGGGTACGCTCTATATGGGTGAT
GAGTTTGCCCCCGTGGTGACTGATTTATCTACAGCATTCTATTTCGCGATAGTGTGTATGTCGACGGTGGGGTTCGGGGA
TATTATCCCGCATACCACTGTGGCGAGAATGTTTACTCTTACGGTGATTATTGCTGGTATAACTGTTTTTGCTACCTCAG
TGGCTTCGATTGCCGGCCCGATGATCAGTAATAATATCAAACGCATAGTTAAAGGTAGGATTTCTCACGTGGAACGTAAA
AATCATTTTATTATTGTCGGTACCAACTGTTTGGCACTGAATGTATATAAAGGTCTGCGTGACCGGGGTGATGATGTCAC
TGTGGTTTGTGCGGTAGGTAGCCAACATGATTTCCCTTCCGATGCTGATATTATCGAGGGTGACCCTTCTTCTGTTGCCA
CGCTAAAATTAGCCGGTGCGGCGAAGGCAAAATATATTATCGTGTTGTGTAACAATGATGCTGATAACACCTTTACCATT
TTAGCGGCTAAAGAAATTTCGGGTGAGGGGACGAAAATACTGGCATTAGTCAATGAAACTCAGAATATAGAAAAAGTTAA
AAGAGTCAATCCAGACATGGTCTTCTCTTTGCCATTGTTAGGCAGTGAGTTACTGGTCAGGACTCTGAATGGCGATACCA
TCAATAATACCCTTATTACGGAAATGTTCTTTGGTCATTGCCAGAAACTGGATTGA

Upstream 100 bases:

>100_bases
TATCATTTGATTTCTATCAAAAATAATTTAATTTAATCATGGTTTTTCTCGTTTCTTATCTATACTAAAATTACCTATAA
CAATTCTAGTTACTCTATCG

Downstream 100 bases:

>100_bases
TATCATTAATAGCCCACTATCACTGTGTTTATATCAAAACACCCTCGGTTAAGTGAGGGTGTTTTTTTTGTCACGAGCCT
TGGTTTTTATGGGCTATTTA

Product: voltage-gated potassium channel

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKTLREFRAKVSIPIFLAILVAINGYLILSPVLYRAIAHSSDAINNFNTWKEALSFLELFEIPQFMIGLVLILMAYALSM
KTRTAWFLSVLLLFTLVAINIFIAKKYDSLTIYSIVIILALLFYWRRFDYYSLGSGTFFAVVSIASLIVYSMLGTLYMGD
EFAPVVTDLSTAFYFAIVCMSTVGFGDIIPHTTVARMFTLTVIIAGITVFATSVASIAGPMISNNIKRIVKGRISHVERK
NHFIIVGTNCLALNVYKGLRDRGDDVTVVCAVGSQHDFPSDADIIEGDPSSVATLKLAGAAKAKYIIVLCNNDADNTFTI
LAAKEISGEGTKILALVNETQNIEKVKRVNPDMVFSLPLLGSELLVRTLNGDTINNTLITEMFFGHCQKLD

Sequences:

>Translated_391_residues
MKTLREFRAKVSIPIFLAILVAINGYLILSPVLYRAIAHSSDAINNFNTWKEALSFLELFEIPQFMIGLVLILMAYALSM
KTRTAWFLSVLLLFTLVAINIFIAKKYDSLTIYSIVIILALLFYWRRFDYYSLGSGTFFAVVSIASLIVYSMLGTLYMGD
EFAPVVTDLSTAFYFAIVCMSTVGFGDIIPHTTVARMFTLTVIIAGITVFATSVASIAGPMISNNIKRIVKGRISHVERK
NHFIIVGTNCLALNVYKGLRDRGDDVTVVCAVGSQHDFPSDADIIEGDPSSVATLKLAGAAKAKYIIVLCNNDADNTFTI
LAAKEISGEGTKILALVNETQNIEKVKRVNPDMVFSLPLLGSELLVRTLNGDTINNTLITEMFFGHCQKLD
>Mature_391_residues
MKTLREFRAKVSIPIFLAILVAINGYLILSPVLYRAIAHSSDAINNFNTWKEALSFLELFEIPQFMIGLVLILMAYALSM
KTRTAWFLSVLLLFTLVAINIFIAKKYDSLTIYSIVIILALLFYWRRFDYYSLGSGTFFAVVSIASLIVYSMLGTLYMGD
EFAPVVTDLSTAFYFAIVCMSTVGFGDIIPHTTVARMFTLTVIIAGITVFATSVASIAGPMISNNIKRIVKGRISHVERK
NHFIIVGTNCLALNVYKGLRDRGDDVTVVCAVGSQHDFPSDADIIEGDPSSVATLKLAGAAKAKYIIVLCNNDADNTFTI
LAAKEISGEGTKILALVNETQNIEKVKRVNPDMVFSLPLLGSELLVRTLNGDTINNTLITEMFFGHCQKLD

Specific function: May play a role in the defense against osmotic shock [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=381, Percent_Identity=37.5328083989501, Blast_Score=234, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 43096; Mature: 43096

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLREFRAKVSIPIFLAILVAINGYLILSPVLYRAIAHSSDAINNFNTWKEALSFLELF
CCCHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
EIPQFMIGLVLILMAYALSMKTRTAWFLSVLLLFTLVAINIFIAKKYDSLTIYSIVIILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LLFYWRRFDYYSLGSGTFFAVVSIASLIVYSMLGTLYMGDEFAPVVTDLSTAFYFAIVCM
HHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
STVGFGDIIPHTTVARMFTLTVIIAGITVFATSVASIAGPMISNNIKRIVKGRISHVERK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NHFIIVGTNCLALNVYKGLRDRGDDVTVVCAVGSQHDFPSDADIIEGDPSSVATLKLAGA
CCEEEEECCEEEEHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECC
AKAKYIIVLCNNDADNTFTILAAKEISGEGTKILALVNETQNIEKVKRVNPDMVFSLPLL
CCEEEEEEEECCCCCCEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHCCCCCEEECCCC
GSELLVRTLNGDTINNTLITEMFFGHCQKLD
CHHHHHEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTLREFRAKVSIPIFLAILVAINGYLILSPVLYRAIAHSSDAINNFNTWKEALSFLELF
CCCHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
EIPQFMIGLVLILMAYALSMKTRTAWFLSVLLLFTLVAINIFIAKKYDSLTIYSIVIILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LLFYWRRFDYYSLGSGTFFAVVSIASLIVYSMLGTLYMGDEFAPVVTDLSTAFYFAIVCM
HHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
STVGFGDIIPHTTVARMFTLTVIIAGITVFATSVASIAGPMISNNIKRIVKGRISHVERK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NHFIIVGTNCLALNVYKGLRDRGDDVTVVCAVGSQHDFPSDADIIEGDPSSVATLKLAGA
CCEEEEECCEEEEHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECC
AKAKYIIVLCNNDADNTFTILAAKEISGEGTKILALVNETQNIEKVKRVNPDMVFSLPLL
CCEEEEEEEECCCCCCEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHCCCCCEEECCCC
GSELLVRTLNGDTINNTLITEMFFGHCQKLD
CHHHHHEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8170937; 9097039; 9278503 [H]