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The map label for this gene is tehB

Identifier: 51596273

GI number: 51596273

Start: 2288891

End: 2289778

Strand: Direct

Name: tehB

Synonym: YPTB1947

Alternate gene names: 51596273

Gene position: 2288891-2289778 (Clockwise)

Preceding gene: 51596272

Following gene: 51596274

Centisome position: 48.24

GC content: 45.16

Gene sequence:

>888_bases
ATGGAAAACACCTCTGCACAGCTAGCACCCACACTGCTATGTTACAAGAAACTCCCTGTCTGGAACCGTGATGGCGTACC
GGCAATGTTTCAGGAAAAGCACAATACGAAAGCGGGCACGTGGGCAAAACTGACCATTTTGGCTGGAGAGATGGATTTCT
TAATTCTTGATGAAGCCGGTAATACCGTGGAAAAGCACCAGTTCTCCTGCGAACAGCAACCACCATTTATCGAGCCACAA
GTCTGGCATCGCATTGCTACCTGCTCAGATGATCTGCAATGTCAGCTCAGTTTCTACTGCCAGCCAGAAGATTTTTACCA
TAAAAAATATAATTTAACCCCGACCCATTCTGAAGTCATTGAAGCGGTAAAAACAGTTAAGCCGGGGAAGGCGCTGGACT
TGGGGTGTGGCTCTGGACGCAACTCGCTGTACCTGAACCTATTGGGTTTCGATGTTACTGCTGTAGATAAAAATAACGAC
AGCATTGGTAATTTACAGCAGATCATTGATAAGGAAGCCCTGAAAGGGATTACTGCCAGCAGCTATAATATTAATGAGGC
CAGTCTGGATGAGCGCTACGATTTTATTCTATCAACCGTGGTCTTGATGTTCCTGCAACCAGAAAGAATCCCACATATTA
TCAGTAATATGCAGGAGTGTACTTTACCCGGCGGCTATAACCTGATTATCTCCGCAATGTCGACCGATGACTTCCCTTGC
ACCGTACCTTTCTCTTTCACATTCCAGTCGGGTGAGTTAAAAGATTATTATCAGGATTGGGCGATCCTCAAGTACAACGA
GGATGTCGGGCAACTTCACAAGACCGATGCACAAGGTAACCGGATAAAACTACGTTTTGCGACTTTATTGGCAAAAAAAA
TCTCATAA

Upstream 100 bases:

>100_bases
ATTTTCCCTTGTATGATTTAGCGACTTCATTTGATAACGTGGATGCGGTACTATATGTTGCATATAAAATGCATCTTTAA
GTTATCTAAGGAAAATCACG

Downstream 100 bases:

>100_bases
GTACATCACTCGGTGTAGACATCGCTGGCATCAGAATGGCTTTCAGGCGGCTGAAAATCAACATTTATGCAACTTAATGT
CAGGCATGTATCAATAATAG

Product: tellurite resistance protein TehB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MENTSAQLAPTLLCYKKLPVWNRDGVPAMFQEKHNTKAGTWAKLTILAGEMDFLILDEAGNTVEKHQFSCEQQPPFIEPQ
VWHRIATCSDDLQCQLSFYCQPEDFYHKKYNLTPTHSEVIEAVKTVKPGKALDLGCGSGRNSLYLNLLGFDVTAVDKNND
SIGNLQQIIDKEALKGITASSYNINEASLDERYDFILSTVVLMFLQPERIPHIISNMQECTLPGGYNLIISAMSTDDFPC
TVPFSFTFQSGELKDYYQDWAILKYNEDVGQLHKTDAQGNRIKLRFATLLAKKIS

Sequences:

>Translated_295_residues
MENTSAQLAPTLLCYKKLPVWNRDGVPAMFQEKHNTKAGTWAKLTILAGEMDFLILDEAGNTVEKHQFSCEQQPPFIEPQ
VWHRIATCSDDLQCQLSFYCQPEDFYHKKYNLTPTHSEVIEAVKTVKPGKALDLGCGSGRNSLYLNLLGFDVTAVDKNND
SIGNLQQIIDKEALKGITASSYNINEASLDERYDFILSTVVLMFLQPERIPHIISNMQECTLPGGYNLIISAMSTDDFPC
TVPFSFTFQSGELKDYYQDWAILKYNEDVGQLHKTDAQGNRIKLRFATLLAKKIS
>Mature_295_residues
MENTSAQLAPTLLCYKKLPVWNRDGVPAMFQEKHNTKAGTWAKLTILAGEMDFLILDEAGNTVEKHQFSCEQQPPFIEPQ
VWHRIATCSDDLQCQLSFYCQPEDFYHKKYNLTPTHSEVIEAVKTVKPGKALDLGCGSGRNSLYLNLLGFDVTAVDKNND
SIGNLQQIIDKEALKGITASSYNINEASLDERYDFILSTVVLMFLQPERIPHIISNMQECTLPGGYNLIISAMSTDDFPC
TVPFSFTFQSGELKDYYQDWAILKYNEDVGQLHKTDAQGNRIKLRFATLLAKKIS

Specific function: Probable S-adenosyl-L-methionine dependent methyltransferase that is responsible for tellurite resistance when present in high copy number. Binds tellurite and S-adenosyl- L-methionine [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm. Note=Probably a peripheral membrane protein that interacts with TehA (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TehB family [H]

Homologues:

Organism=Escherichia coli, GI1787700, Length=193, Percent_Identity=60.6217616580311, Blast_Score=251, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015392
- InterPro:   IPR014710
- InterPro:   IPR004537
- InterPro:   IPR014431
- InterPro:   IPR015985 [H]

Pfam domain/function: PF09313 DUF1971; PF03848 TehB [H]

EC number: NA

Molecular weight: Translated: 33291; Mature: 33291

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTSAQLAPTLLCYKKLPVWNRDGVPAMFQEKHNTKAGTWAKLTILAGEMDFLILDEAG
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCC
NTVEKHQFSCEQQPPFIEPQVWHRIATCSDDLQCQLSFYCQPEDFYHKKYNLTPTHSEVI
CCHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCHHHHHCCCCCCCCHHHHH
EAVKTVKPGKALDLGCGSGRNSLYLNLLGFDVTAVDKNNDSIGNLQQIIDKEALKGITAS
HHHHHCCCCCEEECCCCCCCCEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCC
SYNINEASLDERYDFILSTVVLMFLQPERIPHIISNMQECTLPGGYNLIISAMSTDDFPC
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCCCEEEEEEECCCCCCE
TVPFSFTFQSGELKDYYQDWAILKYNEDVGQLHKTDAQGNRIKLRFATLLAKKIS
EEEEEEEECCCCHHHHHCCCEEEEECCCHHHHHCCCCCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure
MENTSAQLAPTLLCYKKLPVWNRDGVPAMFQEKHNTKAGTWAKLTILAGEMDFLILDEAG
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCC
NTVEKHQFSCEQQPPFIEPQVWHRIATCSDDLQCQLSFYCQPEDFYHKKYNLTPTHSEVI
CCHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCHHHHHCCCCCCCCHHHHH
EAVKTVKPGKALDLGCGSGRNSLYLNLLGFDVTAVDKNNDSIGNLQQIIDKEALKGITAS
HHHHHCCCCCEEECCCCCCCCEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCC
SYNINEASLDERYDFILSTVVLMFLQPERIPHIISNMQECTLPGGYNLIISAMSTDDFPC
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCCCEEEEEEECCCCCCE
TVPFSFTFQSGELKDYYQDWAILKYNEDVGQLHKTDAQGNRIKLRFATLLAKKIS
EEEEEEEECCCCHHHHHCCCEEEEECCCHHHHHCCCCCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]