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The map label for this gene is cat2 [H]

Identifier: 51596250

GI number: 51596250

Start: 2261789

End: 2263111

Strand: Reverse

Name: cat2 [H]

Synonym: YPTB1924

Alternate gene names: 51596250

Gene position: 2263111-2261789 (Counterclockwise)

Preceding gene: 51596251

Following gene: 51596249

Centisome position: 47.7

GC content: 50.11

Gene sequence:

>1323_bases
ATGGATATACGTGCATTGTATGACGAGAAACTCACCACGCCTGAGGAGGCCGTTTCCTCTATTGCATCCGGCAGTCACCT
CTCTATGGGGATGTTTGCGGCTGAACCACCCGCGCTGCTGAAGGCGCTGGCAGATAGGGCGACAAGGGGGGATATTGGCG
ATCTACGCGTTTACTATTTTGAAACGGCCAAAATTGCCGGTGATACTATTCTGCGCTATGAGCTAAATAATCGCATCAAG
CCCTATAGCATGTTCGTCACTGCCGTGGAGCGGGCGCTCATTCGCCGAGGCATAGAGGATGGTGGGCGTAAAGTTGTCAA
TTATGTCCCATCTAATTTTCATCAAGCACCACGTCTTCTGGCCGAAGAAATTGGTATTGATACGTTCATGCATACCGTTT
CTCCGATGGATTGTCATGGCTACTTTAGCCTCGGTGTTGGAAATGACTATTCATCCCGAATTGCACGTTCAGCCAGACGA
TTCATCGTTGAGGTGAATCGGTATATGCCGCGCGTTCAGGGGGAAGCGGCGGCGATTCACATCGCTGAAGTTGATGCCAT
TGTCGAAAATCATGTCCCTTTGATTGAGATGCCAGTACGTTCAGCAATACCCGAATATACATCTATTAGCCACATCATTG
CTGACCTCGTACCTGATGGTGCCTGCTTACAAATGGGGGTGGGCGCGCTACCAAACCTCGTTTGTGGAGTGCTAAAAGAT
CGCAATGACCTAGGGATCCATACTGAAGTGTTGAACCCCGGACTGGTCGATTTAATCCGAAGGGGGGTAGTGACGAACCA
GCGAAAAACACTGGACAGGGGCAGGTCTGTTTTCACTTTTGCCATGGGGCAACAAGAAATGTACGAATACCTTAACGATC
ACCCAGCGATTTTCAGCCGGCCGGTCGATTATGTTAACGATCCCCACATCATTGCGCAAAATGACAACGTGGTATCCATT
AATTCGACCCTGCAAATTGACCTGACGGGTGCCTGTAATTCTGAACATATGCTTGGACACCAATACAGCGCTTCGGGGGG
GCAGTTGGACTTTGTCAGGGGGGCATACGCCTCTAAAGGTGGGCGCTCCATCATCGCCACGCCTTCAACTGCGGCGAAAG
GTACTGTTTCACGTATTATTCCCCGCATTGACGGACCGGTAACCACACCCCGTATCGATACCCACTATATCGTTACCGAG
TTTGGTGCTGTTAACCTCAAAGGGCTTTCTTCAACTGAACGGGCGCTGAGAATCATTGAGCTGGCACATCCTGATTTCCG
GGATGAGCTAACGCAGGCTGCTAAAAAAATGCATCTAATCTGA

Upstream 100 bases:

>100_bases
ATAGAGGTGATGAGCTTCGAACGCACGATGCTGGTTTATCGCCGCGGTCACTCACCAGAAGAAATGGCAGGATACTGAGA
AAAACAGCGAGGGTTATATC

Downstream 100 bases:

>100_bases
GATAACCCCCCTGTCAACACTCTGCCAAACAGTATTTTTCGCTCTCCGGCATGGGGAGCGCTATACGGTGTTTCCCCCTG
ACGGTCATGCAGGCGGGTGA

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNRYMPRVQGEAAAIHIAEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI

Sequences:

>Translated_440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNRYMPRVQGEAAAIHIAEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI
>Mature_440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNRYMPRVQGEAAAIHIAEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=288, Percent_Identity=28.125, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563853, Length=434, Percent_Identity=34.7926267281106, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17538151, Length=437, Percent_Identity=33.8672768878719, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI21358615, Length=431, Percent_Identity=34.338747099768, Blast_Score=224, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48396; Mature: 48396

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYF
CCCHHHHHCCCCCHHHHHHHHHCCCCCEECEECCCCHHHHHHHHHHCCCCCCCCEEEEEE
ETAKIAGDTILRYELNNRIKPYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLL
EEEHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHH
AEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARRFIVEVNRYMPRVQGEAAAIH
HHHHCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
IAEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
HHHHHHHHHCCCCEEEECHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCC
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSR
CCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHCCCEEEEEECCHHHHHHHHCCCCCHHCC
PVDYVNDPHIIAQNDNVVSINSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKG
CCCCCCCCEEEECCCCEEEECCEEEEEEECCCCCCCCCCCEECCCCCCEEEHHCHHHCCC
GRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTEFGAVNLKGLSSTERALRIIE
CCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHH
LAHPDFRDELTQAAKKMHLI
HCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYF
CCCHHHHHCCCCCHHHHHHHHHCCCCCEECEECCCCHHHHHHHHHHCCCCCCCCEEEEEE
ETAKIAGDTILRYELNNRIKPYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLL
EEEHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHH
AEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARRFIVEVNRYMPRVQGEAAAIH
HHHHCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
IAEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
HHHHHHHHHCCCCEEEECHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCC
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSR
CCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHCCCEEEEEECCHHHHHHHHCCCCCHHCC
PVDYVNDPHIIAQNDNVVSINSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKG
CCCCCCCCEEEECCCCEEEECCEEEEEEECCCCCCCCCCCEECCCCCCEEEHHCHHHCCC
GRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTEFGAVNLKGLSSTERALRIIE
CCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHH
LAHPDFRDELTQAAKKMHLI
HCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]