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The map label for this gene is trpD

Identifier: 51596454

GI number: 51596454

Start: 2505234

End: 2506232

Strand: Reverse

Name: trpD

Synonym: YPTB2128

Alternate gene names: 51596454

Gene position: 2506232-2505234 (Counterclockwise)

Preceding gene: 51596455

Following gene: 51596453

Centisome position: 52.82

GC content: 53.25

Gene sequence:

>999_bases
ATGCAACATTTATTCGAAAAACTGTTCCGGGCTGAGTCAATGAGCCAAGAAGAAAGCCAGCAACTGTTTGCGGCGATTGT
ACGTGGTGAACTCGAGCCAAGCCAACTGGCCGCAGTGCTAATCAGCATGAAAGTACGCGGGGAGACCCCAGCGGAGATTG
CCGGGGCAGCTCAAGCTTTACTGGCAGATGCGCAACACTTTCCACGCCCAGACTACCTGTTTGCCGATATTGTCGGGACC
GGCGGTGATGGCACCAACAGTATTAATATCTCCACCGCCAGTGCCTTTGTCGCGGCTAGCTGTGGCGTAAAAGTGGCTAA
ACATGGTAACCGCAGTGTTTCTAGCCGTTCCGGTTCATCCGATCTGCTGGCGGCATTTGGTATCCGTTTGGACATGAGTG
CCGAGCAATCACGGTTGGCGTTGGACGATCTCGGGGTCTGCTTCCTGTTTGCGCCGCAATATCACACGGGTTTTCGTCAT
GCGATGCCAGTACGCCAGCAGTTAAAGACCCGCACCCTGTTTAATGTGTTGGGGCCGTTGATCAACCCCGCCCGCCCGCC
GCTGGCGCTCATTGGCGTCTATAGCCCTGAGTTAGTGTTACCGATCGCTCAAACGCTGAAAGTACTGGGTTATCAACGTG
CGGCAGTGGTACATGGCGGTGGAATGGATGAAGTGGCTATTCATGCCCCGACGCAGGTGGCTGAACTGAATAATGGCAGT
ATTGAAAGCTATCAATTGACGCCAGAAGATTTTGGTTTGAATCGCTACCCGCTTGCCGCTCTACAAGGCGGTATGCCGGA
AGAAAACCGTGACATTTTAGCACGGTTGTTACAAGGTAAAGGTGAAACAGCACATGCGGCCGCCGTTGCTGCAAACGTCG
CCTTGCTGCTGAAGTTATACGGCCAAGAAAACCTGCGCCATAATGCGCAACAGGCATTGGAAATGATTCACAGCGGTCAG
GCTTTTGATCGTGTTACTGCTCTGGCAGCGAGAGGATAA

Upstream 100 bases:

>100_bases
GTGGCTACCAATTCCACCCGGAATCGATTTTAACCACCCACGGTGCGCGTTTACTTGAACAAACACTGGCCTGGGCGTTA
GCGTAATTAAGGAGTTTATG

Downstream 100 bases:

>100_bases
ATCATGCAGGAAACTGGGGGTTACAAAACCGAGGGTTATAACGTTGGCAGTGACAAAGTTGACAGTGATAAAACCAAAAC
CGTGCTCCACCAAATCGTAC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQHLFEKLFRAESMSQEESQQLFAAIVRGELEPSQLAAVLISMKVRGETPAEIAGAAQALLADAQHFPRPDYLFADIVGT
GGDGTNSINISTASAFVAASCGVKVAKHGNRSVSSRSGSSDLLAAFGIRLDMSAEQSRLALDDLGVCFLFAPQYHTGFRH
AMPVRQQLKTRTLFNVLGPLINPARPPLALIGVYSPELVLPIAQTLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNNGS
IESYQLTPEDFGLNRYPLAALQGGMPEENRDILARLLQGKGETAHAAAVAANVALLLKLYGQENLRHNAQQALEMIHSGQ
AFDRVTALAARG

Sequences:

>Translated_332_residues
MQHLFEKLFRAESMSQEESQQLFAAIVRGELEPSQLAAVLISMKVRGETPAEIAGAAQALLADAQHFPRPDYLFADIVGT
GGDGTNSINISTASAFVAASCGVKVAKHGNRSVSSRSGSSDLLAAFGIRLDMSAEQSRLALDDLGVCFLFAPQYHTGFRH
AMPVRQQLKTRTLFNVLGPLINPARPPLALIGVYSPELVLPIAQTLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNNGS
IESYQLTPEDFGLNRYPLAALQGGMPEENRDILARLLQGKGETAHAAAVAANVALLLKLYGQENLRHNAQQALEMIHSGQ
AFDRVTALAARG
>Mature_332_residues
MQHLFEKLFRAESMSQEESQQLFAAIVRGELEPSQLAAVLISMKVRGETPAEIAGAAQALLADAQHFPRPDYLFADIVGT
GGDGTNSINISTASAFVAASCGVKVAKHGNRSVSSRSGSSDLLAAFGIRLDMSAEQSRLALDDLGVCFLFAPQYHTGFRH
AMPVRQQLKTRTLFNVLGPLINPARPPLALIGVYSPELVLPIAQTLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNNGS
IESYQLTPEDFGLNRYPLAALQGGMPEENRDILARLLQGKGETAHAAAVAANVALLLKLYGQENLRHNAQQALEMIHSGQ
AFDRVTALAARG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=332, Percent_Identity=77.4096385542169, Blast_Score=491, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6320561, Length=328, Percent_Identity=33.2317073170732, Blast_Score=129, Evalue=7e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_YERP3 (A7FI31)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400909.1
- ProteinModelPortal:   A7FI31
- SMR:   A7FI31
- STRING:   A7FI31
- GeneID:   5387267
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1934
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   YPSE349747:YPSIP31758_1934-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35499; Mature: 35499

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLFEKLFRAESMSQEESQQLFAAIVRGELEPSQLAAVLISMKVRGETPAEIAGAAQAL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LADAQHFPRPDYLFADIVGTGGDGTNSINISTASAFVAASCGVKVAKHGNRSVSSRSGSS
HHHHHHCCCCCEEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
DLLAAFGIRLDMSAEQSRLALDDLGVCFLFAPQYHTGFRHAMPVRQQLKTRTLFNVLGPL
HHHHHHCEEEECCCCHHHHHHHHCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
INPARPPLALIGVYSPELVLPIAQTLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNNGS
CCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCHHEECCCCC
IESYQLTPEDFGLNRYPLAALQGGMPEENRDILARLLQGKGETAHAAAVAANVALLLKLY
CEEEEECHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GQENLRHNAQQALEMIHSGQAFDRVTALAARG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MQHLFEKLFRAESMSQEESQQLFAAIVRGELEPSQLAAVLISMKVRGETPAEIAGAAQAL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LADAQHFPRPDYLFADIVGTGGDGTNSINISTASAFVAASCGVKVAKHGNRSVSSRSGSS
HHHHHHCCCCCEEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
DLLAAFGIRLDMSAEQSRLALDDLGVCFLFAPQYHTGFRHAMPVRQQLKTRTLFNVLGPL
HHHHHHCEEEECCCCHHHHHHHHCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
INPARPPLALIGVYSPELVLPIAQTLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNNGS
CCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCHHEECCCCC
IESYQLTPEDFGLNRYPLAALQGGMPEENRDILARLLQGKGETAHAAAVAANVALLLKLY
CEEEEECHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GQENLRHNAQQALEMIHSGQAFDRVTALAARG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA