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The map label for this gene is astE

Identifier: 51596289

GI number: 51596289

Start: 2312116

End: 2313111

Strand: Direct

Name: astE

Synonym: YPTB1963

Alternate gene names: 51596289

Gene position: 2312116-2313111 (Clockwise)

Preceding gene: 51596288

Following gene: 51596290

Centisome position: 48.73

GC content: 48.09

Gene sequence:

>996_bases
ATGATGCTGGATTTTTTAGCGATAACCCTATCGGGTAAACCTCCACAAGTCATACAGGGTGAAACCGTTAATCTGAAATG
GCAATGGCTCGGTGAGGGGATATTGACACTGGTTCCGCACCGCAGCTACACACAATCGGTGGTGATCTCTGCCGGTATCC
ACGGCAATGAAACGGCACCCATTGAAATTTTGAATCAATTAGTCACCGATTTATTAGCGGGTCAACTGCCGCTGTCCGTC
CGTCTGTTAGTGTTATTGGGAAATCCACCGGCGATCCGCAAAGGGAAGCGGTACCTCAGCAATGACATTAACCGTATGTT
TGGTGGGCGTTATCAGCACTATACACCCAGTGACGAGACGCGAAGGGCGAGTACTCTGGAGCAACGGGTGATGGCATTTT
TCCAGGCAAGTCACACATCAGAGCGTTTGCATTATGATCTACACACCGCAATTCGGGGGTCCTATCATCCTCGCTTTGGT
TTGTTACCCTACCAGCAGACCCCTTATTCCGCTGCTATGTTTCGTTGGTTGCGGGACATCGAACTGGATGCTTTGGTTAT
GCACACCTCCGCAGGAGGGACATTCGCTCACTTTAGCAGTGAGCGCTGTCAGGCAGCCAGTTGTACGTTGGAGTTAGGCA
AAGCATTACCTTTTGGTGAGAATCAATTATCACAATTCAGTGCGATCACCCAAGGATTACGCTCCTTAGTCAGTGATAGT
GCCTTGCCTGCACGTAAGACAGAGAACATGAAGTACTACCGGGTCGTTAAATCACTGCTTAGGCAACACCCTGATTTTAA
ACTACGGGTGGCCGAGGATACGGTAAATTTCACACGCTTCGCACAAGGCACTCTACTTACAGAACAACCCAATGATAACT
ATCGTGTTGAACACCCCTATGAGTGGATCTTATTTCCAAATCCACATGTTGCGTTGGGATTACGGGCTGGGATGATGTTG
GTAAAAATGTGTGAAAGTGAATTACCGATTACATGA

Upstream 100 bases:

>100_bases
AATCCTCAATCTGGGGCCGGTGTACCCGTTCCAGCGCAATTAGCCGGTGTGGCTTTAGCGAATAACCGAACGGCTCAATG
ATAGAACCAATAGAGGAGCG

Downstream 100 bases:

>100_bases
GCTTGTTGGGGGCCAATACCGATGTGGGCGGTTCTCTGGAGTTATACCCATACAAATAGTAATAATTAATCTAATTTCAA
ATGAACTGTCTTGACGGTTC

Product: succinylglutamate desuccinylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MMLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAPIEILNQLVTDLLAGQLPLSV
RLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDETRRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFG
LLPYQQTPYSAAMFRWLRDIELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDS
ALPARKTENMKYYRVVKSLLRQHPDFKLRVAEDTVNFTRFAQGTLLTEQPNDNYRVEHPYEWILFPNPHVALGLRAGMML
VKMCESELPIT

Sequences:

>Translated_331_residues
MMLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAPIEILNQLVTDLLAGQLPLSV
RLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDETRRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFG
LLPYQQTPYSAAMFRWLRDIELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDS
ALPARKTENMKYYRVVKSLLRQHPDFKLRVAEDTVNFTRFAQGTLLTEQPNDNYRVEHPYEWILFPNPHVALGLRAGMML
VKMCESELPIT
>Mature_331_residues
MMLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAPIEILNQLVTDLLAGQLPLSV
RLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDETRRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFG
LLPYQQTPYSAAMFRWLRDIELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDS
ALPARKTENMKYYRVVKSLLRQHPDFKLRVAEDTVNFTRFAQGTLLTEQPNDNYRVEHPYEWILFPNPHVALGLRAGMML
VKMCESELPIT

Specific function: Transforms N(2)-succinylglutamate into succinate and glutamate [H]

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788040, Length=322, Percent_Identity=49.0683229813665, Blast_Score=325, Evalue=3e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007036
- InterPro:   IPR016681 [H]

Pfam domain/function: PF04952 AstE_AspA [H]

EC number: =3.5.1.96 [H]

Molecular weight: Translated: 37400; Mature: 37400

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAP
CCEEEEEEEECCCCCCEECCCEEEEEEEEECCCEEEECCCCCCCCEEEEEECCCCCCCCH
IEILNQLVTDLLAGQLPLSVRLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDET
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
RRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFGLLPYQQTPYSAAMFRWLRDI
HHHHHHHHHHHHHHHHCCCHHHHEEHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
ELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDS
CCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
ALPARKTENMKYYRVVKSLLRQHPDFKLRVAEDTVNFTRFAQGTLLTEQPNDNYRVEHPY
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCEEEECCCCCCEEECCCE
EWILFPNPHVALGLRAGMMLVKMCESELPIT
EEEEECCCCEEEHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAP
CCEEEEEEEECCCCCCEECCCEEEEEEEEECCCEEEECCCCCCCCEEEEEECCCCCCCCH
IEILNQLVTDLLAGQLPLSVRLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDET
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
RRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFGLLPYQQTPYSAAMFRWLRDI
HHHHHHHHHHHHHHHHCCCHHHHEEHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
ELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDS
CCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
ALPARKTENMKYYRVVKSLLRQHPDFKLRVAEDTVNFTRFAQGTLLTEQPNDNYRVEHPY
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCEEEECCCCCCEEECCCE
EWILFPNPHVALGLRAGMMLVKMCESELPIT
EEEEECCCCEEEHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA