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The map label for this gene is lysN [H]

Identifier: 51596260

GI number: 51596260

Start: 2271388

End: 2272548

Strand: Direct

Name: lysN [H]

Synonym: YPTB1934

Alternate gene names: 51596260

Gene position: 2271388-2272548 (Clockwise)

Preceding gene: 51596258

Following gene: 51596263

Centisome position: 47.87

GC content: 47.29

Gene sequence:

>1161_bases
ATGAATAAAATTATAACGGATCAGCGTCACCAATTTTCCTCACGAGTGAATGACCTTCACCCGTCGCCAATTAGGGAAAT
ACTGTCTGTCATTGATCGTCCGGGAATGATCTCGTTTGCCGGCGGATTACCCGCAGTAGAAAGTTTTCCTCATATGAGCC
TTGAGGGAATGCCGCAGCCGATGCTGCAATATGGCGCGAGTGAAGGGGAGTTGGAATTACGTCAACAGATTGCTCAAAAT
TTGTGTGAGCGAGGTTTATCCTGTACTGAGGAACAAGTCCTGATTATTTCAGGCTCACAGCAGGGCATTGATCTGGTCGC
TAAGTTGTTTATTGACGAGGGAACCCCCGTCGCCGTTGAATCGCCTACCTATCTGGCTGCGTTACAGGTATTCCGTTTTT
TCGGTGCTCAATTTGTGGCTTATGATTCAACTCAGCCTGATATCGACAAGCTTCGCACCGAAAAACCTGCTTTTGCTTAT
ACTATTCCGACCTTCCAGAATCCAAGCGGTCACTGCCTTGATACTGAACAACGAGAGTTACTGGCGAAGACATGTGATGA
CATTATGTTACCGCTCTTTGAAGATGACCCGTACCATGACTTGGTTTATGACCCTTGTGAGCGTAAGCCAGTGTGTGCTT
CATTACAGCGAGCTTCGTGGATTTACCAAGGATCTTTTTCTAAAAGTTTATCCCCGGCGCTGCGTTTGGGCTATCTTGTC
GCATCTTCAGAATTGATTCCCTATTTGACACGTTTAAAACAAGCCGCAGATTTGCACAGCAGCCGGATCAGCCAATGGTT
AGTGTTACAGCAGTTGCGTAGCCCTAGGCATACTGAGCATATGCATGAACTGGCAGCCTATTATCGAACTCGCCGTGATG
CGTTTGAAATCTCCCTACAACGCCATTTTGGCTCTCTTGCGACGTGGAAAAAACCGGCTGGAGGGCTGTTCTTCTGGTTA
ACCCTTAATCGCTGCATAGATACTCGTCAACTCTTGCCTAAAGCGCTGGCAAGCAATATTGCATTTATGCCCGGAGAGTC
GTTCCTCCCTCATTCATCTGAAGGCTGCGGTCAGTTACGGCTTAATTTTAGCCATGCGACGGAAGAACAAGCGGATGTAG
GGCTGAAAATATTAGCGGGTTTAGTGCAGGAACATGCATAA

Upstream 100 bases:

>100_bases
GTTAGCAATAGGGTAGAAAGTGAAATTATGTTGACGTAATGAGCAGCGCATTTTACTTTCCATAAATGCCAAATTGGTTG
ACCTTTGTGGAAGAACTGCA

Downstream 100 bases:

>100_bases
GATGGGCTATCGGTGAATCTCATTGACTCATTAATTGAAGACGCTGAATGAATCGAAATAAATTTCAGATGGACCGAGTA
ACGAAAGCTGCCAACGCACA

Product: aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNKIITDQRHQFSSRVNDLHPSPIREILSVIDRPGMISFAGGLPAVESFPHMSLEGMPQPMLQYGASEGELELRQQIAQN
LCERGLSCTEEQVLIISGSQQGIDLVAKLFIDEGTPVAVESPTYLAALQVFRFFGAQFVAYDSTQPDIDKLRTEKPAFAY
TIPTFQNPSGHCLDTEQRELLAKTCDDIMLPLFEDDPYHDLVYDPCERKPVCASLQRASWIYQGSFSKSLSPALRLGYLV
ASSELIPYLTRLKQAADLHSSRISQWLVLQQLRSPRHTEHMHELAAYYRTRRDAFEISLQRHFGSLATWKKPAGGLFFWL
TLNRCIDTRQLLPKALASNIAFMPGESFLPHSSEGCGQLRLNFSHATEEQADVGLKILAGLVQEHA

Sequences:

>Translated_386_residues
MNKIITDQRHQFSSRVNDLHPSPIREILSVIDRPGMISFAGGLPAVESFPHMSLEGMPQPMLQYGASEGELELRQQIAQN
LCERGLSCTEEQVLIISGSQQGIDLVAKLFIDEGTPVAVESPTYLAALQVFRFFGAQFVAYDSTQPDIDKLRTEKPAFAY
TIPTFQNPSGHCLDTEQRELLAKTCDDIMLPLFEDDPYHDLVYDPCERKPVCASLQRASWIYQGSFSKSLSPALRLGYLV
ASSELIPYLTRLKQAADLHSSRISQWLVLQQLRSPRHTEHMHELAAYYRTRRDAFEISLQRHFGSLATWKKPAGGLFFWL
TLNRCIDTRQLLPKALASNIAFMPGESFLPHSSEGCGQLRLNFSHATEEQADVGLKILAGLVQEHA
>Mature_386_residues
MNKIITDQRHQFSSRVNDLHPSPIREILSVIDRPGMISFAGGLPAVESFPHMSLEGMPQPMLQYGASEGELELRQQIAQN
LCERGLSCTEEQVLIISGSQQGIDLVAKLFIDEGTPVAVESPTYLAALQVFRFFGAQFVAYDSTQPDIDKLRTEKPAFAY
TIPTFQNPSGHCLDTEQRELLAKTCDDIMLPLFEDDPYHDLVYDPCERKPVCASLQRASWIYQGSFSKSLSPALRLGYLV
ASSELIPYLTRLKQAADLHSSRISQWLVLQQLRSPRHTEHMHELAAYYRTRRDAFEISLQRHFGSLATWKKPAGGLFFWL
TLNRCIDTRQLLPKALASNIAFMPGESFLPHSSEGCGQLRLNFSHATEEQADVGLKILAGLVQEHA

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=410, Percent_Identity=28.780487804878, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI33469970, Length=410, Percent_Identity=28.780487804878, Blast_Score=155, Evalue=4e-38,
Organism=Escherichia coli, GI1787710, Length=378, Percent_Identity=25.6613756613757, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790797, Length=284, Percent_Identity=24.6478873239437, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356535, Length=359, Percent_Identity=23.6768802228412, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43364; Mature: 43364

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIITDQRHQFSSRVNDLHPSPIREILSVIDRPGMISFAGGLPAVESFPHMSLEGMPQP
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCCCCCCCH
MLQYGASEGELELRQQIAQNLCERGLSCTEEQVLIISGSQQGIDLVAKLFIDEGTPVAVE
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEC
SPTYLAALQVFRFFGAQFVAYDSTQPDIDKLRTEKPAFAYTIPTFQNPSGHCLDTEQREL
CCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHH
LAKTCDDIMLPLFEDDPYHDLVYDPCERKPVCASLQRASWIYQGSFSKSLSPALRLGYLV
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHH
ASSELIPYLTRLKQAADLHSSRISQWLVLQQLRSPRHTEHMHELAAYYRTRRDAFEISLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RHFGSLATWKKPAGGLFFWLTLNRCIDTRQLLPKALASNIAFMPGESFLPHSSEGCGQLR
HHHCHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEE
LNFSHATEEQADVGLKILAGLVQEHA
EECCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKIITDQRHQFSSRVNDLHPSPIREILSVIDRPGMISFAGGLPAVESFPHMSLEGMPQP
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCCCCCCCH
MLQYGASEGELELRQQIAQNLCERGLSCTEEQVLIISGSQQGIDLVAKLFIDEGTPVAVE
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEC
SPTYLAALQVFRFFGAQFVAYDSTQPDIDKLRTEKPAFAYTIPTFQNPSGHCLDTEQREL
CCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHH
LAKTCDDIMLPLFEDDPYHDLVYDPCERKPVCASLQRASWIYQGSFSKSLSPALRLGYLV
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHH
ASSELIPYLTRLKQAADLHSSRISQWLVLQQLRSPRHTEHMHELAAYYRTRRDAFEISLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RHFGSLATWKKPAGGLFFWLTLNRCIDTRQLLPKALASNIAFMPGESFLPHSSEGCGQLR
HHHCHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEE
LNFSHATEEQADVGLKILAGLVQEHA
EECCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA