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The map label for this gene is yebQ [H]

Identifier: 51596693

GI number: 51596693

Start: 2791758

End: 2793125

Strand: Direct

Name: yebQ [H]

Synonym: YPTB2369

Alternate gene names: 51596693

Gene position: 2791758-2793125 (Clockwise)

Preceding gene: 51596689

Following gene: 51596703

Centisome position: 58.84

GC content: 51.17

Gene sequence:

>1368_bases
ATGAACCCATCAACAAGTGATGGCTTACCTGTACCTCAACGCTATGCCGCGATACTGGTTATTGCTTTAGGTATTATGAT
GGCGGTATTGGACGGCACTATTGCCAACGTGGCATTACCGACTATCGCACGTGACCTCAATACCAGCCCAGCGACATCTA
TCTGGGTTGTCAATGCTTATCAGCTCGCCATCACCATCTCACTGCTTTCCATGGCGTCATTGGGCGATATCATTGGTTAC
CGGCGGGTTTATCAAGCTGGCTTACTGATATTCAGCGTGACCTCACTGTTTTGTGCTCTGTCCGATTCGTTATGGACCCT
GACGTTTGCCCGTGTGCTACAAGGGTTTGGCGCGGCGGCATTGATGAGCGTCAATACCGCCCTGATTCGTATCATTTATC
CTCGAGCCCAACTTGGTCGAGGTATTGGTATCAATACCTTGATTGTTGCTGTGTCTTCAGCCGCGGGGCCCAGTATTGCC
GCTGCCGTGTTGTCTGTCGCCTCTTGGCAATGGCTGTTCGCCCTCAACGTGCCAATTGGGCTATTAGCGTGGTGTTTAGG
TATAAAATTCCTACCCGCCAATAATACGAAAAGCAACGGCAATCGCTTTGATATCACCAGTTGTGTTCTGAATGCGCTGA
CATTTGGCTTATTGATCATCGCAATCAGTGGTTTTTCCCAAGGGCAAAGCCCGGCAGTGATTGCTGCTCAAGTGGTTGCC
CTATTACTGATTGGTTTCTTCTTTGTGCGTCGTCAACTCACGCAATCCTTCCCACTGCTCCCCGTGGATTTACTGCGTAT
TCCTATTTTCGCGTTGTCGATTGGCACTTCAATTTTTTCTTTTGCCGCTCAAATGCTGGCAATGGTGTCGCTTCCCTTCT
TTTTACAGACCGTATTGGGCCGCGACGAAGTGGCAACCGGGCTACTGTTGACTCCATGGCCGTTGGCCACCATGGTCATT
GCTCCGATCGCGGGGCGTTTGGTTGAGCGCTATCATGCAGGTTTATTAGGTGGGATTGGTCTGGCTGTTTTTGCCAGTGG
TCTATTCTTGCTGGCGGTGTTACCCGCCAACCCCAGCGACGTAGATATTATCTGGCGGATGATACTGTGTGGCGCGGGTT
TTGGGCTGTTCCAGACCCCAAATAATCATACGATCATTTCTGCCGCTCCACAGCATCGTAGCGGCGGAGCCAGTGGCATG
TTGGGGACCGCCCGCTTGCTAGGACAGACCTCAGGTGCTGCCTTGGTTGCGCTAATGTTCAATATGTTCTCAACCAACGG
CACCCACGCCTCCTTGATACTGGCTGGCTGTTTTGCCAGTATCGCGGCACTGGTGAGTCTCTTACGTGTAACACAAAAAA
GTCATTAG

Upstream 100 bases:

>100_bases
TATACTTACAATTAATCTGATGTGTAAGGATGCAATCAGGGGCAATAATCGTTAGCATATCAATACTCACCTATTTTATT
ACTTTTACAGATACGCACCT

Downstream 100 bases:

>100_bases
GCTCTTGGGGGAAGCCTGAATATTGGCTTCCCCCCGGCAAGACGATCACTGATTTATTGTAGTGGCTGCTGCCCTTCAAT
GGGTGAGCCAAAATCATCAA

Product: major facilitator superfamily multidrug efflux transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNPSTSDGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITISLLSMASLGDIIGY
RRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNTALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIA
AAVLSVASWQWLFALNVPIGLLAWCLGIKFLPANNTKSNGNRFDITSCVLNALTFGLLIIAISGFSQGQSPAVIAAQVVA
LLLIGFFFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVATGLLLTPWPLATMVI
APIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSDVDIIWRMILCGAGFGLFQTPNNHTIISAAPQHRSGGASGM
LGTARLLGQTSGAALVALMFNMFSTNGTHASLILAGCFASIAALVSLLRVTQKSH

Sequences:

>Translated_455_residues
MNPSTSDGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITISLLSMASLGDIIGY
RRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNTALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIA
AAVLSVASWQWLFALNVPIGLLAWCLGIKFLPANNTKSNGNRFDITSCVLNALTFGLLIIAISGFSQGQSPAVIAAQVVA
LLLIGFFFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVATGLLLTPWPLATMVI
APIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSDVDIIWRMILCGAGFGLFQTPNNHTIISAAPQHRSGGASGM
LGTARLLGQTSGAALVALMFNMFSTNGTHASLILAGCFASIAALVSLLRVTQKSH
>Mature_455_residues
MNPSTSDGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITISLLSMASLGDIIGY
RRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNTALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIA
AAVLSVASWQWLFALNVPIGLLAWCLGIKFLPANNTKSNGNRFDITSCVLNALTFGLLIIAISGFSQGQSPAVIAAQVVA
LLLIGFFFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVATGLLLTPWPLATMVI
APIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSDVDIIWRMILCGAGFGLFQTPNNHTIISAAPQHRSGGASGM
LGTARLLGQTSGAALVALMFNMFSTNGTHASLILAGCFASIAALVSLLRVTQKSH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=452, Percent_Identity=69.6902654867257, Blast_Score=624, Evalue=1e-180,
Organism=Escherichia coli, GI1788392, Length=328, Percent_Identity=30.7926829268293, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790195, Length=325, Percent_Identity=30.1538461538462, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789042, Length=409, Percent_Identity=27.1393643031785, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788710, Length=406, Percent_Identity=25.8620689655172, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325455, Length=142, Percent_Identity=32.3943661971831, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319770, Length=317, Percent_Identity=23.9747634069401, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47781; Mature: 47781

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPSTSDGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEHH
QLAITISLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LMSVNTALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIG
HHHHHHHHHHEEECHHHHCCCCCHHHHHHEECCCCCHHHHHHHHHHHCCCEEEEECCCHH
LLAWCLGIKFLPANNTKSNGNRFDITSCVLNALTFGLLIIAISGFSQGQSPAVIAAQVVA
HHHHHHCCEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLLIGFFFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDEVATGLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSD
CHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCH
VDIIWRMILCGAGFGLFQTPNNHTIISAAPQHRSGGASGMLGTARLLGQTSGAALVALMF
HHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHH
NMFSTNGTHASLILAGCFASIAALVSLLRVTQKSH
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPSTSDGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEHH
QLAITISLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LMSVNTALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIG
HHHHHHHHHHEEECHHHHCCCCCHHHHHHEECCCCCHHHHHHHHHHHCCCEEEEECCCHH
LLAWCLGIKFLPANNTKSNGNRFDITSCVLNALTFGLLIIAISGFSQGQSPAVIAAQVVA
HHHHHHCCEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLLIGFFFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDEVATGLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSD
CHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCH
VDIIWRMILCGAGFGLFQTPNNHTIISAAPQHRSGGASGMLGTARLLGQTSGAALVALMF
HHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHH
NMFSTNGTHASLILAGCFASIAALVSLLRVTQKSH
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]