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The map label for this gene is xylB [H]

Identifier: 51595664

GI number: 51595664

Start: 1576076

End: 1577629

Strand: Direct

Name: xylB [H]

Synonym: YPTB1323

Alternate gene names: 51595664

Gene position: 1576076-1577629 (Clockwise)

Preceding gene: 51595663

Following gene: 51595665

Centisome position: 33.22

GC content: 58.49

Gene sequence:

>1554_bases
ATGCAGGCGCTTTTGGGCATTGATATCGGCACCTCGGGGTGTAAGGCGTTGCTGATCGGTATCGATGGTGCGGTGATCGC
CGCCGATACCGCGAGTTATCCATTATCTCAACCCCAACTCGGTTGGGCTGAACAAGATCCTGAGCTGTGGGTCGAGGGGG
CGCGTCGAGCCGTGGCAGGAGCATTGGCTAAAGCGCCAACGCTGGAGTTGCTCTGCGTGGGGCTATCCGGGCAAATGCAT
GGGCTGGTATCACTTGATGCTGGGCATCAGGTGTTGCGCCCGGCGATCCTCTGGAACGACCAACGCAATAGTGCTGAATG
CGAGCAGATTACCGAGGCAGCGGGGGGGCTAAAAGGATTGTTGGCGGCGACTAACAACCGAATGTTGGTGGGCTACACCG
GTGGCAAGATTGTGTGGATGCAGCAGCATGAGCCTGATCTCTTCGCTCGCATGACCACGGTACTGAACCCCAAAGACTAC
TTGCGGCTGCGTTTGACGGGGGAGGTCGCCACTGAAGTTTCGGATGCCTCGGGGACCGGGCTTTTCGATGTACGTGCACG
CCAGTGGGCGAGTGATCTTATTGAGAACGTGGGGATTGACCGCGCTTTACTGCCCCCCGTATTTGAATCGCAGGTGATCT
CTGGCCAGGTCTCAGCGGTGGGGGCCGAGCTATTCGGTATTCCCAAAGGCACGCCCGTTGCTGGTGGTGGCGGTGATGCT
GTGATACAGACCTTCGGTTCTGGGGTGATCGCTCCGGGTGAGTTACAAACCACCATCGGCACGGCGGGCATCCTTGCAGC
GGTATTGGATACACCACAGGCGAACCCCGACGGGCGGTTACAGGTTTTTTGTCATGTTGTGGCTGATAAATGGCACTGCA
TGGGGGTCTCGCTGAACGCTGGCGGCGCGATGAGTTGGTTTCGTGACACGTTTTATGTGGGTGTTAATGCGGCGGTTCCT
TCTTTTGATCAGTTCACGCCTTCTGATCAAATCACACCTTCTTTTGAGCAGATCGTTGCTGAGGCGGCAGCCAGCCCGGC
AGGGGCGCGCGGTCTGCTGTTCTTACCTTATCTGAATGGTGAACGTTGCCCTCATCCTGATCCTGCGGCGCGCGGTGCCT
TCATTGGTCTGACAGCCTGCCATCATCGTGGCGATGTGGCACGTGCAGTCATGGAGGGGGTGGTCCACGCCCTTGTGGAT
ATGCACACCTTGATGAAGCCATTGGGCATCAATGGGCGGGTTGTAAAAACATCCGGTGGCGGTGCACGTTCGCCCCTTTG
GCGGCAGATGCAGGCAGATATTTTCGGCTGTGATGTCCTTACCACAAAAGGGGCTGCTGAAGGCGCCGCATTCGGTGCCG
CGCTGGTGGCGGGATTGGCTATCGGGGTTTGGCCCGATGCGACGAGCGCGACGGCGAACTGCCGTATCATCACGCGCGAC
CCCCCCAATCCCGCAACCGCGGCGGTTGTTGCTGAGGCCCAACGCATTTACCGTACTCTTTACCCGGCGCTGAGAGAAAC
CTTCGCAGAACTTGGCGACCCCACCTTTATGTAG

Upstream 100 bases:

>100_bases
TAAGCAAAGTGGCGTGGGCTACGAGCATGGCCGTGAGGGGTTGCTGGAGTATTTCAATTTCAAGCACATCCGCTTGTACC
ACGGTATCGGGGACTAAACC

Downstream 100 bases:

>100_bases
TCATGATCAGGAGTCACGCATGAGCAATCAACAAAATGACGCCAAGAGGGCTGCCGCCCGTCGGGTGATTCAGGATTTCG
TGTTCGATGGCATGACGTTG

Product: carbohydrate kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAVLDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHHRGDVARAVMEGVVHALVD
MHTLMKPLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRD
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM

Sequences:

>Translated_517_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAVLDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHHRGDVARAVMEGVVHALVD
MHTLMKPLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRD
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM
>Mature_517_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAVLDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHHRGDVARAVMEGVVHALVD
MHTLMKPLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRD
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=499, Percent_Identity=24.0480961923848, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41393575, Length=436, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI42794763, Length=455, Percent_Identity=24.3956043956044, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI189409120, Length=455, Percent_Identity=24.6153846153846, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4504007, Length=455, Percent_Identity=24.6153846153846, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI18860918, Length=259, Percent_Identity=23.5521235521236, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1789987, Length=507, Percent_Identity=36.4891518737673, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI1790005, Length=526, Percent_Identity=27.9467680608365, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1787789, Length=372, Percent_Identity=26.0752688172043, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790361, Length=484, Percent_Identity=25.6198347107438, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789168, Length=433, Percent_Identity=23.094688221709, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=464, Percent_Identity=24.7844827586207, Blast_Score=101, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6321633, Length=345, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864214, Length=484, Percent_Identity=24.3801652892562, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24655555, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655560, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655570, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655574, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655565, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24654573, Length=415, Percent_Identity=24.0963855421687, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356607, Length=557, Percent_Identity=21.903052064632, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54104; Mature: 54104

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAG
CCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALAKAPTLELLCVGLSGQMHGLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGL
HHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHEEECCCCCCHHHHHHHHHHCCHHEE
LAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDYLRLRLTGEVATEVSDASGTG
EEECCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCC
LFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
EEEHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHH
VIQTFGSGVIAPGELQTTIGTAGILAAVLDTPQANPDGRLQVFCHVVADKWHCMGVSLNA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEEEECC
GGAMSWFRDTFYVGVNAAVPSFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNG
CCCHHHHHCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCC
ERCPHPDPAARGAFIGLTACHHRGDVARAVMEGVVHALVDMHTLMKPLGINGRVVKTSGG
CCCCCCCHHHCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRD
CCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECC
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAG
CCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALAKAPTLELLCVGLSGQMHGLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGL
HHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHEEECCCCCCHHHHHHHHHHCCHHEE
LAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDYLRLRLTGEVATEVSDASGTG
EEECCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCC
LFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
EEEHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHH
VIQTFGSGVIAPGELQTTIGTAGILAAVLDTPQANPDGRLQVFCHVVADKWHCMGVSLNA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEEEECC
GGAMSWFRDTFYVGVNAAVPSFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNG
CCCHHHHHCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCC
ERCPHPDPAARGAFIGLTACHHRGDVARAVMEGVVHALVDMHTLMKPLGINGRVVKTSGG
CCCCCCCHHHCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRD
CCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECC
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]