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The map label for this gene is aer

Identifier: 51596746

GI number: 51596746

Start: 2866909

End: 2868489

Strand: Direct

Name: aer

Synonym: YPTB2424

Alternate gene names: 51596746

Gene position: 2866909-2868489 (Clockwise)

Preceding gene: 51596745

Following gene: 51596747

Centisome position: 60.42

GC content: 50.16

Gene sequence:

>1581_bases
ATGAGAGTTAACAAACCTGTCAGCCGGCAGGAGTATCCCATTGAGCGCGATATCACCTTGCAGTCCACCACTGATATTCA
TGGAAATATTGCTTACGCTAATGCTGCTTTTGTTCGTGCCAGTGGCTTTGAATATCAAGAGTTGCAAGGTCAACCTCACA
ATATGGTCAGGCACCCCGATATGCCACCCGCGGCTTTTGCTGATATGTGGCAAACATTGAATGCCGGTCTTTCTTGGTCT
TCATTGGTGAAGAATCGCCGTAAAAATGGAGATTATTACTGGGTCCGGGCTAATGCGACGCCACTGCGCCATAATGGCCG
TTTAACCGGTTATATTTCGGTACGTATTGCGCCAACTCGCGATGAGGTAAAACAAGCTGAAGCATTGTATACCGATTTCA
ACACCGGTAAGGCAAAACGGCGGCATATTGCCTTGTATCGTGGGCTGATCGTGCGCACGGGGTGGCTCTCCCCACTTTCT
TTGTTCCAAACTTTACCATTACGCTGGCGCCTGCGGAGTGCCTTGCTAAGTTCCGCCATCATTCCAACCGCCGCCGCCAG
TGTGATGGAGGTAGCGGGTCAACCTCTCTTGATTCTCGGCTCGGTGGCATTGACCTGGAGCGTATTGGCTTCACTGTGGT
TGGAGCGGCAGATTGCCCGCCCCATCGCGGCTATTTTGCAACAGGCGCAGGACGTTTCCTCCGGAGAAGCAGGCGATTAT
GTACAACTAAATCGTGTCGATGAAATCGGTTATTTAATGCGTAGCGTCAATCAACTCGGCCTGAACCTACGTTCTTTAAC
CGATGATGTCAGTGGTCAGGTTGATGGGATTAATACCGCCAGCAACGAAATTGCTGCTGGCAATCGCGAACTAAAAGTAC
GAACCGAACAAGCAACCGATAATCTGCAACACATTGTCAGTGCCACAGAACAATTAGCTGCGACAGTGCAGAACAGCGCT
AACAGTGCCAATGAAACAACATCACTCGCCGAAATGAGCAGCCATGCCGCAGAAAAAGGCAGCGAGCTCATGCACCAAGT
CATTGAAACTATGGGCACTATCAATGACTCCAGCCATCGCATTGTAGATATTATCAGTGTGATTGAAGGCATTGCTTTTC
AGACCAATATTCTGGCACTCAACGCGGCCGTAGAAGCGGCCCGGGCGGGTGAACAAGGTCGTGGATTTGCCGTAGTTGCC
AGCGAGGTACGCCATTTGGCACAACGTTCGTCAACCGCAGCAAAAGAGATTAAACATTTAATTGAGACCAGTGTAGAGCG
GGTACGTGACGGAAGTACTTTGGTGCAAAATGCCGGTGCCACCATGGATAATATTGTCAAACAGGCAAGCCAGGTCTCTA
CGTTGATCAGTGAAATCAGCACCTCGACTCATGAACAGACACAGGCCCTTGGCCAAATCCGGCAATCGATCAGTCGGCTA
GATCAAATGACTTACCAGAATGCCGCGATGGTTGAGCAATATGCTGGCGCGGCAGAAGAACTGGCACATCGGACATTGCG
ACTAACCGCGGCGGTCCGTATTTACCGCCCATTGAATAACGTAGGAAAGTTAAGGGATTAG

Upstream 100 bases:

>100_bases
GTAAGTAATTCGGATTATTGAACGTAGCCAACGCACAGGTAACTTGAAGTATAACGGGTCTATTGACTACCAGGGATCTC
CTCCCTTTACTGAGGTTAAT

Downstream 100 bases:

>100_bases
ACAGAATCACCGCATTATCTGTTACCCCTATCCCGACTGGCAGGTGATTTATCATAGCAATAATCTAAAACCTCGCTATA
GTGGGTAGGTGGTTATCCAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRASGFEYQELQGQPHNMVRHPDMPPAAFADMWQTLNAGLSWS
SLVKNRRKNGDYYWVRANATPLRHNGRLTGYISVRIAPTRDEVKQAEALYTDFNTGKAKRRHIALYRGLIVRTGWLSPLS
LFQTLPLRWRLRSALLSSAIIPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARPIAAILQQAQDVSSGEAGDY
VQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTASNEIAAGNRELKVRTEQATDNLQHIVSATEQLAATVQNSA
NSANETTSLAEMSSHAAEKGSELMHQVIETMGTINDSSHRIVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
SEVRHLAQRSSTAAKEIKHLIETSVERVRDGSTLVQNAGATMDNIVKQASQVSTLISEISTSTHEQTQALGQIRQSISRL
DQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNVGKLRD

Sequences:

>Translated_526_residues
MRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRASGFEYQELQGQPHNMVRHPDMPPAAFADMWQTLNAGLSWS
SLVKNRRKNGDYYWVRANATPLRHNGRLTGYISVRIAPTRDEVKQAEALYTDFNTGKAKRRHIALYRGLIVRTGWLSPLS
LFQTLPLRWRLRSALLSSAIIPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARPIAAILQQAQDVSSGEAGDY
VQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTASNEIAAGNRELKVRTEQATDNLQHIVSATEQLAATVQNSA
NSANETTSLAEMSSHAAEKGSELMHQVIETMGTINDSSHRIVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
SEVRHLAQRSSTAAKEIKHLIETSVERVRDGSTLVQNAGATMDNIVKQASQVSTLISEISTSTHEQTQALGQIRQSISRL
DQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNVGKLRD
>Mature_526_residues
MRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRASGFEYQELQGQPHNMVRHPDMPPAAFADMWQTLNAGLSWS
SLVKNRRKNGDYYWVRANATPLRHNGRLTGYISVRIAPTRDEVKQAEALYTDFNTGKAKRRHIALYRGLIVRTGWLSPLS
LFQTLPLRWRLRSALLSSAIIPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARPIAAILQQAQDVSSGEAGDY
VQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTASNEIAAGNRELKVRTEQATDNLQHIVSATEQLAATVQNSA
NSANETTSLAEMSSHAAEKGSELMHQVIETMGTINDSSHRIVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
SEVRHLAQRSSTAAKEIKHLIETSVERVRDGSTLVQNAGATMDNIVKQASQVSTLISEISTSTHEQTQALGQIRQSISRL
DQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNVGKLRD

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=508, Percent_Identity=47.4409448818898, Blast_Score=450, Evalue=1e-127,
Organism=Escherichia coli, GI1788195, Length=314, Percent_Identity=46.1783439490446, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1788194, Length=303, Percent_Identity=43.8943894389439, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI2367378, Length=322, Percent_Identity=41.9254658385093, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1787690, Length=323, Percent_Identity=41.1764705882353, Blast_Score=221, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57707; Mature: 57707

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRASGFEYQELQGQPHNMVRHPD
CCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECEEEEEECCCCHHHHCCCCCCCCCCCC
MPPAAFADMWQTLNAGLSWSSLVKNRRKNGDYYWVRANATPLRHNGRLTGYISVRIAPTR
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCH
DEVKQAEALYTDFNTGKAKRRHIALYRGLIVRTGWLSPLSLFQTLPLRWRLRSALLSSAI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHH
IPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARPIAAILQQAQDVSSGEAGDY
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
VQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTASNEIAAGNRELKVRTEQATD
EEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEEEHHHHH
NLQHIVSATEQLAATVQNSANSANETTSLAEMSSHAAEKGSELMHQVIETMGTINDSSHR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRHLAQRSSTAAKEIKHL
HHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IETSVERVRDGSTLVQNAGATMDNIVKQASQVSTLISEISTSTHEQTQALGQIRQSISRL
HHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNVGKLRD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVNKPVSRQEYPIERDITLQSTTDIHGNIAYANAAFVRASGFEYQELQGQPHNMVRHPD
CCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECEEEEEECCCCHHHHCCCCCCCCCCCC
MPPAAFADMWQTLNAGLSWSSLVKNRRKNGDYYWVRANATPLRHNGRLTGYISVRIAPTR
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCH
DEVKQAEALYTDFNTGKAKRRHIALYRGLIVRTGWLSPLSLFQTLPLRWRLRSALLSSAI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHH
IPTAAASVMEVAGQPLLILGSVALTWSVLASLWLERQIARPIAAILQQAQDVSSGEAGDY
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
VQLNRVDEIGYLMRSVNQLGLNLRSLTDDVSGQVDGINTASNEIAAGNRELKVRTEQATD
EEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEEEHHHHH
NLQHIVSATEQLAATVQNSANSANETTSLAEMSSHAAEKGSELMHQVIETMGTINDSSHR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRHLAQRSSTAAKEIKHL
HHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IETSVERVRDGSTLVQNAGATMDNIVKQASQVSTLISEISTSTHEQTQALGQIRQSISRL
HHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DQMTYQNAAMVEQYAGAAEELAHRTLRLTAAVRIYRPLNNVGKLRD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]