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The map label for this gene is ail

Identifier: 51597183

GI number: 51597183

Start: 3392902

End: 3393450

Strand: Reverse

Name: ail

Synonym: YPTB2867

Alternate gene names: 51597183

Gene position: 3393450-3392902 (Counterclockwise)

Preceding gene: 51597184

Following gene: 51597182

Centisome position: 71.52

GC content: 40.62

Gene sequence:

>549_bases
ATGGTTTTTATGAATAAGACATTACTGGTCTCTTCTTTAATTGCATGTTTATCAATTGCGTCTGTTAATGTGTATGCCGA
AGGCGAAAGCAGTATTTCTATTGGATATGCTCAAAGTCGTGTCAAGGAAGATGGGTACAAGTTGGATAAAAATCCAAGAG
GTTTCAACCTGAAGTATCGTTATGAATTCAATAATGACTGGGGAGTGATAGGTTCATTTGCTCAGACTCGCCGGGGGTTC
GAGGAATCTGTTGACGGATTCAAACTTATTGATGGTGATTTTAAGTACTACTCAGTGACTGCGGGGCCTGTTTTCCGCAT
TAACGAGTATGTTAGCTTGTATGGATTATTGGGGGCAGGTCATGGAAAGGCTAAAGTTTCCTCAATATTTGGTCAATCAG
AGAGTAGAAGTAAAACATCTCTGGCATACGGTGCCGGATTACAATTTAATCCACATCCAAATTTTGTCATTGATGCTTCA
TATGAATACTCCAAACTCGATGATGTGAAAGTGGGTACTTGGATGCTTGGCGCGGGTTACCGGTTCTAA

Upstream 100 bases:

>100_bases
TGTACAAATATCCATATTTTCATGTGTCAGATATTTGTTAATATTTGGCTGGCCACTTTAGTCTGTGGTTACTGTATTAG
GTATTGTTATAACAATCTGG

Downstream 100 bases:

>100_bases
CGTCCTCCTAACCATGAAAACCCACCATAATGGTGGTTTCAGATTGCTGACAAAGTCCTGGCCTTATAGCTGGGGCTTTA
AATTAATAGGGGTAGGCTAA

Product: attachment invasion locus protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MVFMNKTLLVSSLIACLSIASVNVYAEGESSISIGYAQSRVKEDGYKLDKNPRGFNLKYRYEFNNDWGVIGSFAQTRRGF
EESVDGFKLIDGDFKYYSVTAGPVFRINEYVSLYGLLGAGHGKAKVSSIFGQSESRSKTSLAYGAGLQFNPHPNFVIDAS
YEYSKLDDVKVGTWMLGAGYRF

Sequences:

>Translated_182_residues
MVFMNKTLLVSSLIACLSIASVNVYAEGESSISIGYAQSRVKEDGYKLDKNPRGFNLKYRYEFNNDWGVIGSFAQTRRGF
EESVDGFKLIDGDFKYYSVTAGPVFRINEYVSLYGLLGAGHGKAKVSSIFGQSESRSKTSLAYGAGLQFNPHPNFVIDAS
YEYSKLDDVKVGTWMLGAGYRF
>Mature_182_residues
MVFMNKTLLVSSLIACLSIASVNVYAEGESSISIGYAQSRVKEDGYKLDKNPRGFNLKYRYEFNNDWGVIGSFAQTRRGF
EESVDGFKLIDGDFKYYSVTAGPVFRINEYVSLYGLLGAGHGKAKVSSIFGQSESRSKTSLAYGAGLQFNPHPNFVIDAS
YEYSKLDDVKVGTWMLGAGYRF

Specific function: Promotes the invasion of pathogenic bacteria into eukaryotic cells by an unknown mechanism

COG id: COG3637

COG function: function code M; Opacity protein and related surface antigens

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ail/ompX/pagC/lom family

Homologues:

Organism=Escherichia coli, GI1787034, Length=179, Percent_Identity=43.0167597765363, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AIL_YERPS (Q56957)

Other databases:

- EMBL:   L49439
- EMBL:   BX936398
- RefSeq:   YP_071374.1
- ProteinModelPortal:   Q56957
- SMR:   Q56957
- GeneID:   2955182
- GenomeReviews:   BX936398_GR
- KEGG:   yps:YPTB2867
- HOGENOM:   HBG685626
- OMA:   HGKAKVS
- ProtClustDB:   CLSK889340
- BioCyc:   YPSE273123:YPTB2867-MONOMER
- GO:   GO:0009405
- InterPro:   IPR000758
- InterPro:   IPR011250
- Gene3D:   G3DSA:2.40.160.20
- PRINTS:   PR00316

Pfam domain/function: PF06316 Ail_Lom

EC number: NA

Molecular weight: Translated: 20194; Mature: 20194

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00694 ENT_VIR_OMP_1; PS00695 ENT_VIR_OMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFMNKTLLVSSLIACLSIASVNVYAEGESSISIGYAQSRVKEDGYKLDKNPRGFNLKYR
CEEECHHHHHHHHHHHHHHHEEEEEECCCCEEEECHHHHHHHCCCEECCCCCCCCEEEEE
YEFNNDWGVIGSFAQTRRGFEESVDGFKLIDGDFKYYSVTAGPVFRINEYVSLYGLLGAG
EEECCCCCEEECHHHHHCCHHHCCCCEEEECCCEEEEEEECCCEEEHHHHHEEEHEECCC
HGKAKVSSIFGQSESRSKTSLAYGAGLQFNPHPNFVIDASYEYSKLDDVKVGTWMLGAGY
CCCHHHHHHHCCCCCCCCCEEEECCCCEECCCCCEEEECCCCCCCCCCEEECEEEECCCC
RF
CC
>Mature Secondary Structure
MVFMNKTLLVSSLIACLSIASVNVYAEGESSISIGYAQSRVKEDGYKLDKNPRGFNLKYR
CEEECHHHHHHHHHHHHHHHEEEEEECCCCEEEECHHHHHHHCCCEECCCCCCCCEEEEE
YEFNNDWGVIGSFAQTRRGFEESVDGFKLIDGDFKYYSVTAGPVFRINEYVSLYGLLGAG
EEECCCCCEEECHHHHHCCHHHCCCCEEEECCCEEEEEEECCCEEEHHHHHEEEHEECCC
HGKAKVSSIFGQSESRSKTSLAYGAGLQFNPHPNFVIDASYEYSKLDDVKVGTWMLGAGY
CCCHHHHHHHCCCCCCCCCEEEECCCCEECCCCCEEEECCCCCCCCCCEEECEEEECCCC
RF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8698470