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The map label for this gene is cheB

Identifier: 51596721

GI number: 51596721

Start: 2829091

End: 2830140

Strand: Reverse

Name: cheB

Synonym: YPTB2398

Alternate gene names: 51596721

Gene position: 2830140-2829091 (Counterclockwise)

Preceding gene: 51596722

Following gene: 51596720

Centisome position: 59.65

GC content: 53.14

Gene sequence:

>1050_bases
ATGAGTAAAGTCAGAGTATTGTGTGTTGATGATTCTGCATTAATGCGTCAGCTAATGACTGAGATTATTAACAGTCACCC
GGATATGGAGATGGTTGCTGCGGCACAGGATCCGTTGGTTGCCCGTGATTTGATCAAAAAATTTAATCCACAAGTTTTGA
CGCTTGACGTGGAAATGCCTCGCATGGATGGCTTGGATTTTCTCGAGAAATTGATGCGTCTACGGCCCATGCCGGTGGTG
ATGGTGTCTTCCCTAACGGGTAAAAACTCCGAAATAACCATGCGGGCGTTGGAGTTGGGGGCGATTGATTTTGTCACCAA
ACCTCAGTTAGGGATCCGCGAAGGAATGCTGGCTTACAGCGAACTGATTGCCGATAAGATCCGCACGGCGGCTAAGGCTC
GTTTACCACAGCGCGTCCTGGAAAATAAACCGGCGATGCTCAGCCATACCCCATTGCTCAGCAGTGAAAAATTGATCGCC
ATTGGGGCATCAACTGGCGGTACTGAGGCGATTCGTGCGGTATTACAGCCTTTGCCACCAACCAGTCCGGCATTGCTGAT
CACTCAGCATATGCCGCCGGGATTTACCCGTTCGTTTGCTGAACGCTTGAATAAACTGTGCCAAATCACGGTAAAAGAAG
CAGAGGATGGCGAGCGAGTATTACCGGGACATGCCTATATTGCACCCGGTGATCGGCACTTGGAACTGGCCCGGAGTGGT
GCCAACTACCAGGTGCGGATCCATGACGGACCCGCGGTTAATCGTCACCGTCCTTCGGTTGATGTTCTTTTCCGTTCGGT
GGCGCAGTATGCCGGGCGCAATGCGGTCGGGGTGATCCTCACGGGGATGGGCAATGATGGGGCCGCTGGCTTGCTGGAGA
TGCACCGGGCGGGTGCCTACACCCTCGCACAAAATGAGGCCAGCTGCGTGGTCTTTGGTATGCCACGTGAGGCGATTGCG
ATGGGGGGGGTTAATGACGTCGTGGAGTTGAACCAAATAAGTCAGCGGATGTTGGCGCAGATCAGTAGTGGTCAAGCCCT
TCGCATATAG

Upstream 100 bases:

>100_bases
GCGGCCTGATGTTCGCTGGCCACTCGGAGAATTTCAGCCAGATCAGTCGGGAATTCTATTTGCGCGGGCAGACCGTTTAT
GGGCTGACCAAGGAGAGGTG

Downstream 100 bases:

>100_bases
AGATCTCATTATGATGGGGGTCTATAAATTATTTTTCCGATAACCATCGGGCTATTGCATTTAATCGCTCAGCGCTGAGC
AACAAACTTTAGGAGTGGGT

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSKVRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMPRMDGLDFLEKLMRLRPMPVV
MVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYSELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLIA
IGASTGGTEAIRAVLQPLPPTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARSG
ANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAYTLAQNEASCVVFGMPREAIA
MGGVNDVVELNQISQRMLAQISSGQALRI

Sequences:

>Translated_349_residues
MSKVRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMPRMDGLDFLEKLMRLRPMPVV
MVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYSELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLIA
IGASTGGTEAIRAVLQPLPPTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARSG
ANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAYTLAQNEASCVVFGMPREAIA
MGGVNDVVELNQISQRMLAQISSGQALRI
>Mature_348_residues
SKVRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMPRMDGLDFLEKLMRLRPMPVVM
VSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYSELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLIAI
GASTGGTEAIRAVLQPLPPTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARSGA
NYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAYTLAQNEASCVVFGMPREAIAM
GGVNDVVELNQISQRMLAQISSGQALRI

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=349, Percent_Identity=84.2406876790831, Blast_Score=601, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 37969; Mature: 37838

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMP
CCCEEEEEECCHHHHHHHHHHHHHCCCCCEEHHHCCCCHHHHHHHHHCCCCEEEEEECCC
RMDGLDFLEKLMRLRPMPVVMVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYS
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEHHCCEEEECCCCCCHHHHHHHHH
ELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLIAIGASTGGTEAIRAVLQPLPP
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCC
TSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARSG
CCCEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCCEECCCCEEECCCCCHHHHHHCC
ANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAY
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHCCCE
TLAQNEASCVVFGMPREAIAMGGVNDVVELNQISQRMLAQISSGQALRI
EEECCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure 
SKVRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMP
CCEEEEEECCHHHHHHHHHHHHHCCCCCEEHHHCCCCHHHHHHHHHCCCCEEEEEECCC
RMDGLDFLEKLMRLRPMPVVMVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYS
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEHHCCEEEECCCCCCHHHHHHHHH
ELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLIAIGASTGGTEAIRAVLQPLPP
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCC
TSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARSG
CCCEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCCEECCCCEEECCCCCHHHHHHCC
ANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAY
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHCCCE
TLAQNEASCVVFGMPREAIAMGGVNDVVELNQISQRMLAQISSGQALRI
EEECCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA