Click here to switch to the map view.

The map label for this gene is prc

Identifier: 51596700

GI number: 51596700

Start: 2801394

End: 2803472

Strand: Reverse

Name: prc

Synonym: YPTB2376

Alternate gene names: 51596700

Gene position: 2803472-2801394 (Counterclockwise)

Preceding gene: 51596701

Following gene: 51596699

Centisome position: 59.09

GC content: 47.33

Gene sequence:

>2079_bases
ATGAACAAATTTGTCAGACTAGCAGCAATCGCAGGCTTGTTACTGGCTGGGGCGAGTTACGCAACCGATACAACGTATCG
AATTGATCAACTCCCTCAATTACGTCAGGAACCTGAGCATGCAACCGTGAGTGAGCGCGTAACATCGCGCTTTACTCGCT
CTCATTATCGCCAATTTGCATTGGACGATCAGTTTTCCGCCAAAATATTTGACCGCTACCTCAATATGCTGGATTACAGC
CATAACGTATTGTTGGCATCAGATGTGGCACAGTTCGCGGATAAAAAGTATTCGCTGGACAAAGAGTTAAAATCAGGTCA
ATTAGACACGCCTTTTGCCTTATTCAATCTGGCACAGAAACGCCGTTTTGAACGCTATCAATATGCGTTGTCAGTACTGG
ACCGGCCAATGGTCTTTACTGGTAACGATACGATTGATATTGATCGGGCCAAAGCGCCGTGGCCAAGCAGTGAAGCCGAA
CTGAATGCGCTTTGGGATGCAAAAGTAAAATACGACCAGCTTAATTTGAAGTTAGCGGGTAAAACGGATAAAGAGATCAA
AGAGACGCTGACGAAACGCTATCAATCAGCCATTAAGCGTTTGACGCAAAGCAACAGCGAAGATGTTTTCCAGTTGATCA
TGAACGCCTTTGCTCGCGAGATTGACCCGCATACCAACTACCTTTCTCCACGTAATACTGAACAGTTCAATACCGAGATG
AGTTTGTCTCTGGAAGGTATTGGCGCGGTATTACAAATGGATGATGATTATACACTCATCAATTCTATGGTCCCTGGTGG
TCCGGCGGCGAAGAGTAAAACGATAGCGGTGGGTGATCGGGTTATCGGTGTAGGGCAGGCGGGTAAGCCAATGGTTGATG
TTATAGGCTGGCGTCTTGACGATGTGGTTGCTCTGATCAAAGGGCCAAAGGGCAGTAAAGTACGGTTAGAAATTTTACCT
GCGGGTAAAGGGACTAAACCTCGTACTGTAACCTTGACCCGCGAGCGCATTCGTCTGGAAGATCGCGCGGTGAAAATGTC
GGTGAAAACCATCGGTAAAGAACGCGTAGGTGTGTTGGATATTCCGGGTTTCTATGTTGGCCTGACCGAAGACGTTAAGG
TGCAATTACAGAAGCTTGAGAAACAGAATGTCAGCAGCATCATCATTGATCTACGCAGTAATGGTGGCGGCGCATTAACC
GAAGCTGTTTCACTTTCTGGTTTGTTCATTCCGAGTGGGCCAGTGGTTCAGGTGCGGGATAACAATGGCAAAGTGCGTGA
AGACAGTGATACTGACGGTGTGGTGTATTACAAAGGCCCGCTGGTGGTATTGGTTGATCGCTACAGTGCGTCGGCATCTG
AGATTTTTGCCGCCGCTATGCAGGATTATGGCCGTGCATTAATTGTCGGTGAGCCAACCTTCGGCAAAGGCACTGTTCAG
CAATATCGCTCACTTAATCGTATATACGATCAAATGCTACGCCCTGAGTGGCCAGCGTTAGGCTCACTGCAATACACCAT
TCAGAAGTTTTATCGGGTGGATGGCGGTAGTACGCAGCGCAAAGGTGTGACTCCGGATATCGTGATGCCTACAGGGGTTG
ATCCGGCGGAAACGGGTGAAAACTTCGAAGATAATGCTTTGCCATGGGACAGGATCAATGCTGCCAGTTATACCAAAACG
GGTGATTTGAAACCCTGGGAGCCTGAGTTACTGAAGAATCATGCTGAGCGTATCGCCGCTAATCCTGAATTCCAGTATAT
TCAGAAAGATATTGAGCGTTATAAGGCTTTGAAAGATAAGCGTAACATTGTCTCTCTCAATTACGCCCAGCGTGAAAAAG
AGAACCGTGATGATGATATGACGCGCTTGACTCGTTTAAATGAACGCTTCATCCGTGAAGGTAAGAAGCCTCTGAAATCG
TTGGATGATTTACCAAAAGATTATCAGGAGCCAGACCCTTATTTGGATGAAACGGTGAATATTGCCTTGGATTTAGCCCA
CCAGGAAAAAGCTCAGCCACAGATTGCATCTCGCCCTGTCGCTGCTGCTACCGCTACCGCTGGGGCAACGGTAAAATAA

Upstream 100 bases:

>100_bases
GAAATCGCTAAAGATGGCGTACGGGTGCAGCTATCTTCCGGTCTGGCGATGATTGTGCGCGCAGAACACTTGCAGTTCTG
ATACGGAGGCCAACCTAGGC

Downstream 100 bases:

>100_bases
ATCTGCAAATAATATGAAGAATCCGGGTCTTATTGGACTCGGATTTTTTTTTGCTTTTTTTCAGGTGCATGACGGATGAA
CAGGCTGCTTAACCCTTGTT

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MNKFVRLAAIAGLLLAGASYATDTTYRIDQLPQLRQEPEHATVSERVTSRFTRSHYRQFALDDQFSAKIFDRYLNMLDYS
HNVLLASDVAQFADKKYSLDKELKSGQLDTPFALFNLAQKRRFERYQYALSVLDRPMVFTGNDTIDIDRAKAPWPSSEAE
LNALWDAKVKYDQLNLKLAGKTDKEIKETLTKRYQSAIKRLTQSNSEDVFQLIMNAFAREIDPHTNYLSPRNTEQFNTEM
SLSLEGIGAVLQMDDDYTLINSMVPGGPAAKSKTIAVGDRVIGVGQAGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILP
AGKGTKPRTVTLTRERIRLEDRAVKMSVKTIGKERVGVLDIPGFYVGLTEDVKVQLQKLEKQNVSSIIIDLRSNGGGALT
EAVSLSGLFIPSGPVVQVRDNNGKVREDSDTDGVVYYKGPLVVLVDRYSASASEIFAAAMQDYGRALIVGEPTFGKGTVQ
QYRSLNRIYDQMLRPEWPALGSLQYTIQKFYRVDGGSTQRKGVTPDIVMPTGVDPAETGENFEDNALPWDRINAASYTKT
GDLKPWEPELLKNHAERIAANPEFQYIQKDIERYKALKDKRNIVSLNYAQREKENRDDDMTRLTRLNERFIREGKKPLKS
LDDLPKDYQEPDPYLDETVNIALDLAHQEKAQPQIASRPVAAATATAGATVK

Sequences:

>Translated_692_residues
MNKFVRLAAIAGLLLAGASYATDTTYRIDQLPQLRQEPEHATVSERVTSRFTRSHYRQFALDDQFSAKIFDRYLNMLDYS
HNVLLASDVAQFADKKYSLDKELKSGQLDTPFALFNLAQKRRFERYQYALSVLDRPMVFTGNDTIDIDRAKAPWPSSEAE
LNALWDAKVKYDQLNLKLAGKTDKEIKETLTKRYQSAIKRLTQSNSEDVFQLIMNAFAREIDPHTNYLSPRNTEQFNTEM
SLSLEGIGAVLQMDDDYTLINSMVPGGPAAKSKTIAVGDRVIGVGQAGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILP
AGKGTKPRTVTLTRERIRLEDRAVKMSVKTIGKERVGVLDIPGFYVGLTEDVKVQLQKLEKQNVSSIIIDLRSNGGGALT
EAVSLSGLFIPSGPVVQVRDNNGKVREDSDTDGVVYYKGPLVVLVDRYSASASEIFAAAMQDYGRALIVGEPTFGKGTVQ
QYRSLNRIYDQMLRPEWPALGSLQYTIQKFYRVDGGSTQRKGVTPDIVMPTGVDPAETGENFEDNALPWDRINAASYTKT
GDLKPWEPELLKNHAERIAANPEFQYIQKDIERYKALKDKRNIVSLNYAQREKENRDDDMTRLTRLNERFIREGKKPLKS
LDDLPKDYQEPDPYLDETVNIALDLAHQEKAQPQIASRPVAAATATAGATVK
>Mature_692_residues
MNKFVRLAAIAGLLLAGASYATDTTYRIDQLPQLRQEPEHATVSERVTSRFTRSHYRQFALDDQFSAKIFDRYLNMLDYS
HNVLLASDVAQFADKKYSLDKELKSGQLDTPFALFNLAQKRRFERYQYALSVLDRPMVFTGNDTIDIDRAKAPWPSSEAE
LNALWDAKVKYDQLNLKLAGKTDKEIKETLTKRYQSAIKRLTQSNSEDVFQLIMNAFAREIDPHTNYLSPRNTEQFNTEM
SLSLEGIGAVLQMDDDYTLINSMVPGGPAAKSKTIAVGDRVIGVGQAGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILP
AGKGTKPRTVTLTRERIRLEDRAVKMSVKTIGKERVGVLDIPGFYVGLTEDVKVQLQKLEKQNVSSIIIDLRSNGGGALT
EAVSLSGLFIPSGPVVQVRDNNGKVREDSDTDGVVYYKGPLVVLVDRYSASASEIFAAAMQDYGRALIVGEPTFGKGTVQ
QYRSLNRIYDQMLRPEWPALGSLQYTIQKFYRVDGGSTQRKGVTPDIVMPTGVDPAETGENFEDNALPWDRINAASYTKT
GDLKPWEPELLKNHAERIAANPEFQYIQKDIERYKALKDKRNIVSLNYAQREKENRDDDMTRLTRLNERFIREGKKPLKS
LDDLPKDYQEPDPYLDETVNIALDLAHQEKAQPQIASRPVAAATATAGATVK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=681, Percent_Identity=81.6446402349486, Blast_Score=1153, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 77575; Mature: 77575

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFVRLAAIAGLLLAGASYATDTTYRIDQLPQLRQEPEHATVSERVTSRFTRSHYRQFA
CCHHHHHHHHHHHHHHCCCCCCCCCEEHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
LDDQFSAKIFDRYLNMLDYSHNVLLASDVAQFADKKYSLDKELKSGQLDTPFALFNLAQK
CCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHH
RRFERYQYALSVLDRPMVFTGNDTIDIDRAKAPWPSSEAELNALWDAKVKYDQLNLKLAG
HHHHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCCCCCCCEEECCEEEEEEEEEEECC
KTDKEIKETLTKRYQSAIKRLTQSNSEDVFQLIMNAFAREIDPHTNYLSPRNTEQFNTEM
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCEE
SLSLEGIGAVLQMDDDYTLINSMVPGGPAAKSKTIAVGDRVIGVGQAGKPMVDVIGWRLD
EEEECCCCEEEEECCCHHHHHHCCCCCCCCCCCEEEECCEEEECCCCCCCHHHHHCCCHH
DVVALIKGPKGSKVRLEILPAGKGTKPRTVTLTRERIRLEDRAVKMSVKTIGKERVGVLD
HHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEE
IPGFYVGLTEDVKVQLQKLEKQNVSSIIIDLRSNGGGALTEAVSLSGLFIPSGPVVQVRD
CCCEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCEEEECCCCEEEEEC
NNGKVREDSDTDGVVYYKGPLVVLVDRYSASASEIFAAAMQDYGRALIVGEPTFGKGTVQ
CCCCEECCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHH
QYRSLNRIYDQMLRPEWPALGSLQYTIQKFYRVDGGSTQRKGVTPDIVMPTGVDPAETGE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHCCC
NFEDNALPWDRINAASYTKTGDLKPWEPELLKNHAERIAANPEFQYIQKDIERYKALKDK
CCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
RNIVSLNYAQREKENRDDDMTRLTRLNERFIREGKKPLKSLDDLPKDYQEPDPYLDETVN
CCEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHCCCCCCHHHHHH
IALDLAHQEKAQPQIASRPVAAATATAGATVK
HEEEEHHHHHCCCHHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MNKFVRLAAIAGLLLAGASYATDTTYRIDQLPQLRQEPEHATVSERVTSRFTRSHYRQFA
CCHHHHHHHHHHHHHHCCCCCCCCCEEHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
LDDQFSAKIFDRYLNMLDYSHNVLLASDVAQFADKKYSLDKELKSGQLDTPFALFNLAQK
CCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHH
RRFERYQYALSVLDRPMVFTGNDTIDIDRAKAPWPSSEAELNALWDAKVKYDQLNLKLAG
HHHHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCCCCCCCEEECCEEEEEEEEEEECC
KTDKEIKETLTKRYQSAIKRLTQSNSEDVFQLIMNAFAREIDPHTNYLSPRNTEQFNTEM
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCEE
SLSLEGIGAVLQMDDDYTLINSMVPGGPAAKSKTIAVGDRVIGVGQAGKPMVDVIGWRLD
EEEECCCCEEEEECCCHHHHHHCCCCCCCCCCCEEEECCEEEECCCCCCCHHHHHCCCHH
DVVALIKGPKGSKVRLEILPAGKGTKPRTVTLTRERIRLEDRAVKMSVKTIGKERVGVLD
HHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEE
IPGFYVGLTEDVKVQLQKLEKQNVSSIIIDLRSNGGGALTEAVSLSGLFIPSGPVVQVRD
CCCEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCEEEECCCCEEEEEC
NNGKVREDSDTDGVVYYKGPLVVLVDRYSASASEIFAAAMQDYGRALIVGEPTFGKGTVQ
CCCCEECCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHH
QYRSLNRIYDQMLRPEWPALGSLQYTIQKFYRVDGGSTQRKGVTPDIVMPTGVDPAETGE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHCCC
NFEDNALPWDRINAASYTKTGDLKPWEPELLKNHAERIAANPEFQYIQKDIERYKALKDK
CCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
RNIVSLNYAQREKENRDDDMTRLTRLNERFIREGKKPLKSLDDLPKDYQEPDPYLDETVN
CCEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHCCCCCCHHHHHH
IALDLAHQEKAQPQIASRPVAAATATAGATVK
HEEEEHHHHHCCCHHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]