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The map label for this gene is ynfM [H]

Identifier: 51596514

GI number: 51596514

Start: 2576875

End: 2578173

Strand: Reverse

Name: ynfM [H]

Synonym: YPTB2188

Alternate gene names: 51596514

Gene position: 2578173-2576875 (Counterclockwise)

Preceding gene: 161760573

Following gene: 51596513

Centisome position: 54.34

GC content: 46.73

Gene sequence:

>1299_bases
GTGACTACTTCATTACACACTACAAACACTGTGGCGCCAGCATCAACAAAAAATGATGATGACACTGTTTTCACTACGAT
CCCTAAACTGCCTCCCCTAAATAAGCGTCCTTATATACAACAAGGTACGCCAGAATTCATCCGCGTTGCTCTGGCTTTAT
TTTCGGCGGGGTTAGCAACTTTCGCCCTGCTTTACTGCGTACAACCTATTTTGCCCATGTTGTCGCAGGACTTTAGTACC
TCTCCTGCGTCCAGCAGTTTGTCACTTTCGATAGCCACCGGGATGCTGGCGTTGGGTTTGATGTTTACCGGCCCCCTTTC
TGATGCGATAGGCCGAAAATCAGTCATGGTCGTGGCGTTGCTATTGGCCGCGGTTTGCACAATAGTTTGCTCTTTTATGA
CCAGTTGGCATGGGATTTTGCTAATGCGCGCATTGACCGGTCTATCCTTAAGCGGAGTTGCCGCGGTGGCAATGACCTAT
TTGAGTGAAGAGATCCATCCTAATTTTATTGCGCTATCAATGGGGTTGTATATCAGCGGTAGTTCTATTGGTGGCATGAG
TGGGCGTTTGGTGGCTGGGGTATTAAGCGATCTCTTTTCCTGGCGCGTATCACTGCTAGTACTCGGATTATTTGCTTTAG
CTGCTGCTTGCTTGTTTTGGTTTATCCTCCCAGCGTCTAAACACTTTCGTGCAAGTTCATTGCGCCCCAGAACGTTGTTA
ATCAATTTTAAACTGCACTGGCGTGACTCCGGCTTACCCCTACTATTTGCTGAAGGTTTTCTCATTATGGGGGGGTTCGT
CACCTTATTTAATTATATCGGCTATCGGTTACTGGATGGGCCTTATTATCTCAGCCCGACCATCGTAGGGCTATTATCCA
TTGTTTATTTAACGGGTTCTTATAGTTCACCTAAAGCGGGTTCACTCAGTAATCGCTACGGGCGAGGCCTAATTTTATTG
GCCTCTATCGGTATGATGTTGGTTGGTGTTGTGATCACCAGTTTTCCGTCAGTGATCATGATTTTTATTGGTATGATGTT
CGTTGCAGCAGGATTCTTTGCCGCTCACTCCGTTGTCAGTAGCTGGGTTGGTTGCAGAGCACGTCGTGCTAAGGCACAAG
CTTCGTCACTTTATCTGTTTTGTTACTATGCCGGTTCCAGCGTAGCCGGTACGTTAGGTGGCGTTTTTTGGTTACATTTA
GGCTGGACAGGTGTTGTTGTTTTTATTACCGCCCTTTTAGTTATCGCGTTGTTTATCGCTCAGCGATTACGAAAGTTGGT
AGGAACAGCCAAGCGTTGA

Upstream 100 bases:

>100_bases
TGTACTAATTTAACCGTGTACTAATTTAACCGTGTACTAATTTAACTGTATATTAATTTAACTGTGTACTAATTTGGCTA
TGTATTAATAAGGCTATACC

Downstream 100 bases:

>100_bases
GACTCCACTCTCTATGTGTCTTGCTACCGAAAAATGAGCTCGGTAAACATATGAGGGTGAGTCGCGAATTCTCACGTTTT
AAGCGCCCTTTTCTGTTTTA

Product: MFS multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTTSLHTTNTVAPASTKNDDDTVFTTIPKLPPLNKRPYIQQGTPEFIRVALALFSAGLATFALLYCVQPILPMLSQDFST
SPASSSLSLSIATGMLALGLMFTGPLSDAIGRKSVMVVALLLAAVCTIVCSFMTSWHGILLMRALTGLSLSGVAAVAMTY
LSEEIHPNFIALSMGLYISGSSIGGMSGRLVAGVLSDLFSWRVSLLVLGLFALAAACLFWFILPASKHFRASSLRPRTLL
INFKLHWRDSGLPLLFAEGFLIMGGFVTLFNYIGYRLLDGPYYLSPTIVGLLSIVYLTGSYSSPKAGSLSNRYGRGLILL
ASIGMMLVGVVITSFPSVIMIFIGMMFVAAGFFAAHSVVSSWVGCRARRAKAQASSLYLFCYYAGSSVAGTLGGVFWLHL
GWTGVVVFITALLVIALFIAQRLRKLVGTAKR

Sequences:

>Translated_432_residues
MTTSLHTTNTVAPASTKNDDDTVFTTIPKLPPLNKRPYIQQGTPEFIRVALALFSAGLATFALLYCVQPILPMLSQDFST
SPASSSLSLSIATGMLALGLMFTGPLSDAIGRKSVMVVALLLAAVCTIVCSFMTSWHGILLMRALTGLSLSGVAAVAMTY
LSEEIHPNFIALSMGLYISGSSIGGMSGRLVAGVLSDLFSWRVSLLVLGLFALAAACLFWFILPASKHFRASSLRPRTLL
INFKLHWRDSGLPLLFAEGFLIMGGFVTLFNYIGYRLLDGPYYLSPTIVGLLSIVYLTGSYSSPKAGSLSNRYGRGLILL
ASIGMMLVGVVITSFPSVIMIFIGMMFVAAGFFAAHSVVSSWVGCRARRAKAQASSLYLFCYYAGSSVAGTLGGVFWLHL
GWTGVVVFITALLVIALFIAQRLRKLVGTAKR
>Mature_431_residues
TTSLHTTNTVAPASTKNDDDTVFTTIPKLPPLNKRPYIQQGTPEFIRVALALFSAGLATFALLYCVQPILPMLSQDFSTS
PASSSLSLSIATGMLALGLMFTGPLSDAIGRKSVMVVALLLAAVCTIVCSFMTSWHGILLMRALTGLSLSGVAAVAMTYL
SEEIHPNFIALSMGLYISGSSIGGMSGRLVAGVLSDLFSWRVSLLVLGLFALAAACLFWFILPASKHFRASSLRPRTLLI
NFKLHWRDSGLPLLFAEGFLIMGGFVTLFNYIGYRLLDGPYYLSPTIVGLLSIVYLTGSYSSPKAGSLSNRYGRGLILLA
SIGMMLVGVVITSFPSVIMIFIGMMFVAAGFFAAHSVVSSWVGCRARRAKAQASSLYLFCYYAGSSVAGTLGGVFWLHLG
WTGVVVFITALLVIALFIAQRLRKLVGTAKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787880, Length=419, Percent_Identity=66.3484486873508, Blast_Score=560, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46273; Mature: 46141

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSLHTTNTVAPASTKNDDDTVFTTIPKLPPLNKRPYIQQGTPEFIRVALALFSAGLAT
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FALLYCVQPILPMLSQDFSTSPASSSLSLSIATGMLALGLMFTGPLSDAIGRKSVMVVAL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHH
LLAAVCTIVCSFMTSWHGILLMRALTGLSLSGVAAVAMTYLSEEIHPNFIALSMGLYISG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECEEEEC
SSIGGMSGRLVAGVLSDLFSWRVSLLVLGLFALAAACLFWFILPASKHFRASSLRPRTLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
INFKLHWRDSGLPLLFAEGFLIMGGFVTLFNYIGYRLLDGPYYLSPTIVGLLSIVYLTGS
EEEEEEEECCCCCEEHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
YSSPKAGSLSNRYGRGLILLASIGMMLVGVVITSFPSVIMIFIGMMFVAAGFFAAHSVVS
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWVGCRARRAKAQASSLYLFCYYAGSSVAGTLGGVFWLHLGWTGVVVFITALLVIALFIA
HHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLRKLVGTAKR
HHHHHHHCCCCC
>Mature Secondary Structure 
TTSLHTTNTVAPASTKNDDDTVFTTIPKLPPLNKRPYIQQGTPEFIRVALALFSAGLAT
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FALLYCVQPILPMLSQDFSTSPASSSLSLSIATGMLALGLMFTGPLSDAIGRKSVMVVAL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHH
LLAAVCTIVCSFMTSWHGILLMRALTGLSLSGVAAVAMTYLSEEIHPNFIALSMGLYISG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECEEEEC
SSIGGMSGRLVAGVLSDLFSWRVSLLVLGLFALAAACLFWFILPASKHFRASSLRPRTLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
INFKLHWRDSGLPLLFAEGFLIMGGFVTLFNYIGYRLLDGPYYLSPTIVGLLSIVYLTGS
EEEEEEEECCCCCEEHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
YSSPKAGSLSNRYGRGLILLASIGMMLVGVVITSFPSVIMIFIGMMFVAAGFFAAHSVVS
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWVGCRARRAKAQASSLYLFCYYAGSSVAGTLGGVFWLHLGWTGVVVFITALLVIALFIA
HHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLRKLVGTAKR
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]