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The map label for this gene is fecC [C]

Identifier: 51595710

GI number: 51595710

Start: 1632613

End: 1633671

Strand: Direct

Name: fecC [C]

Synonym: YPTB1370

Alternate gene names: 51595710

Gene position: 1632613-1633671 (Clockwise)

Preceding gene: 51595709

Following gene: 51595711

Centisome position: 34.41

GC content: 51.84

Gene sequence:

>1059_bases
ATGGCAACCTTTTTAGAGCCCCTCACGCAGGGACGGCAATTTTTTCAGCAACTTCATCTACGACGCGGGTTATTCACACT
GGCATTGATTGGCTCGCTACTGGCCGCTATGGTCATCGATCTGGCCACTGGTGCGGCCAACCTTAGCCCACTTGATGTAT
TGCGGCTGTTTCTGGTGGATTCTTCGCAGCATGATGAACTACACCAGATCATTTTTTGGTCCATTCGTTTGCCGATGACG
TTAACCGCCGTGGTGGTGGGCGCGAGTTTGGGTTTGGCTGGCTTGTTGATGCAAACCGTACTGGCGAATCCGTTAGCCAG
TCCTTATACCTTGGGGATTTCAGCCGCGGCAGGATTTGGTGCCGCATTATCGATCATCACTGGCTTCAGCGTGGGGGGAG
TCTTGTCATTAGGCACCCCATTATTGGCTTCACTGATGGCATTACTGGCCTGCCTGCCCATTTACTTTATGGGCCAACGG
CAGGGGATGACACCGCAAATTCTGGTGTTGAGCGGCATTGTGGTGCTGTTCTTCTTCCAGTCGTTGCAATCACTCATGTT
ATTTCTGGCCTCACCAGAAGCGATGCAACAAATTGTATTCTGGCTGTTTGGCAGCCTGCTAAAAGCCAATATGCAGGGGG
TGCTAATGACGGGCAGCGTACTGGCTTGTTCACTGGTTATCTGTTTGCAGCAGGCATGGCGATTGACCGCGCTTTCAGCG
GGGGAGGAGCAAGCGCTAGGTTTGGGGATTAACGTAAGCGCCTTACGTAAGTTAGCGTTTCTTCTGGCGACCTTGTTGAC
CGCCGCCTCTGTGTCTTTTGTCGGCACTATCGGCTTTATCGGTTTGGTCGCCCCTCACTTCGCCCGTATGTTGGTCGGCG
AAGATCAACGCTATCTGATCGGTATTTCGGCACTTTGTGGCAGCCTGCTATTGGTTCTGGCCTCTATCATTTCCAAACTC
ATACTGCCAAATGGTGTCGTGCCGATCGGCATTATTATTGCGCTGATCGGTGTCCCGGTATTGTTCTATTTTGTGACTAA
ACAGGTGAAACGGGCATGA

Upstream 100 bases:

>100_bases
TTGAAGATGTGAACCCGCAACGTAATCTCGAAACGTTTTATGAAGAGTATCTGCCCATCAAAGCCGATGGCGTATTTATG
CAGCAATGGCAGGGAGAATA

Downstream 100 bases:

>100_bases
CGCAACTGACGTTAAAGCACGTCGGCGTCACGCTTCATAAACGCCCACTGCTCACCGATATTTCTCTAACGTGGCCTGCG
GCACAGGTGAGCGGCATTAT

Product: FecCD ABC type transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MATFLEPLTQGRQFFQQLHLRRGLFTLALIGSLLAAMVIDLATGAANLSPLDVLRLFLVDSSQHDELHQIIFWSIRLPMT
LTAVVVGASLGLAGLLMQTVLANPLASPYTLGISAAAGFGAALSIITGFSVGGVLSLGTPLLASLMALLACLPIYFMGQR
QGMTPQILVLSGIVVLFFFQSLQSLMLFLASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQAWRLTALSA
GEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLVLASIISKL
ILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA

Sequences:

>Translated_352_residues
MATFLEPLTQGRQFFQQLHLRRGLFTLALIGSLLAAMVIDLATGAANLSPLDVLRLFLVDSSQHDELHQIIFWSIRLPMT
LTAVVVGASLGLAGLLMQTVLANPLASPYTLGISAAAGFGAALSIITGFSVGGVLSLGTPLLASLMALLACLPIYFMGQR
QGMTPQILVLSGIVVLFFFQSLQSLMLFLASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQAWRLTALSA
GEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLVLASIISKL
ILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA
>Mature_351_residues
ATFLEPLTQGRQFFQQLHLRRGLFTLALIGSLLAAMVIDLATGAANLSPLDVLRLFLVDSSQHDELHQIIFWSIRLPMTL
TAVVVGASLGLAGLLMQTVLANPLASPYTLGISAAAGFGAALSIITGFSVGGVLSLGTPLLASLMALLACLPIYFMGQRQ
GMTPQILVLSGIVVLFFFQSLQSLMLFLASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQAWRLTALSAG
EEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLVLASIISKLI
LPNGVVPIGIIIALIGVPVLFYFVTKQVKRA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=281, Percent_Identity=34.5195729537367, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790740, Length=299, Percent_Identity=32.4414715719064, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786805, Length=285, Percent_Identity=35.4385964912281, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=34.7222222222222, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788004, Length=279, Percent_Identity=30.4659498207885, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786804, Length=333, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37268; Mature: 37136

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFLEPLTQGRQFFQQLHLRRGLFTLALIGSLLAAMVIDLATGAANLSPLDVLRLFLVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
SSQHDELHQIIFWSIRLPMTLTAVVVGASLGLAGLLMQTVLANPLASPYTLGISAAAGFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHH
AALSIITGFSVGGVLSLGTPLLASLMALLACLPIYFMGQRQGMTPQILVLSGIVVLFFFQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
SLQSLMLFLASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQAWRLTALSA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCC
GEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLI
CCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GISALCGSLLLVLASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATFLEPLTQGRQFFQQLHLRRGLFTLALIGSLLAAMVIDLATGAANLSPLDVLRLFLVD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
SSQHDELHQIIFWSIRLPMTLTAVVVGASLGLAGLLMQTVLANPLASPYTLGISAAAGFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHH
AALSIITGFSVGGVLSLGTPLLASLMALLACLPIYFMGQRQGMTPQILVLSGIVVLFFFQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
SLQSLMLFLASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQAWRLTALSA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCC
GEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLI
CCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GISALCGSLLLVLASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]