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The map label for this gene is hutI

Identifier: 51596292

GI number: 51596292

Start: 2316318

End: 2317538

Strand: Reverse

Name: hutI

Synonym: YPTB1966

Alternate gene names: 51596292

Gene position: 2317538-2316318 (Counterclockwise)

Preceding gene: 51596293

Following gene: 51596291

Centisome position: 48.85

GC content: 50.61

Gene sequence:

>1221_bases
ATGGTATCAGTAACTCACTGTGACAGCTTATGGTTCGGGGCCGATATCATTACGATGCGCGGGGGAAATTATCAGTTGAT
TCCGCAAGGGGCAATCGCTGTCACTGGCGATAAGATAGTCTGGATTGGGCCACATGCCGAATTACCGCCTATTCATGCCG
CACGTCAGGTCGTATATGAAGGTGGTCTTATCACCCCCGGATTGATTGACTGTCACACCCATCTCGTGTTTGGCGGTGAT
CGTAGCAATGAATTTGAGCAACGCCTTAACGGGGTCAGCTATGCCGAAATTGCTGCTAATGGCGGTGGTATTATTTCAAC
CGTCAGAGCCACACGCCAAGCTAGCGAACAGCAACTACTGGAACAAGCCCTATTTCGTCTGAAGCCCTTACTTGCTGAAG
GGGTGACTACGATTGAGATTAAGTCTGGCTATGGCCTTAATCTTGAAAGTGAAATAAAAATGTTGCGAGTGGCCCGCCGA
TTGGGGGAGTTACTGCCTATTGACGTCAAAACGACTTGTTTGGCCGCCCATGCGCTACCGCCCGAGTTTATCGGGCAGCC
TGATGATTATATTGATGTCGTATGTAATAGCATTATTCCTCAGGTGGCAGTTGAAAACTTAGCCGATGCCGTGGACGCAT
TTTGCGAACATTTAGCTTTTTCACCGGCTCAAGTTGAGCGAGTATTTTTAGCCGCACAAAAAGCCGGGCTACCTGTAAAA
CTGCACGCAGAGCAACTTTCTGCTCTCCGTGGCGCGACTCTGGCCGCTAAATTCCATGCGATATCGGCAGACCATCTGGA
GTACGCGACTGAATCTGATGTCCAGGCTATGGCAAAGGCGGGTACTGTCGCAGTCTTACTACCAGGTGCCTACTACTTAT
TGCGGGAAACACAATGCCCCCCAATTGATCTGTTCCGCCAGTATAAGGTCCCCATGGCACTGGCCAGTGATGCCAACCCA
GGGACATCTCCGGTACTTTCACTACGCTTGATGCTCAATATGGCTTGCACGTTATTCCGCATGACACCAGAAGAAGCACT
GGCTGGTGTCACGTGCCACGCAGCTCAAGCTCTTGGTGTACAACAGACTCAAGGTACGTTGGAGACAGGGAAATTGGCTA
ACTGGGTGCATTGGCCCTTATCACACCCAGCCGAGTTAGCTTATTGGTTAGGAGGGCAATTACCTGCCACTGTCGTATTC
CGAGGAGAAGTACGCCCATGA

Upstream 100 bases:

>100_bases
CAAGTTGATTTCGTTCATCCAGTAAATGATTCGGGTGACAAATCTGCCGAGTGCAGCTAACACCGCAGCAACGTCAAATG
AGAAGGGAAAGGGGAAAGAA

Downstream 100 bases:

>100_bases
ATTTAACTGACTCTTACTACTTTCAGGGCGGAAAAATACCTTTGCTCATTAGCATTCCACATGCAGGTACACGCCTGACT
CCCGCAGTTGAAGCTGGCCT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYEGGLITPGLIDCHTHLVFGGD
RSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLLEQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARR
LGELLPIDVKTTCLAAHALPPEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMAKAGTVAVLLPGAYYLLRETQCPPIDLFRQYKVPMALASDANP
GTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGVQQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVF
RGEVRP

Sequences:

>Translated_406_residues
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYEGGLITPGLIDCHTHLVFGGD
RSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLLEQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARR
LGELLPIDVKTTCLAAHALPPEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMAKAGTVAVLLPGAYYLLRETQCPPIDLFRQYKVPMALASDANP
GTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGVQQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVF
RGEVRP
>Mature_406_residues
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYEGGLITPGLIDCHTHLVFGGD
RSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLLEQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARR
LGELLPIDVKTTCLAAHALPPEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMAKAGTVAVLLPGAYYLLRETQCPPIDLFRQYKVPMALASDANP
GTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGVQQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVF
RGEVRP

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=351, Percent_Identity=36.4672364672365, Blast_Score=192, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17555004, Length=339, Percent_Identity=35.3982300884956, Blast_Score=201, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_YERP3 (A7FIK8)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401086.1
- ProteinModelPortal:   A7FIK8
- SMR:   A7FIK8
- STRING:   A7FIK8
- GeneID:   5386126
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2113
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   YPSE349747:YPSIP31758_2113-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 43778; Mature: 43778

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: BINDING 81-81 BINDING 94-94 BINDING 144-144 BINDING 177-177 BINDING 245-245

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYE
CCEEEECCCCEECCEEEEEECCCEEEEECCEEEEECCEEEEECCCCCCCCHHHHHHHHHC
GGLITPGLIDCHTHLVFGGDRSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLL
CCCCCCCCEECEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
EQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARRLGELLPIDVKTTCLAAHALP
HHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
PEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEE
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMAKAGTVAVLLPGAYYLLRETQCP
EEHHHHHHHHCCHHHHHHEECCHHHHHHCCHHHHHHHHHCCCEEEEECCCEEEEECCCCC
PIDLFRQYKVPMALASDANPGTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGV
CHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHCCC
QQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVFRGEVRP
HHCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEEEECCCCC
>Mature Secondary Structure
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYE
CCEEEECCCCEECCEEEEEECCCEEEEECCEEEEECCEEEEECCCCCCCCHHHHHHHHHC
GGLITPGLIDCHTHLVFGGDRSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLL
CCCCCCCCEECEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
EQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARRLGELLPIDVKTTCLAAHALP
HHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
PEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEE
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMAKAGTVAVLLPGAYYLLRETQCP
EEHHHHHHHHCCHHHHHHEECCHHHHHHCCHHHHHHHHHCCCEEEEECCCEEEEECCCCC
PIDLFRQYKVPMALASDANPGTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGV
CHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHCCC
QQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVFRGEVRP
HHCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA