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The map label for this gene is amn

Identifier: 51596535

GI number: 51596535

Start: 2604403

End: 2605893

Strand: Reverse

Name: amn

Synonym: YPTB2211

Alternate gene names: 51596535

Gene position: 2605893-2604403 (Counterclockwise)

Preceding gene: 51596539

Following gene: 51596531

Centisome position: 54.92

GC content: 49.77

Gene sequence:

>1491_bases
TTGAATAAATTACAAGATACAGGCTCTCTCGCAGTTGTTGAGGCCATTGATAAGCTGGAAATGCTCTATGATGCAGCGTT
AGCCGCTTTACGGGATGCGATCAGCGCATTTATTCGTGATGGTTCTTTGCCTAATGCAGCGGAAAGATCCAAGGGGTTAT
TTAGCTACCCACAGCTTAGTGTCCGATGGGATGGTAAATTTAGCGATCATCACCGCACGCGTGCATACGGGCGCTTTTCC
CGGGCAGGGCAATACAGCACCACAATCACTCGACCCGCACTGTTCAGGGAATATCTGACCGAGCAAATGACGCTGCTTGA
AAGTGAGTATGGCGCGGTATTTGAAGTGACACCGTCACAACAAGAGATGCCTTATCCGTTTGTTATCGATGGTTCAGACC
TGATCCTTGATCGGTCAATGACCGCAGGCCTTGCCCAGCACTTCCCGACGACAGATCTGGCTAAAATCGGTGATGGCATC
ACCGACGGAATTGAAACGATAGCGCTTGGCACGGCATCACTTGGCAGCGCAGTAAGTGATCTACCGTTGTCTCACTTTGA
TGCGCTGCGCACTGATTTTTCCCTCGCACGGTTAAAACACTATACCGGTACGCCAGCCGAAGACATTCAACCGTATATTC
TTTTTACCAATTACAGCCGTTATGTTGATGAATTTGTCCGTTGGGCGGGTGAGCAAATTTTGGATCCAAACAGCCCCTAT
AAAGCACTCTCCTGCGCAGGCGGTAGTTACATCACGGCAGAGAATGCCGATCCGGAAAAAACCCTTTCTGACCTGGCGTG
GAAAAAACATCAGATGCCAGCCTATCACCTGATAGCCAAAAATGGGCAGGGCATCACATTGGTTAATATTGGTGTCGGCC
CCTCCAATGCCAAAACAATTTGTGACCACTTGGCGGTATTGAGGCCACATGTTTGGTTGATGATTGGCCACTGTGGTGGC
CTGCGAGAAAGCCAATCCATTGGTGATTATGTGCTGGCACATGCGTACTTGCGTGATGACCATGTTCTGGATGCGGTATT
ACCGCCCGATATTCCGATCCCTAGCATTGCCGAGATACAACGCGCCTTGTACGACGCGACCAAAGCCGTTAGTGGTATGC
CAGGCGTTGAGGTAAAACAACGTCTGCGCACCGGGACTGTCGTTACCTCTGATGATCGTAACTGGGAATTACGTTTCTCC
GCCTCATCGCTACGTTTTAGTTTAAGTCGCGCGGTGGCTGTTGATATGGAAAGCGCCACTATCGCTGCTCAAGGCTATCG
CTTCCGGGTGCCTTACGGGACCTTGCTTTGTGTTTCCGACAAGCCATTACATGGCGAAATTAAACTGCCGGGGCAGGCCA
ACCATTTTTATGAGGGTGCTATTTCTGAGCATTTGCAGATTGGTATTCGGGCAATCGATTTGCTACGGGCAGAAGGTGAC
CAATTACACTCTCGTAAATTACGTACCTTTAATGAGCCACCGTTCCGTTAA

Upstream 100 bases:

>100_bases
CAAAAGGTCCTCCTGTTTTCAGGAAAAGGCTGGATTTGCTGCGCAATAAATAGCACTGTGTTGGTCAATAATCGCTGCTC
TTGTGTTTAAAGGAGGTACT

Downstream 100 bases:

>100_bases
AAAGAATAGATTGAAAAACAACGCAGGCGGATGATGATCACCGCCTGCGTATTGAATTGAGAGAGCTTACATTAATCAGC
GAATGCCGGTGCCTATCCTG

Product: AMP nucleosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MNKLQDTGSLAVVEAIDKLEMLYDAALAALRDAISAFIRDGSLPNAAERSKGLFSYPQLSVRWDGKFSDHHRTRAYGRFS
RAGQYSTTITRPALFREYLTEQMTLLESEYGAVFEVTPSQQEMPYPFVIDGSDLILDRSMTAGLAQHFPTTDLAKIGDGI
TDGIETIALGTASLGSAVSDLPLSHFDALRTDFSLARLKHYTGTPAEDIQPYILFTNYSRYVDEFVRWAGEQILDPNSPY
KALSCAGGSYITAENADPEKTLSDLAWKKHQMPAYHLIAKNGQGITLVNIGVGPSNAKTICDHLAVLRPHVWLMIGHCGG
LRESQSIGDYVLAHAYLRDDHVLDAVLPPDIPIPSIAEIQRALYDATKAVSGMPGVEVKQRLRTGTVVTSDDRNWELRFS
ASSLRFSLSRAVAVDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANHFYEGAISEHLQIGIRAIDLLRAEGD
QLHSRKLRTFNEPPFR

Sequences:

>Translated_496_residues
MNKLQDTGSLAVVEAIDKLEMLYDAALAALRDAISAFIRDGSLPNAAERSKGLFSYPQLSVRWDGKFSDHHRTRAYGRFS
RAGQYSTTITRPALFREYLTEQMTLLESEYGAVFEVTPSQQEMPYPFVIDGSDLILDRSMTAGLAQHFPTTDLAKIGDGI
TDGIETIALGTASLGSAVSDLPLSHFDALRTDFSLARLKHYTGTPAEDIQPYILFTNYSRYVDEFVRWAGEQILDPNSPY
KALSCAGGSYITAENADPEKTLSDLAWKKHQMPAYHLIAKNGQGITLVNIGVGPSNAKTICDHLAVLRPHVWLMIGHCGG
LRESQSIGDYVLAHAYLRDDHVLDAVLPPDIPIPSIAEIQRALYDATKAVSGMPGVEVKQRLRTGTVVTSDDRNWELRFS
ASSLRFSLSRAVAVDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANHFYEGAISEHLQIGIRAIDLLRAEGD
QLHSRKLRTFNEPPFR
>Mature_496_residues
MNKLQDTGSLAVVEAIDKLEMLYDAALAALRDAISAFIRDGSLPNAAERSKGLFSYPQLSVRWDGKFSDHHRTRAYGRFS
RAGQYSTTITRPALFREYLTEQMTLLESEYGAVFEVTPSQQEMPYPFVIDGSDLILDRSMTAGLAQHFPTTDLAKIGDGI
TDGIETIALGTASLGSAVSDLPLSHFDALRTDFSLARLKHYTGTPAEDIQPYILFTNYSRYVDEFVRWAGEQILDPNSPY
KALSCAGGSYITAENADPEKTLSDLAWKKHQMPAYHLIAKNGQGITLVNIGVGPSNAKTICDHLAVLRPHVWLMIGHCGG
LRESQSIGDYVLAHAYLRDDHVLDAVLPPDIPIPSIAEIQRALYDATKAVSGMPGVEVKQRLRTGTVVTSDDRNWELRFS
ASSLRFSLSRAVAVDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANHFYEGAISEHLQIGIRAIDLLRAEGD
QLHSRKLRTFNEPPFR

Specific function: Involved in regulation of AMP concentrations [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788293, Length=494, Percent_Identity=74.2914979757085, Blast_Score=764, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011271
- InterPro:   IPR018953
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF10423 AMNp_N; PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.4 [H]

Molecular weight: Translated: 54774; Mature: 54774

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLQDTGSLAVVEAIDKLEMLYDAALAALRDAISAFIRDGSLPNAAERSKGLFSYPQLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEE
VRWDGKFSDHHRTRAYGRFSRAGQYSTTITRPALFREYLTEQMTLLESEYGAVFEVTPSQ
EEECCCCCCCHHHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
QEMPYPFVIDGSDLILDRSMTAGLAQHFPTTDLAKIGDGITDGIETIALGTASLGSAVSD
CCCCCCEEECCCCEEEECHHHHHHHHHCCCCHHHHHCCCHHHHHHHHEECCHHHHHHHHH
LPLSHFDALRTDFSLARLKHYTGTPAEDIQPYILFTNYSRYVDEFVRWAGEQILDPNSPY
CCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECHHHHHHHHHHHCCHHHCCCCCCC
KALSCAGGSYITAENADPEKTLSDLAWKKHQMPAYHLIAKNGQGITLVNIGVGPSNAKTI
CCEEECCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCCCHHHH
CDHLAVLRPHVWLMIGHCGGLRESQSIGDYVLAHAYLRDDHVLDAVLPPDIPIPSIAEIQ
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHH
RALYDATKAVSGMPGVEVKQRLRTGTVVTSDDRNWELRFSASSLRFSLSRAVAVDMESAT
HHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCEEEEEEHHHHHHHHHHEEEEECCCCE
IAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANHFYEGAISEHLQIGIRAIDLLRAEGD
EEECCEEEECCCCEEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
QLHSRKLRTFNEPPFR
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNKLQDTGSLAVVEAIDKLEMLYDAALAALRDAISAFIRDGSLPNAAERSKGLFSYPQLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEE
VRWDGKFSDHHRTRAYGRFSRAGQYSTTITRPALFREYLTEQMTLLESEYGAVFEVTPSQ
EEECCCCCCCHHHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
QEMPYPFVIDGSDLILDRSMTAGLAQHFPTTDLAKIGDGITDGIETIALGTASLGSAVSD
CCCCCCEEECCCCEEEECHHHHHHHHHCCCCHHHHHCCCHHHHHHHHEECCHHHHHHHHH
LPLSHFDALRTDFSLARLKHYTGTPAEDIQPYILFTNYSRYVDEFVRWAGEQILDPNSPY
CCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECHHHHHHHHHHHCCHHHCCCCCCC
KALSCAGGSYITAENADPEKTLSDLAWKKHQMPAYHLIAKNGQGITLVNIGVGPSNAKTI
CCEEECCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCCCHHHH
CDHLAVLRPHVWLMIGHCGGLRESQSIGDYVLAHAYLRDDHVLDAVLPPDIPIPSIAEIQ
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHH
RALYDATKAVSGMPGVEVKQRLRTGTVVTSDDRNWELRFSASSLRFSLSRAVAVDMESAT
HHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCEEEEEEHHHHHHHHHHEEEEECCCCE
IAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANHFYEGAISEHLQIGIRAIDLLRAEGD
EEECCEEEECCCCEEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
QLHSRKLRTFNEPPFR
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]