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The map label for this gene is flk

Identifier: 51596942

GI number: 51596942

Start: 3099247

End: 3100284

Strand: Direct

Name: flk

Synonym: YPTB2623

Alternate gene names: 51596942

Gene position: 3099247-3100284 (Clockwise)

Preceding gene: 51596941

Following gene: 51596944

Centisome position: 65.32

GC content: 50.39

Gene sequence:

>1038_bases
ATGCAACCTTTGAACGGCCCAGGCGTTCCCATTGGCAATGATCGCCATATCACGCCCACTAAGTTGACCGCCCAATCCAC
GGTGGAAGATCAGGCGCTAACCCCAGCGCAGCGTACTACCTTAGAGAAACTGATCGTACGGATTATGGCCCTCAGCCCCG
TCAAATCGGCCGAGATCTGGGCCGGGCTTCGCCATAACCTCTCCTTGGACGCAACCGGTGATCTCCTTGCACGTCACTTC
CAGCCGGCCGAGCAGCTACTGCAAACCCGCCTGTCTCAAGCACAGGAAAATCATGCTAGCCAACAGCTTCGTCAACAACT
CACTGCATTATTACCACAAGGGAATAACCGGCAGGCAGTCAGTGATTTTATCCGCCAGCAATTCGGCCATACGGTATTAA
GCCAGTTAAGCCACACCGAGTTACAACAAGTCCTGGTGTTATTGCAATCCGGTACGCTGAATATTCCTCAACCACAACTG
ACAACCCTAACCGATAGGCCATTGCTACCCGCCGAGCATCAGAATATTCAATCACTGGTGGCGAAACTCAGTGCCGCAAC
GGGTGAACAACCCACAAAAATCTGGCAAACATTGTTTGATATGGTTGGAGTAAAACATCATGATCCGCTACCCGCTCGCC
ATTTCCAGCTACTGAGCCAGTTCTTGCAAACTAAAGTGGCCCTCAGCCAACAAACTGCCCCAACATTAGTTAACCTGCAA
ACTGCCCTTAAGCAACCAGCCGATGCACAAGAACAGCAGTTATTGGCCGATTACAGCCAAAACCGTTTTCAGGCCAGCCC
AACGACCCCGCTGACACAGGCACAGCTGAACGATATTATCAATATTCTGTTTGCCGCCCGATTAGAGAAGGCCAATGCTG
CCCAATATTTAGATGAAGAACACAAGCCCCTTCAGCCACTGATTAACCCGTTCATTGCCTCACTGCCAGAGTCATTACAG
CCTTTATTACAGAAGCCGTCACTCGTGGTTGTGGCATTGATTATCGTGATAGCCTTTCTATTGGCGATTTTTCTTTGA

Upstream 100 bases:

>100_bases
AGAAGAATATATTGGTCGCGCTCATTTACAGGTATCATAATATCGGCCTGCGCCTACCGCCGGGTTTCCCTTATTTCCTC
CATAGCGAAGGACCGGTTAT

Downstream 100 bases:

>100_bases
GCCACCAATAGCCCTTCCCCCAAGTAAAAAAAACCTGGCTCAGTTCAAGGTGACTATTTAAATACAAAAATACAAAAAGC
GACTAATATCAGTCGCTTTT

Product: flagella biosynthesis regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MQPLNGPGVPIGNDRHITPTKLTAQSTVEDQALTPAQRTTLEKLIVRIMALSPVKSAEIWAGLRHNLSLDATGDLLARHF
QPAEQLLQTRLSQAQENHASQQLRQQLTALLPQGNNRQAVSDFIRQQFGHTVLSQLSHTELQQVLVLLQSGTLNIPQPQL
TTLTDRPLLPAEHQNIQSLVAKLSAATGEQPTKIWQTLFDMVGVKHHDPLPARHFQLLSQFLQTKVALSQQTAPTLVNLQ
TALKQPADAQEQQLLADYSQNRFQASPTTPLTQAQLNDIINILFAARLEKANAAQYLDEEHKPLQPLINPFIASLPESLQ
PLLQKPSLVVVALIIVIAFLLAIFL

Sequences:

>Translated_345_residues
MQPLNGPGVPIGNDRHITPTKLTAQSTVEDQALTPAQRTTLEKLIVRIMALSPVKSAEIWAGLRHNLSLDATGDLLARHF
QPAEQLLQTRLSQAQENHASQQLRQQLTALLPQGNNRQAVSDFIRQQFGHTVLSQLSHTELQQVLVLLQSGTLNIPQPQL
TTLTDRPLLPAEHQNIQSLVAKLSAATGEQPTKIWQTLFDMVGVKHHDPLPARHFQLLSQFLQTKVALSQQTAPTLVNLQ
TALKQPADAQEQQLLADYSQNRFQASPTTPLTQAQLNDIINILFAARLEKANAAQYLDEEHKPLQPLINPFIASLPESLQ
PLLQKPSLVVVALIIVIAFLLAIFL
>Mature_345_residues
MQPLNGPGVPIGNDRHITPTKLTAQSTVEDQALTPAQRTTLEKLIVRIMALSPVKSAEIWAGLRHNLSLDATGDLLARHF
QPAEQLLQTRLSQAQENHASQQLRQQLTALLPQGNNRQAVSDFIRQQFGHTVLSQLSHTELQQVLVLLQSGTLNIPQPQL
TTLTDRPLLPAEHQNIQSLVAKLSAATGEQPTKIWQTLFDMVGVKHHDPLPARHFQLLSQFLQTKVALSQQTAPTLVNLQ
TALKQPADAQEQQLLADYSQNRFQASPTTPLTQAQLNDIINILFAARLEKANAAQYLDEEHKPLQPLINPFIASLPESLQ
PLLQKPSLVVVALIIVIAFLLAIFL

Specific function: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor flgM upon sensing ring completion or hook elongation. Flk could inhibit flgM secretion by acting as a braking system for the flagellar- associated ty

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flk family [H]

Homologues:

Organism=Escherichia coli, GI1788661, Length=318, Percent_Identity=43.0817610062893, Blast_Score=233, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38156; Mature: 38156

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLNGPGVPIGNDRHITPTKLTAQSTVEDQALTPAQRTTLEKLIVRIMALSPVKSAEIW
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHH
AGLRHNLSLDATGDLLARHFQPAEQLLQTRLSQAQENHASQQLRQQLTALLPQGNNRQAV
HHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SDFIRQQFGHTVLSQLSHTELQQVLVLLQSGTLNIPQPQLTTLTDRPLLPAEHQNIQSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHH
AKLSAATGEQPTKIWQTLFDMVGVKHHDPLPARHFQLLSQFLQTKVALSQQTAPTLVNLQ
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TALKQPADAQEQQLLADYSQNRFQASPTTPLTQAQLNDIINILFAARLEKANAAQYLDEE
HHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HKPLQPLINPFIASLPESLQPLLQKPSLVVVALIIVIAFLLAIFL
CCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQPLNGPGVPIGNDRHITPTKLTAQSTVEDQALTPAQRTTLEKLIVRIMALSPVKSAEIW
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHH
AGLRHNLSLDATGDLLARHFQPAEQLLQTRLSQAQENHASQQLRQQLTALLPQGNNRQAV
HHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SDFIRQQFGHTVLSQLSHTELQQVLVLLQSGTLNIPQPQLTTLTDRPLLPAEHQNIQSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHH
AKLSAATGEQPTKIWQTLFDMVGVKHHDPLPARHFQLLSQFLQTKVALSQQTAPTLVNLQ
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TALKQPADAQEQQLLADYSQNRFQASPTTPLTQAQLNDIINILFAARLEKANAAQYLDEE
HHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HKPLQPLINPFIASLPESLQPLLQKPSLVVVALIIVIAFLLAIFL
CCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9079927; 11677609 [H]