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The map label for this gene is flhA

Identifier: 51596002

GI number: 51596002

Start: 2017622

End: 2019700

Strand: Direct

Name: flhA

Synonym: YPTB1666

Alternate gene names: 51596002

Gene position: 2017622-2019700 (Clockwise)

Preceding gene: 51596001

Following gene: 51596003

Centisome position: 42.52

GC content: 51.9

Gene sequence:

>2079_bases
ATGGCTAATTTGGCCGCCCTGCTACGTTTACCGGGCAATTTTAAAGACACACAGTGGCAAATTCTCGCTGGGCCAATCCT
GATCTTAATGATCTTGTCGATGATGATTTTGCCTCTGCCTCCATTCGCCTTGGATTTGTTGTTTACCTTTAATATTGCAC
TTTCCATCATGGTGTTACTGGTGGCCATGTTCACCCAGCGCACACTGGATTTTGCCGCCTTTCCGACCATCCTGTTGTTC
TCTACTTTATTGCGTCTATCACTAAACGTGGCTTCCACGCGTATTATTCTGATGGATGGCCACACCGGGGGCGCGGCGGC
CGGGCGAGTGGTTGAGGCATTTGGTCACTTCCTGGTTGGTGGTAATTTTGCCATTGGTATTGTGGTCTTTGTCATTTTGG
TGGTGATCAACTTTATGGTGATCACCAAAGGGGCTGGGCGTATTGCTGAAGTGGGTGCCCGTTTCGTTTTGGATGGTATG
CCCGGTAAACAGATGGCAATCGACGCTGATTTAAATGCCGGATTGAGCGGCGAAGATGAAGCGAAAAAACGCCGCTCTGA
CGTTACGCAAGAGGCTGACTTCTACGGTTCGATGGACGGGGCCAGTAAATTTGTTCGCGGTGATGCGGTTGCTGGTTTGC
TGATCATGGTGATTAACGTGGTGGGGGGGCTACTGGTCGGCGTGCTTCAGCACAACATGGCTTTTGGTCATGCAGCAGAA
ACCTATACCTTGCTCACCATTGGCGATGGTTTGGTTGCTCAAATCCCTGCGCTGGTAATTTCGACCGCCGCAGGGGTGAT
TGTCACTCGCGTCAGTACTGATCAAGACGTTGGCCAGCAAATGGTCACCCAACTGTTCAACAACCCACGGGTGATGGTAT
TAAGTGCCAGCGTACTGGGTCTGCTGGGAATGGTGCCTGGGATGCCGAATTTTGTCTTCCTACTATTTACCGCAGCATTA
TTAGCCTTGGCTTGGCGCTTACGTGGTAAACAAACACAGCAGCCTGTGGCAGTAGAAGCACCCGTGGTGCAAGATCAGCA
ACAGGGCGCAGAGGCGACATGGGCAGATGTTCAACTGGAAGATCCGCTGGGGATGGAAGTGGGTTACCGCTTGATACCGA
TGGTGGATTTCCAGCAAAACGGTGAATTATTGGGCCGAATTCGTAGTATCCGCAAAAAATTTGCGCAAGAGATGGGCTAC
CTACCGCCAGTCGTGCATATTCGCGATAACCTGGAATTACCCCCCGCTAATTATCGGATATTAATGAAAGGGGTTGAAAT
TGGCAGTGGTGAGGCACACCCAGGGCGCTGGCTGGCGATTAACCCCGGTAACGCCGTTGGTACATTACCGGGTGAAGCCA
CCCACGACCCGGCCTTCGGTCTGGCGGCGGTGTGGATAGAGAGTGCGTTACGTGAGCAGGCACAAATTCAGGGCTTTACC
GTCGTTGAGGCCAGTACGGTGGTGGCGACGCATTTGAACCATGTGCTCAGCCAATATGCCAACGAGTTGTTCGGCCGTCA
GGAAACTCAACAGCTCCTTGATCGTGTGACGCAAGAGATGCCAAAGTTGACCGAAGACTTTATCCCTGGGGTGGTGACAT
TAACCACGTTACATAAAGTTTTGCAAAATCTGTTAATGGAGCGGGTCTCGATCCGCGACATGCGCACCATTATTGAAACA
CTGGCCGAACATGCGCCAAACCAGGCTGATCCTTACGAATTAACCGCGACAGTGCGAGTGGCATTAGGGCGTTCAATTGC
GCAGCAGTGGTTCCCTGGGAATGGTGAAATTCAGGTTATCGGGTTGGATGCTGCCTTGGAGCGCTTATTATTACAAGCTC
TGCAAGGGGGGAGTGGCTTGGAGCCGGGTCTGGCTGATCGTCTGCTGGATCAATCCAAACAAGCGTTGCAACGCCAAGAG
ATGCTAGGCGCACCGCCTGTATTATTGGTTAATCATGCACTACGGGCATTATTGGCCCGCTTCTTGCGCCGTAGCTTGCC
GCAAATGGTGGTGCTGTCTAACCTGGAAATTGGTGATAACCGCCAGATTCGTATGACCTCGACGATAGGATCCGCCTAA

Upstream 100 bases:

>100_bases
AGCGGGAAGGCGGGCTTATCCCGAAAAAACCTGAACATCTGCCGGTGCCGGAAGCACTGGATTTTGCAACAGAGAGTGAG
ACAAAGAGTGAGACAGACTA

Downstream 100 bases:

>100_bases
TGTTGATTCGGGCCTCCCACCGTGTATTGATTCTATTAGCGGCCAGCCTGTTGCCGCTTAAGATTAACGCCGCATCCGGT
TCTTGGGTAGCGGATAATAT

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLF
STLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVGGNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLSGEDEAKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAE
TYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLGLLGMVPGMPNFVFLLFTAAL
LALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGY
LPPVVHIRDNLELPPANYRILMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFT
VVEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKVLQNLLMERVSIRDMRTIIET
LAEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVIGLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQE
MLGAPPVLLVNHALRALLARFLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA

Sequences:

>Translated_692_residues
MANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLF
STLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVGGNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLSGEDEAKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAE
TYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLGLLGMVPGMPNFVFLLFTAAL
LALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGY
LPPVVHIRDNLELPPANYRILMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFT
VVEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKVLQNLLMERVSIRDMRTIIET
LAEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVIGLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQE
MLGAPPVLLVNHALRALLARFLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA
>Mature_691_residues
ANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLFS
TLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVGGNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGMP
GKQMAIDADLNAGLSGEDEAKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAET
YTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLGLLGMVPGMPNFVFLLFTAALL
ALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGYL
PPVVHIRDNLELPPANYRILMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFTV
VEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKVLQNLLMERVSIRDMRTIIETL
AEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVIGLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQEM
LGAPPVLLVNHALRALLARFLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=690, Percent_Identity=83.9130434782609, Blast_Score=1150, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74924; Mature: 74793

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLL
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLDFAAFPTILLFSTLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
GNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLSGEDE
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAE
HHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLG
EEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEHHHHHH
LLGMVPGMPNFVFLLFTAALLALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHCCCCCCEECEEEC
DPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGYLPPVVHIRDNLELPPANYRI
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEE
LMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFT
EEEECEECCCCCCCCCEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLMERVSIRDMRTIIETLAEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQEMLGAPPVLLVNHALRALLAR
EHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA
HHHHCCCCEEHHCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure 
ANLAALLRLPGNFKDTQWQILAGPILILMILSMMILPLPPFALDLLFTFNIALSIMVLL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLDFAAFPTILLFSTLLRLSLNVASTRIILMDGHTGGAAAGRVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
GNFAIGIVVFVILVVINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLSGEDE
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAFGHAAE
HHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSASVLG
EEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEHHHHHH
LLGMVPGMPNFVFLLFTAALLALAWRLRGKQTQQPVAVEAPVVQDQQQGAEATWADVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHCCCCCCEECEEEC
DPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGYLPPVVHIRDNLELPPANYRI
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEE
LMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATHDPAFGLAAVWIESALREQAQIQGFT
EEEECEECCCCCCCCCEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHVLSQYANELFGRQETQQLLDRVTQEMPKLTEDFIPGVVTLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLMERVSIRDMRTIIETLAEHAPNQADPYELTATVRVALGRSIAQQWFPGNGEIQVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GLDAALERLLLQALQGGSGLEPGLADRLLDQSKQALQRQEMLGAPPVLLVNHALRALLAR
EHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLRRSLPQMVVLSNLEIGDNRQIRMTSTIGSA
HHHHCCCCEEHHCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387224 [H]