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The map label for this gene is yegB

Identifier: 51597132

GI number: 51597132

Start: 3330480

End: 3331877

Strand: Direct

Name: yegB

Synonym: YPTB2816

Alternate gene names: 51597132

Gene position: 3330480-3331877 (Clockwise)

Preceding gene: 51597131

Following gene: 51597133

Centisome position: 70.19

GC content: 53.72

Gene sequence:

>1398_bases
ATGGTAACGCAAGCAACATCTGTGCGATGGCAATTGTGGATTGTCGCTTTCGGATTTTTTATGCAGACGCTGGATACCAC
CATCGTCAATACCGCCCTGCCCTCCATCGCAGCCAGTCTGGGCGAAAATCCGTTACGGATGCAATCGGTGATTGTCTCGT
ATGTCCTGACCGTCGCGGTGATGTTGCCCGCCAGTGGTTGGCTGGCGGACCGGATCGGCGTCAAGTGGGTGTTCTTCTCA
GCGATTATTCTGTTCACCTTCGGATCGCTGATGTGCGCGCAATCAGCAACACTGAATGAACTGATCCTCTCCCGTGTGCT
TCAGGGGGTGGGCGACGCAATGATGGTGCCCGTGGGCCGCCTGACGGTGATGAAAATCGTGCCACGCGAGCAATATATGG
CGGCAATGGCGTTTGTCACACTGCCCGGCCAGATTGGGCCATTAGTTGGCCCGGCGCTGGGCGGGTTTTTAGTGGAATTT
GCCAGTTGGCACTGGATTTTCCTGATTAACCTGCCTGTTGGTGTGATCGGCGCATTGGCGACCTTGCTGCTCATGCCTAA
CCACAAAATGTCTACCCGGCGCTTTGATATCAGCGGCTTTATCATGTTGGCAATCGGTATGGCGACCTTAACGCTGGCAC
TGGACGGCCACACGGGACTGGGGTTATCGCCGCTGGCCATCGCGGGGTTGATCCTGTGTGGCGTAATAGCACTGGGCAGC
TATTGGTGGCATGCACTGGGTAATCGTTTCGCACTGTTCTCACTGCACCTGTTCAAGAATAAAATCTATACCCTTGGTTT
GGTCGGGAGTATGTCTGCCCGGATCGGCAGCGGCATGTTGCCATTTATGACGCCTATCTTTCTGCAAATCGGCCTAGGGT
TTAGCCCATTCCACGCGGGGCTGATGATGATCCCGATGATTATCGGCAGCATGGGCATGAAGCGGATTATCGTACAGGTC
GTCAACCGCTTTGGTTACCGGCGAGTCCTGGTCAACGCCACATTATTACTGGCCGTCGTCAGCCTGAGCTTACCGCTCGT
GGCAATCATGGGTTGGACACTGCTGATGCCAGTAGTGTTATTCTTCCAAGGCATGCTCAACGCATTACGCTTTTCCACCA
TGAATACCTTAACCCTAAAAACGTTACCAGATCGTCTGGCTAGCAGCGGTAACAGCCTATTGTCGATGGCGATGCAACTG
TCCATGAGTATCGGGGTCAGTACTGCCGGAATATTATTGGGTACCTTTGCTCATCATCAGGTAGCCACCAACACGCCTGC
CACTCACAGCGCGTTCTTATACAGTTACTTATGTATGGCAATCATTATCGCCCTACCCGCCCTGATATTTAACCGCGTTC
CCCCGGATACAGGAGCCAATCGTCATTTGGCCCGCTAG

Upstream 100 bases:

>100_bases
GATTTATCTCTATTTTGACCGGTTGCGTAACCGTTTTAGCAAGCAACCGCTGATGAAATTGGAATAGTATGCAACAGAGT
GGAAGTAGGAGTGGGGCGCC

Downstream 100 bases:

>100_bases
ATTGGCCGACTGATAAAGACAGGTGAAATTATGATAAGGATCGGCATTACCGGAAAACTGTTTATGGCTATTTTCGCCAC
TTGCATGTTGGTATTGATAA

Product: multidrug efflux system protein MdtE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRIGVKWVFFS
AIILFTFGSLMCAQSATLNELILSRVLQGVGDAMMVPVGRLTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEF
ASWHWIFLINLPVGVIGALATLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGS
YWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAGLMMIPMIIGSMGMKRIIVQV
VNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVLFFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQL
SMSIGVSTAGILLGTFAHHQVATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR

Sequences:

>Translated_465_residues
MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRIGVKWVFFS
AIILFTFGSLMCAQSATLNELILSRVLQGVGDAMMVPVGRLTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEF
ASWHWIFLINLPVGVIGALATLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGS
YWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAGLMMIPMIIGSMGMKRIIVQV
VNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVLFFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQL
SMSIGVSTAGILLGTFAHHQVATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR
>Mature_465_residues
MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRIGVKWVFFS
AIILFTFGSLMCAQSATLNELILSRVLQGVGDAMMVPVGRLTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEF
ASWHWIFLINLPVGVIGALATLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGS
YWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAGLMMIPMIIGSMGMKRIIVQV
VNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVLFFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQL
SMSIGVSTAGILLGTFAHHQVATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI1788392, Length=465, Percent_Identity=71.6129032258065, Blast_Score=628, Evalue=0.0,
Organism=Escherichia coli, GI1790195, Length=452, Percent_Identity=42.6991150442478, Blast_Score=350, Evalue=8e-98,
Organism=Escherichia coli, GI1788710, Length=430, Percent_Identity=31.3953488372093, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789042, Length=393, Percent_Identity=30.7888040712468, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87081983, Length=413, Percent_Identity=26.3922518159806, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788509, Length=136, Percent_Identity=32.3529411764706, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322958, Length=174, Percent_Identity=28.1609195402299, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=164, Percent_Identity=26.219512195122, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=30, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6325455, Length=151, Percent_Identity=32.4503311258278, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50235; Mature: 50235

Theoretical pI: Translated: 10.99; Mature: 10.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MLPASGWLADRIGVKWVFFSAIILFTFGSLMCAQSATLNELILSRVLQGVGDAMMVPVGR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCH
LTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEFASWHWIFLINLPVGVIGALA
HHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
TLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGS
HHHHCCCCCCCCCEECCCHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHH
YWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAG
HHHHHHCCCHHHHHHHHHHCCHHEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
LMMIPMIIGSMGMKRIIVQVVNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVL
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQLSMSIGVSTAGILLGTFAHHQ
HHHHHHHHHHHHHCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MLPASGWLADRIGVKWVFFSAIILFTFGSLMCAQSATLNELILSRVLQGVGDAMMVPVGR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCH
LTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEFASWHWIFLINLPVGVIGALA
HHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
TLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGS
HHHHCCCCCCCCCEECCCHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHH
YWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAG
HHHHHHCCCHHHHHHHHHHCCHHEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
LMMIPMIIGSMGMKRIIVQVVNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVL
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQLSMSIGVSTAGILLGTFAHHQ
HHHHHHHHHHHHHCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA