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The map label for this gene is dsbB

Identifier: 51596396

GI number: 51596396

Start: 2437078

End: 2437608

Strand: Reverse

Name: dsbB

Synonym: YPTB2070

Alternate gene names: 51596396

Gene position: 2437608-2437078 (Counterclockwise)

Preceding gene: 51596397

Following gene: 51596394

Centisome position: 51.38

GC content: 46.33

Gene sequence:

>531_bases
ATGTTGCAATTCCTTAACCGCTGTTCCCGAGGACGCGGTGCTTGGCTATTAATGGCCCTGACTGCATTTCTATTAGAGTT
AACTGCGCTCTATTTTCAACACATTATGTTGCTACAACCGTGTGTAATGTGTATTTATGAGCGTGTCGCATTATTCGGTA
TTCTCGGTGCATCACTATTGGGTGCAATAGCCCCGAGATCACCACTACGCTATTTAGCTATTGCAGTTTGGATCTACAGC
GCGTGGAAAGGGGTTCAGCTAGCTTGGGCACACACTATGCTGCAGTTGAATCCATCCCCATTTAACACCTGCGATTTCTT
CGTCAACTTCCCTTCATGGCTACCCTTGGATAAATGGTTACCCGCCGTGTTCGCCGCCAGTGGCGATTGCTCGGAAAGAC
AATGGCAGTTTATGTCATTAGAAATGCCACAATGGTTAGTCGGTATTTTTGCTGCATATCTGGTTATCGCCGTACTCGTT
CTGATCAGCCAATTTGTTAAACCTAAAAGACGCGATCTGTTCGGCCGATAA

Upstream 100 bases:

>100_bases
AAAACTGATTTTTACCTAATTTTGCTTTTGGGTAGCTGGCAGAAAAGATGAATTGGTTTACACTGCCGGTACAATTGCTT
ACTGCATGGAAAATAAAGAT

Downstream 100 bases:

>100_bases
TTTTTATACATATCTTTATTATCAATGGCGCCTCTCTGGCGCCATTTTTATATCAGATTCAAACGGTCTGTTAATCCTAA
TGAACACTTAATTCCATGCA

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLLGAIAPRSPLRYLAIAVWIYS
AWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLVIAVLV
LISQFVKPKRRDLFGR

Sequences:

>Translated_176_residues
MLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLLGAIAPRSPLRYLAIAVWIYS
AWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLVIAVLV
LISQFVKPKRRDLFGR
>Mature_176_residues
MLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLLGAIAPRSPLRYLAIAVWIYS
AWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLVIAVLV
LISQFVKPKRRDLFGR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=176, Percent_Identity=73.2954545454545, Blast_Score=281, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_YERPA (Q1C7V4)

Other databases:

- EMBL:   CP000308
- RefSeq:   YP_651413.1
- ProteinModelPortal:   Q1C7V4
- SMR:   Q1C7V4
- STRING:   Q1C7V4
- GeneID:   4119519
- GenomeReviews:   CP000308_GR
- KEGG:   ypa:YPA_1501
- eggNOG:   COG1495
- HOGENOM:   HBG637909
- ProtClustDB:   PRK01749
- BioCyc:   YPES360102:YPA_1501-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 20107; Mature: 20107

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b2e7658)-; HASH(0x1baabf08)-; HASH(0x19494440)-; HASH(0x1b292de4)-;

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLL
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPRSPLRYLAIAVWIYSAWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWL
HHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCHHHHH
PAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLVIAVLVLISQFVKPKRRDLFGR
HHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCH
>Mature Secondary Structure
MLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLL
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPRSPLRYLAIAVWIYSAWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWL
HHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCHHHHH
PAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLVIAVLVLISQFVKPKRRDLFGR
HHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA