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The map label for this gene is lsrR [H]

Identifier: 51596567

GI number: 51596567

Start: 2649436

End: 2650392

Strand: Reverse

Name: lsrR [H]

Synonym: YPTB2243

Alternate gene names: 51596567

Gene position: 2650392-2649436 (Counterclockwise)

Preceding gene: 51596569

Following gene: 161760572

Centisome position: 55.86

GC content: 53.19

Gene sequence:

>957_bases
ATGCATAAGAGTGATAAGAAACTGGATCAGGCGGCCAGAGCGGCCTGGATGTATTATGTTGCTGGGCAAACTCAGCATGA
AATTGCCGAGGCGTTAGGCGTCTCTCGGCAGGTTGCACAGCGGTTGGTGGCTTGCGCCATTGATAATGGATTGGTCAGTG
TCAATATCACGCACCCTGTGGCTCGCTGTATGGCGCTGGCCGAGCAATTACAACAACGCTATGGTTTACACCGTTGCCAG
GTTGTCCCTAGCCAAGGCATGGACAACGCGGGGGTTCAACGTGCAATTGCCGTGGCGGGGGCCGAGGTGATGGCGCAGTT
TCTACGACAAGAGCAACCCTTAGTTATTGGCGTCGGTTCAGGGCGCAGTTTAAAGGCCGCCATCGATGAGTTGCCTGATG
TTGAACGGCCGCAACATAGCTGTGTATCATTGATAGGGGCCATTGCCGCTGACGGCTCTTGCACCCGTTACGACGTCCCG
TTGTGGATGGCTGAGAAAACCCAAGGCCGCTATTTTATCCTGCCAGCCCCTTTATTTGCTGACAGCGCCGCTGATCGTGA
CCTGTGGTGTAACCATCGCATTTATCGCACTGTCACCGAAAAAGCAGCGCAGGCCGATGTCACCTTTATCGGTATCGGTT
CGATTGGCTACCATTGCCCGTTACACAAAGATGGTTTTATTTCGGCGCAAGATGTGGATGCCTTGCTCGCATCGCATGTG
GTCGCGGAGATGCTGGGTAATTTTATTGATGCGGATGGGCAACCCGTCCCGTACGCGTTGGATCAATGCTTAACCAGCGT
GAAATTACGTATTCAGCCGGAAAAACCCGTGATCGCTATTGCCGGCGGGAAAGAAAAGCATCAGGCGATTAAAGCGGCTT
TGAAGGGGCAGTGGCTGAATGGTTTAGTGACTGATGAAGAGAGTGCCATGGTTCTGCTGGCGGAAGAAAAGGCATAA

Upstream 100 bases:

>100_bases
AGCTTTAGCTCACATAAACGTGCGTAGGGATAAAAATCTGCGAAATAGCGACGTAATATGACTAATATTGTTACTTCAAA
AAATAATGCGCAGATAACCC

Downstream 100 bases:

>100_bases
AAAAGCGCGCCGGTTGGCGCGCAATCATCACATGGCTTTCGGGTAAAATGAGGGTAATACGAGGCCATCTTTTTACTCGC
TCATTAGGGTGACACCCCTA

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MHKSDKKLDQAARAAWMYYVAGQTQHEIAEALGVSRQVAQRLVACAIDNGLVSVNITHPVARCMALAEQLQQRYGLHRCQ
VVPSQGMDNAGVQRAIAVAGAEVMAQFLRQEQPLVIGVGSGRSLKAAIDELPDVERPQHSCVSLIGAIAADGSCTRYDVP
LWMAEKTQGRYFILPAPLFADSAADRDLWCNHRIYRTVTEKAAQADVTFIGIGSIGYHCPLHKDGFISAQDVDALLASHV
VAEMLGNFIDADGQPVPYALDQCLTSVKLRIQPEKPVIAIAGGKEKHQAIKAALKGQWLNGLVTDEESAMVLLAEEKA

Sequences:

>Translated_318_residues
MHKSDKKLDQAARAAWMYYVAGQTQHEIAEALGVSRQVAQRLVACAIDNGLVSVNITHPVARCMALAEQLQQRYGLHRCQ
VVPSQGMDNAGVQRAIAVAGAEVMAQFLRQEQPLVIGVGSGRSLKAAIDELPDVERPQHSCVSLIGAIAADGSCTRYDVP
LWMAEKTQGRYFILPAPLFADSAADRDLWCNHRIYRTVTEKAAQADVTFIGIGSIGYHCPLHKDGFISAQDVDALLASHV
VAEMLGNFIDADGQPVPYALDQCLTSVKLRIQPEKPVIAIAGGKEKHQAIKAALKGQWLNGLVTDEESAMVLLAEEKA
>Mature_318_residues
MHKSDKKLDQAARAAWMYYVAGQTQHEIAEALGVSRQVAQRLVACAIDNGLVSVNITHPVARCMALAEQLQQRYGLHRCQ
VVPSQGMDNAGVQRAIAVAGAEVMAQFLRQEQPLVIGVGSGRSLKAAIDELPDVERPQHSCVSLIGAIAADGSCTRYDVP
LWMAEKTQGRYFILPAPLFADSAADRDLWCNHRIYRTVTEKAAQADVTFIGIGSIGYHCPLHKDGFISAQDVDALLASHV
VAEMLGNFIDADGQPVPYALDQCLTSVKLRIQPEKPVIAIAGGKEKHQAIKAALKGQWLNGLVTDEESAMVLLAEEKA

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=313, Percent_Identity=30.3514376996805, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082414, Length=314, Percent_Identity=25.4777070063694, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 34431; Mature: 34431

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKSDKKLDQAARAAWMYYVAGQTQHEIAEALGVSRQVAQRLVACAIDNGLVSVNITHPV
CCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHCHHHHHHHHHHHHHHCCCEEEEEEHHHH
ARCMALAEQLQQRYGLHRCQVVPSQGMDNAGVQRAIAVAGAEVMAQFLRQEQPLVIGVGS
HHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GRSLKAAIDELPDVERPQHSCVSLIGAIAADGSCTRYDVPLWMAEKTQGRYFILPAPLFA
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCEEEEECCHHC
DSAADRDLWCNHRIYRTVTEKAAQADVTFIGIGSIGYHCPLHKDGFISAQDVDALLASHV
CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
VAEMLGNFIDADGQPVPYALDQCLTSVKLRIQPEKPVIAIAGGKEKHQAIKAALKGQWLN
HHHHHHHHHCCCCCCCCHHHHHHHHHCEEEEECCCCEEEEECCCHHHHHHHHHHCCHHHC
GLVTDEESAMVLLAEEKA
CEEECCCCEEEEEEECCC
>Mature Secondary Structure
MHKSDKKLDQAARAAWMYYVAGQTQHEIAEALGVSRQVAQRLVACAIDNGLVSVNITHPV
CCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHCHHHHHHHHHHHHHHCCCEEEEEEHHHH
ARCMALAEQLQQRYGLHRCQVVPSQGMDNAGVQRAIAVAGAEVMAQFLRQEQPLVIGVGS
HHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GRSLKAAIDELPDVERPQHSCVSLIGAIAADGSCTRYDVPLWMAEKTQGRYFILPAPLFA
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCEEEEECCHHC
DSAADRDLWCNHRIYRTVTEKAAQADVTFIGIGSIGYHCPLHKDGFISAQDVDALLASHV
CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
VAEMLGNFIDADGQPVPYALDQCLTSVKLRIQPEKPVIAIAGGKEKHQAIKAALKGQWLN
HHHHHHHHHCCCCCCCCHHHHHHHHHCEEEEECCCCEEEEECCCHHHHHHHHHHCCHHHC
GLVTDEESAMVLLAEEKA
CEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]