| Definition | Yersinia pseudotuberculosis IP 32953, complete genome. |
|---|---|
| Accession | NC_006155 |
| Length | 4,744,671 |
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The map label for this gene is tibA [H]
Identifier: 51597064
GI number: 51597064
Start: 3245878
End: 3248088
Strand: Direct
Name: tibA [H]
Synonym: YPTB2746
Alternate gene names: 51597064
Gene position: 3245878-3248088 (Clockwise)
Preceding gene: 51597063
Following gene: 51597070
Centisome position: 68.41
GC content: 44.82
Gene sequence:
>2211_bases ATGAACGCAAACGCCGATTCATGTACTGATTATACTGTCACTGATATTTGTGAGCAGAGTAAATATGGTGCGGGTGAATT TCATAATATTAAGCTGGGTGATGGTGTCACTGCTGGTAGCGAAGATCACCATTTTGTCTTTAATGGTGAAGGATATGAAT TATACAATTCTAACGCGAATTTCTCTGCTCAAATTGCCTCAGGTACCATTCGCTATACCGAAGTGAACAACAGTCACTTT ACTGTAAACGCTCACCATTTTCCGGATGATACCATCTATGCCGGCCGTGCAGAAAATACCACATTGAATGATAGCCTGAT GTGGGTGGCAACATCGGCTGATCAGACACTGGCTAAAGGTAATTCAATGGTCGTTGTTTCCACCCAAATGGCCATGGTTG ATCAAATTTTTGTTACGACGTTGAATGATGGTAGCCTTCCATTTGATCCCGTCATTACCAATAGCCGCTATGAAGATACG TCATATGAAATGTTATGGGGTATGAAAAACGAGGCAAAAGGGTGGGATACCAAAGCCACATCGCATGACTCCGTATTTGT TGATGCCAGCAAGCAGTCTATCGAAGCCAATGGTCACAGTATTGGTGCCACATTTTATGGTAGGGCCACTCAGGTGGTCA AAGCTGGCGGTGAGTCACAGGATACCCACTTATTTGATCACAGTTATTCCTGGGTATATGCCGAGGCTAAATTAACCGGT CTGACGGAGGTTAATGACGCTGCCACTGTCTATCTGAATGCCGCAGCAACTCAAGGTGCTTACGCTGAGAATGTCGTTCT CAACGGCGAAGATACAACATTGATGGTGCGCGCGAGTCTGGATAACAATGCCTATGCCACGGTGGATAACCTAATATTGA ATGGCGGTGAAGTGGTTTTCCAGCAGAGCTCTGGCGACCAATATGCTTCATTAAACATCGGCACACTTTCCGGCTCGGGC TCCTTCCTATTCAATACCTCTATTGCTGAGGGGAAAGGAAACTTCGTGACTATCGCCAATGCCAGTGGGGAACATAAGGT GATAGTTAACGACTCTGGCCATGAGATCACCTCACCTGATATGACCACATTGGACTTGATTCACGATCTCAGTGGTGATG CAACATTCACACTGGCCTCTATTTCTGGAGCTAACATCATTGAAGTCGATGGCGGCACTTACGTATATAGCTTGAATACC TGGGATAATTCCGCACGAGCTGGCGGAAATCTGTGGTATTTAGGCTCAGGTTTGAATACAGGCACTGAGCTTGAACCCGA ACCTGAAGAGAAAACAACCCCGTCAACGGATGCGGTGTTGAGTATGGCCTCATCCAACCAGTTTATTTTCGATGGTGAAA TGCAAAATCTGCGTTTTCGTAAAGGGGATTTAAATAATAATAAAGGTGATGGCGCCAGTGTTTGGGGGCGTTATTTAACC AACAATACTCGGGTCAATGCTGCTCATGATGCCGCTTACCGTTTGCAGCAAGATGGCTTTGAAATTGGTGCTGATAAAGT GCTGGAAATGTCTTCAGGCCAATTAGTCTTGGGCGGTTTTACCTCTTATAGCAATAACCGAGTGAAACATGCTCGTGGTG GGAACAGTACGGTTGATAGTTATAGCTTGGGTGCCTACGGCACTTATTTCGATAACAGTGGTTATTATGTCGATGCCGTC GTTAAAGCCAACCGTTTTAAAAACTCACTGAATGCCCATATGACCAACGGCGGTTCGGTACAAAGTGATTATAACCAGAA TGCAATCGGTGGCTCACTGGAAGCCGGTTATCACTACAGCCTGTCTAATAATTGGTTCGTAGAGCCTTATGTTCGCACCA GCTATTACACGGCACAGGATAAAGATATTGCGCTGAATAATGGCATGACAGCGAATATTGATAATAACCGCTCAGCTAAA GGTGAAATAGGTACACATCTGGGAACGAAGATTGACCTGAATAATGGGGCTATCATCCGCCCTTATGCCAAAGTCGCTAT TGAACGAGAGTTCATCAAATCAAATACCGTGACGATCAATCAGGTTAACGACTTTAATAATGATTTATCAGGACATACCG CGAAGTATGGTTTAGGCATGGATATCAACCTGACGAAACAGACTTCCGTTTATGCCGAAGCCAATTACCGCAACGGGACT CATGTGGAGTCACCTATCATGGCTAATATCGGTTTCCGGATTAATTTCTAA
Upstream 100 bases:
>100_bases AAATTAAAAAATAAATTGGAGTATTATTACATTGAACACCAATAGTAAAAAAACCTACCTTAGCATTGCTATTTCATCCA TTCTTTACGCCTCAACAGCA
Downstream 100 bases:
>100_bases AGAACATACCAGATGAGTGGTTTCCCGCGATAATGCGGGAGACCATTTTTTTGCTCAATAGATTAAACATGTCTACCCAC GTTACTTCGAGCTACATCTT
Product: pertactin family virulence factor/autotransporter
Products: NA
Alternate protein names: Glycoprotein TibA [H]
Number of amino acids: Translated: 736; Mature: 736
Protein sequence:
>736_residues MNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVTAGSEDHHFVFNGEGYELYNSNANFSAQIASGTIRYTEVNNSHF TVNAHHFPDDTIYAGRAENTTLNDSLMWVATSADQTLAKGNSMVVVSTQMAMVDQIFVTTLNDGSLPFDPVITNSRYEDT SYEMLWGMKNEAKGWDTKATSHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGGESQDTHLFDHSYSWVYAEAKLTG LTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVRASLDNNAYATVDNLILNGGEVVFQQSSGDQYASLNIGTLSGSG SFLFNTSIAEGKGNFVTIANASGEHKVIVNDSGHEITSPDMTTLDLIHDLSGDATFTLASISGANIIEVDGGTYVYSLNT WDNSARAGGNLWYLGSGLNTGTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNLRFRKGDLNNNKGDGASVWGRYLT NNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVLGGFTSYSNNRVKHARGGNSTVDSYSLGAYGTYFDNSGYYVDAV VKANRFKNSLNAHMTNGGSVQSDYNQNAIGGSLEAGYHYSLSNNWFVEPYVRTSYYTAQDKDIALNNGMTANIDNNRSAK GEIGTHLGTKIDLNNGAIIRPYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYGLGMDINLTKQTSVYAEANYRNGT HVESPIMANIGFRINF
Sequences:
>Translated_736_residues MNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVTAGSEDHHFVFNGEGYELYNSNANFSAQIASGTIRYTEVNNSHF TVNAHHFPDDTIYAGRAENTTLNDSLMWVATSADQTLAKGNSMVVVSTQMAMVDQIFVTTLNDGSLPFDPVITNSRYEDT SYEMLWGMKNEAKGWDTKATSHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGGESQDTHLFDHSYSWVYAEAKLTG LTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVRASLDNNAYATVDNLILNGGEVVFQQSSGDQYASLNIGTLSGSG SFLFNTSIAEGKGNFVTIANASGEHKVIVNDSGHEITSPDMTTLDLIHDLSGDATFTLASISGANIIEVDGGTYVYSLNT WDNSARAGGNLWYLGSGLNTGTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNLRFRKGDLNNNKGDGASVWGRYLT NNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVLGGFTSYSNNRVKHARGGNSTVDSYSLGAYGTYFDNSGYYVDAV VKANRFKNSLNAHMTNGGSVQSDYNQNAIGGSLEAGYHYSLSNNWFVEPYVRTSYYTAQDKDIALNNGMTANIDNNRSAK GEIGTHLGTKIDLNNGAIIRPYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYGLGMDINLTKQTSVYAEANYRNGT HVESPIMANIGFRINF >Mature_736_residues MNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVTAGSEDHHFVFNGEGYELYNSNANFSAQIASGTIRYTEVNNSHF TVNAHHFPDDTIYAGRAENTTLNDSLMWVATSADQTLAKGNSMVVVSTQMAMVDQIFVTTLNDGSLPFDPVITNSRYEDT SYEMLWGMKNEAKGWDTKATSHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGGESQDTHLFDHSYSWVYAEAKLTG LTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVRASLDNNAYATVDNLILNGGEVVFQQSSGDQYASLNIGTLSGSG SFLFNTSIAEGKGNFVTIANASGEHKVIVNDSGHEITSPDMTTLDLIHDLSGDATFTLASISGANIIEVDGGTYVYSLNT WDNSARAGGNLWYLGSGLNTGTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNLRFRKGDLNNNKGDGASVWGRYLT NNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVLGGFTSYSNNRVKHARGGNSTVDSYSLGAYGTYFDNSGYYVDAV VKANRFKNSLNAHMTNGGSVQSDYNQNAIGGSLEAGYHYSLSNNWFVEPYVRTSYYTAQDKDIALNNGMTANIDNNRSAK GEIGTHLGTKIDLNNGAIIRPYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYGLGMDINLTKQTSVYAEANYRNGT HVESPIMANIGFRINF
Specific function: Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation [H]
COG id: COG3468
COG function: function code MU; Type V secretory pathway, adhesin AidA
Gene ontology:
Cell location: Adhesin/invasin TibA translocator:Cell outer membrane; Multi-pass membrane protein (Potential). Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]
Homologues:
Organism=Escherichia coli, GI87082145, Length=556, Percent_Identity=31.8345323741007, Blast_Score=211, Evalue=2e-55, Organism=Escherichia coli, GI1787452, Length=483, Percent_Identity=25.4658385093168, Blast_Score=85, Evalue=2e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005546 - InterPro: IPR006315 - InterPro: IPR012332 - InterPro: IPR011050 - InterPro: IPR004899 - InterPro: IPR003991 [H]
Pfam domain/function: PF03797 Autotransporter; PF03212 Pertactin [H]
EC number: NA
Molecular weight: Translated: 79663; Mature: 79663
Theoretical pI: Translated: 4.52; Mature: 4.52
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVTAGSEDHHFVFNGEGYELYNSNAN CCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEECCCCC FSAQIASGTIRYTEVNNSHFTVNAHHFPDDTIYAGRAENTTLNDSLMWVATSADQTLAKG EEEEEECCEEEEEEECCCEEEEEEEECCCCCEEECCCCCCEECCCEEEEEECCCHHHHCC NSMVVVSTQMAMVDQIFVTTLNDGSLPFDPVITNSRYEDTSYEMLWGMKNEAKGWDTKAT CCEEEEEEHHHEEEEEEEEEECCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCCCCC SHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGGESQDTHLFDHSYSWVYAEAKLTG CCCEEEEECCCCEEECCCCEEEEEEECCEEEEEECCCCCCCCEEEECCCEEEEEEEEEEC LTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVRASLDNNAYATVDNLILNGGEVVF CEECCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEHEEECCCEEEE QQSSGDQYASLNIGTLSGSGSFLFNTSIAEGKGNFVTIANASGEHKVIVNDSGHEITSPD EECCCCCEEEEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCEEEEECCCCCEECCCC MTTLDLIHDLSGDATFTLASISGANIIEVDGGTYVYSLNTWDNSARAGGNLWYLGSGLNT CCHHHHHHHCCCCCEEEEEEECCCCEEEECCCEEEEEEECCCCCCCCCCCEEEEECCCCC GTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNLRFRKGDLNNNKGDGASVWGRYLT CCCCCCCCCCCCCCCHHHEEEECCCCCEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHC NNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVLGGFTSYSNNRVKHARGGNSTVDS CCCEEEEHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCC YSLGAYGTYFDNSGYYVDAVVKANRFKNSLNAHMTNGGSVQSDYNQNAIGGSLEAGYHYS CCCCCEEEEECCCCEEEEEEEECHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEE LSNNWFVEPYVRTSYYTAQDKDIALNNGMTANIDNNRSAKGEIGTHLGTKIDLNNGAIIR CCCCEEECCEEEEEEEECCCCCEEECCCEEEECCCCCCCCCCCCCCCCCEEECCCCCEEC PYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYGLGMDINLTKQTSVYAEANYRNGT CHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCEEEEECCCCEEEEEECCCCCC HVESPIMANIGFRINF CCCCCEEEECCEEEEC >Mature Secondary Structure MNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVTAGSEDHHFVFNGEGYELYNSNAN CCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEECCCCC FSAQIASGTIRYTEVNNSHFTVNAHHFPDDTIYAGRAENTTLNDSLMWVATSADQTLAKG EEEEEECCEEEEEEECCCEEEEEEEECCCCCEEECCCCCCEECCCEEEEEECCCHHHHCC NSMVVVSTQMAMVDQIFVTTLNDGSLPFDPVITNSRYEDTSYEMLWGMKNEAKGWDTKAT CCEEEEEEHHHEEEEEEEEEECCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCCCCC SHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGGESQDTHLFDHSYSWVYAEAKLTG CCCEEEEECCCCEEECCCCEEEEEEECCEEEEEECCCCCCCCEEEECCCEEEEEEEEEEC LTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVRASLDNNAYATVDNLILNGGEVVF CEECCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEHEEECCCEEEE QQSSGDQYASLNIGTLSGSGSFLFNTSIAEGKGNFVTIANASGEHKVIVNDSGHEITSPD EECCCCCEEEEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCEEEEECCCCCEECCCC MTTLDLIHDLSGDATFTLASISGANIIEVDGGTYVYSLNTWDNSARAGGNLWYLGSGLNT CCHHHHHHHCCCCCEEEEEEECCCCEEEECCCEEEEEEECCCCCCCCCCCEEEEECCCCC GTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNLRFRKGDLNNNKGDGASVWGRYLT CCCCCCCCCCCCCCCHHHEEEECCCCCEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHC NNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVLGGFTSYSNNRVKHARGGNSTVDS CCCEEEEHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCC YSLGAYGTYFDNSGYYVDAVVKANRFKNSLNAHMTNGGSVQSDYNQNAIGGSLEAGYHYS CCCCCEEEEECCCCEEEEEEEECHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEE LSNNWFVEPYVRTSYYTAQDKDIALNNGMTANIDNNRSAKGEIGTHLGTKIDLNNGAIIR CCCCEEECCEEEEEEEECCCCCEEECCCEEEECCCCCCCCCCCCCCCCCEEECCCCCEEC PYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYGLGMDINLTKQTSVYAEANYRNGT CHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCEEEEECCCCEEEEEECCCCCC HVESPIMANIGFRINF CCCCCEEEECCEEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10417177 [H]