Click here to switch to the map view.

The map label for this gene is cscR

Identifier: 51596748

GI number: 51596748

Start: 2869124

End: 2870167

Strand: Direct

Name: cscR

Synonym: YPTB2426

Alternate gene names: 51596748

Gene position: 2869124-2870167 (Clockwise)

Preceding gene: 51596747

Following gene: 51596750

Centisome position: 60.47

GC content: 48.85

Gene sequence:

>1044_bases
ATGGTCTCACTGAAAGAAGTGGCAAATCTAGCCTCTGTTTCATTAATGACCGCATCTCGAGCGATTAATAGCCCAGAGCA
ACTGCGGCCGGAAACGTATCAGCGAGTGATGCAGGCGATTGAATCCCTGAATTATGTGCCTGATTTTGCAGCCCGTAAGA
TGCGCGGCCACGCCACCAAAACATCAACCCTGGCAGTACTCGCCTGGGATACGGCGACCACACCGTTCTCAGTTGAAATA
TTGCTCTCCATTGAGTTAACTGCCCGAGAGTTTGGCTGGAACAGCTTTTTAGTGAACCTAACCTCACGCGAGGACAGCCA
ACGGGCGCTTAACCAACTACTCGCCCAACGGCCCGATGGCATTATTTTTACTGCTATGGGGCTACGTCAGGTCACCATTC
CCGAGCGATTTCGGGATAAAAACATTGTTCTCGCTAATTGCGTCAGTGAAAGCCATTCAATTCCTAGCTACATTCCCGAT
GATTTTGATGGTCAATATCAAGCCATGAAGTTGCTGCTGCAACGCGGATATCAGCGGCCTTTGTGTATTTATCTGCCGGA
GTGTACCTTGGCAGGCAAGGCCCGGCGGGCAGGGGTAGAAAAAGCCTGGCAGGAATCTGCATTACCAACAGAGCAACTCA
ATCAGTGCCATATAGCGTGGGGAGATGAACATTATCAGGATGTCATTCCGCTATTGGAACGCCATTGCCCTAAGGGAAAA
CCTAATTTTGATGTGTTAATTTGCGGCGATGACCGTATCGCATTTTTGGCCTATCAGGTTTTACTGGCCAAAGGTGTGGT
AATTCCACAACAGGTTGCGGTGATCGGCTATGGCGATATGGTTGGTATTGGTGAATTGTATCTACCACCACTGACCACAG
TACAACTCCCCTATTATGATATTGGTCGTCAAGCTGCCCTCCATTTAATAAGAGGACGTGAATCGCGGGCAATACATCGG
TTACCCTGCCCACTACTAGAACGGGGATCCATCCGTGACTCAATGCCTAATAACTGTGTGCCTCTTTTCAGTAAACAGCG
ATAA

Upstream 100 bases:

>100_bases
TTGATAGATAATAGTGATATCACTACAACTATAAAATGAGAGCAACAGCATCACCCATGACAATATAATTACCCTGCCAG
CCTAATCCAGGAGGTACGTA

Downstream 100 bases:

>100_bases
ATAGCGCTCATGGATGCATGCTAAGGACTGATGAGTGGCAAGAACGGGGCTGCGTTATACGGGGCAGCACGCCATAAATA
GTATAAACTTCACGAAAGCA

Product: LacI family sucrose operon repressor

Products: NA

Alternate protein names: Csc operon regulatory protein [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCIYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPNNCVPLFSKQR

Sequences:

>Translated_347_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCIYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPNNCVPLFSKQR
>Mature_347_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCIYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPNNCVPLFSKQR

Specific function: Repressor for the csc operon. Binds D-fructose as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=26.3313609467456, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787948, Length=348, Percent_Identity=27.8735632183908, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=25.2307692307692, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786540, Length=347, Percent_Identity=25.9365994236311, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789068, Length=308, Percent_Identity=27.9220779220779, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789202, Length=306, Percent_Identity=25.4901960784314, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=22.6586102719033, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38962; Mature: 38962

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATK
CCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
TSTLAVLAWDTATTPFSVEILLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDG
CCEEEEEEECCCCCCEEEEEEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
IIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPDDFDGQYQAMKLLLQRGYQRP
EEEEECCCEEECCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
LCIYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
EEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEECCHHHHHHHHHHHHHCCCCC
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYD
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEECCCCCEEECCHHH
IGRQAALHLIRGRESRAIHRLPCPLLERGSIRDSMPNNCVPLFSKQR
HHHHHHHHHHHCCCCCCHHCCCCCHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATK
CCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
TSTLAVLAWDTATTPFSVEILLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDG
CCEEEEEEECCCCCCEEEEEEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
IIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPDDFDGQYQAMKLLLQRGYQRP
EEEEECCCEEECCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
LCIYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
EEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEECCHHHHHHHHHHHHHCCCCC
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYD
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEECCCCCEEECCHHH
IGRQAALHLIRGRESRAIHRLPCPLLERGSIRDSMPNNCVPLFSKQR
HHHHHHHHHHHCCCCCCHHCCCCCHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA