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The map label for this gene is mlc [C]

Identifier: 51596344

GI number: 51596344

Start: 2375106

End: 2376260

Strand: Direct

Name: mlc [C]

Synonym: YPTB2018

Alternate gene names: 51596344

Gene position: 2375106-2376260 (Clockwise)

Preceding gene: 51596343

Following gene: 51596345

Centisome position: 50.06

GC content: 55.06

Gene sequence:

>1155_bases
TTGAAGAAGCGGGTCTGCGCTGGGATTAATATTAAGGACACCATGAATATCCGACCTGAACGGCTTGAACTGCGCGGATC
ACAGCGCTTACTGCTGGAACTGATCCGCCGTCATGCGCCCGTCACACGTGCGGAGTTAGCGCGCTTGTCGAACCTGACCG
CGGGCGCGATCACCCAACAGTGCCGGGAATTAATCTTTGCCGGTTTGGTGGTGGAAGGGGAACGCAATACCGGGCAGCGT
GGTCAGCCATCGCTGCCGTTGCGTCTCAACCCTGGTGGTGGTTGCGCTATTGGTTTGTCGTTCAGCCCCGGTTTTATCGA
TATGACCGTGGTCGATCTCAGTGGCCGCCAGTTATTATCGGTTGCCGAGCCTCATCAGGAAAATCAGCCGCTGACTGCGA
CGCTTTGCCAAATCAAAACGCTGGTCGAACAGACGCTGAAGAAACGCCAGCTACAGCACGCACGTATTATCGGCATTGGC
TATGCGGTACCAGGTTTTCTTAAGGCTGATGGGCACAAACGCCATTGTGTGCCGTGGCTGCATACTTGGCGAGAAGCGGA
CCTCCAGCAGGTGTTTGCCGATAATCTGCCGTGGCCTACCCGGGTGGAGAACAATGCCAATGCTTCAGCTATCGGCGAAC
TGTACAGCGGCGAGTGGAACAACTACAGCGATCTGACTTTTATCGACCTTGGCTATGGCATCGGCGCGGGTGTGATCTCT
GGGCATAAGTTGTTGCGCGGTGGTTTTTTCAATGCTGGGGAAGTCGGCATGGCGTTCCCTTCAGGTACACCGCGTCCGTC
ATATAAAGATTTACTGGCTACGCTGGAGCGTGAGGGATTTAGCGAAACGCAACTGCCAGTGCTGAGCGCTGGGCGGCATC
CGGTGTTGGAAAAGTGGTTTGAACGCTGCTGTGATCAAGTGCAACAAACGGTGTTTGGTTGTGTGCAATGGGTTGACCCA
CAACTGATTGTACTGGGGGGGGCTATGCCGAAGCCCATCATCAGCCGCCTTGTGCAGGAAATAAGCCAACGCCTGAATAC
CTGCCTGGATCCTGAGCGTCCAAAAGTAACCTTAGCCGCTTCGTCAATGGGGGCGGAAAGCGCTTCACGTGGCGCGGCGA
TGATCCCTCTGTATCAGGTGATTAATGAGGATTAA

Upstream 100 bases:

>100_bases
AAATTCGGGTATGATAGTCGCCCGGAGATCCTAAGCTGGCTGCGTGAAGGGCTGATCGACATGCTTAGCCACGATGATAT
TCCATATCTTCAGGCGCTAA

Downstream 100 bases:

>100_bases
GGGGGAGATATACGGCCCTAAAAATTCTGTGAAGCTGAAGGATTGGACACAATACGATTAGAGCCTGTAAGTGACTGATG
CAAGCAACCTACTGGTATAA

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKKRVCAGINIKDTMNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQCRELIFAGLVVEGERNTGQR
GQPSLPLRLNPGGGCAIGLSFSPGFIDMTVVDLSGRQLLSVAEPHQENQPLTATLCQIKTLVEQTLKKRQLQHARIIGIG
YAVPGFLKADGHKRHCVPWLHTWREADLQQVFADNLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVIS
GHKLLRGGFFNAGEVGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWFERCCDQVQQTVFGCVQWVDP
QLIVLGGAMPKPIISRLVQEISQRLNTCLDPERPKVTLAASSMGAESASRGAAMIPLYQVINED

Sequences:

>Translated_384_residues
MKKRVCAGINIKDTMNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQCRELIFAGLVVEGERNTGQR
GQPSLPLRLNPGGGCAIGLSFSPGFIDMTVVDLSGRQLLSVAEPHQENQPLTATLCQIKTLVEQTLKKRQLQHARIIGIG
YAVPGFLKADGHKRHCVPWLHTWREADLQQVFADNLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVIS
GHKLLRGGFFNAGEVGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWFERCCDQVQQTVFGCVQWVDP
QLIVLGGAMPKPIISRLVQEISQRLNTCLDPERPKVTLAASSMGAESASRGAAMIPLYQVINED
>Mature_384_residues
MKKRVCAGINIKDTMNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQCRELIFAGLVVEGERNTGQR
GQPSLPLRLNPGGGCAIGLSFSPGFIDMTVVDLSGRQLLSVAEPHQENQPLTATLCQIKTLVEQTLKKRQLQHARIIGIG
YAVPGFLKADGHKRHCVPWLHTWREADLQQVFADNLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVIS
GHKLLRGGFFNAGEVGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWFERCCDQVQQTVFGCVQWVDP
QLIVLGGAMPKPIISRLVQEISQRLNTCLDPERPKVTLAASSMGAESASRGAAMIPLYQVINED

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1787878, Length=228, Percent_Identity=27.1929824561404, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786891, Length=230, Percent_Identity=25.2173913043478, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42248; Mature: 42248

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRVCAGINIKDTMNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQ
CCCCEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHH
CRELIFAGLVVEGERNTGQRGQPSLPLRLNPGGGCAIGLSFSPGFIDMTVVDLSGRQLLS
HHHHHHHHEEEECCCCCCCCCCCCCCEEECCCCCEEEEECCCCCEEEEEEEECCCCHHHH
VAEPHQENQPLTATLCQIKTLVEQTLKKRQLQHARIIGIGYAVPGFLKADGHKRHCVPWL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEECCCCCCCCCHHH
HTWREADLQQVFADNLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVIS
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
GHKLLRGGFFNAGEVGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWF
CHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHH
ERCCDQVQQTVFGCVQWVDPQLIVLGGAMPKPIISRLVQEISQRLNTCLDPERPKVTLAA
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SSMGAESASRGAAMIPLYQVINED
CCCCCCHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKKRVCAGINIKDTMNIRPERLELRGSQRLLLELIRRHAPVTRAELARLSNLTAGAITQQ
CCCCEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHH
CRELIFAGLVVEGERNTGQRGQPSLPLRLNPGGGCAIGLSFSPGFIDMTVVDLSGRQLLS
HHHHHHHHEEEECCCCCCCCCCCCCCEEECCCCCEEEEECCCCCEEEEEEEECCCCHHHH
VAEPHQENQPLTATLCQIKTLVEQTLKKRQLQHARIIGIGYAVPGFLKADGHKRHCVPWL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEECCCCCCCCCHHH
HTWREADLQQVFADNLPWPTRVENNANASAIGELYSGEWNNYSDLTFIDLGYGIGAGVIS
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
GHKLLRGGFFNAGEVGMAFPSGTPRPSYKDLLATLEREGFSETQLPVLSAGRHPVLEKWF
CHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHH
ERCCDQVQQTVFGCVQWVDPQLIVLGGAMPKPIISRLVQEISQRLNTCLDPERPKVTLAA
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SSMGAESASRGAAMIPLYQVINED
CCCCCCHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]